Results 11 to 20 of about 91,412 (386)
Posttranslational regulation of the GCN5 and PCAF acetyltransferases
PLoS Genetics, 2022 General control nonderepressible 5 protein (Gcn5) and its homologs, including p300/CBP-associated factor (PCAF), are lysine acetyltransferases that modify both histone and non-histone proteins using acetyl coenzyme A as a donor substrate.
Onyekachi E. Ononye, Michael Downey
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Lysine Acetyltransferases and Their Role in AR Signaling and Prostate Cancer
Frontiers in Endocrinology, 2022 The development and growth of a normal prostate gland, as well as its physiological functions, are regulated by the actions of androgens through androgen receptor (AR) signaling which drives multiple cellular processes including transcription, cellular ...
Bharti Jaiswal +2 more
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Classification and phylogeny for the annotation of novel eukaryotic GNAT acetyltransferases.
PLoS Computational Biology, 2020 The enzymes of the GCN5-related N-acetyltransferase (GNAT) superfamily count more than 870 000 members through all kingdoms of life and share the same structural fold.
Bojan Krtenic +3 more
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Frontiers in Microbiology, 2019 Aminoglycoside acetyltransferases are important determinants of resistance to aminoglycoside antibiotics in most bacterial genera. In mycobacteria, however, aminoglycoside acetyltransferases contribute only partially to aminoglycoside susceptibility ...
Fernando Sanz-García +12 more
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Identification of Novel Protein Lysine Acetyltransferases in
mBio, 2018 Posttranslational modifications, such as Nε-lysine acetylation, regulate protein function. Nε-lysine acetylation can occur either nonenzymatically or enzymatically.
David G. Christensen +8 more
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Theranostics, 2022 The histone acetyltransferases CBP and p300, often referred to as CBP/p300 due to their sequence homology and functional overlap and co-operation, are emerging as critical drivers of oncogenesis in the past several years.
Qingjuan Chen +5 more
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Roles of histone acetylation sites in cardiac hypertrophy and heart failure
Frontiers in Cardiovascular Medicine, 2023 Heart failure results from various physiological and pathological stimuli that lead to cardiac hypertrophy. This pathological process is common in several cardiovascular diseases and ultimately leads to heart failure.
Masafumi Funamoto +3 more
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Fluorescence umpolung enables light-up sensing of N-acetyltransferases and nerve agents
Nature Communications, 2021 Intramolecular charge transfer (ICT) is a fundamental mechanism that enables the development of numerous fluorophores and probes for bioimaging and sensing.
Chenxu Yan +7 more
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Plant Cell Wall Polysaccharide O-Acetyltransferases. [PDF]
Plants (Basel)Plant cell walls are largely composed of polysaccharide polymers, including cellulose, hemicelluloses (xyloglucan, xylan, mannan, and mixed-linkage β-1,3/1,4-glucan), and pectins.
Zhong R +5 more
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Histone Acetyltransferases and Stem Cell Identity
Cancers, 2021 Simple Summary Gene regulation is the major mechanism that allows us to develop from a single cell to a fully formed adult body containing numerous organs and tissues, >200 cell types and a total of about 50 trillion cells. One of the ways our cells turn
Ruicen He, Arthur Dantas, K. Riabowol
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