Results 11 to 20 of about 93,058 (385)
Classification and phylogeny for the annotation of novel eukaryotic GNAT acetyltransferases.
PLoS Computational Biology, 2020 The enzymes of the GCN5-related N-acetyltransferase (GNAT) superfamily count more than 870 000 members through all kingdoms of life and share the same structural fold.
Bojan Krtenic +3 more
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Frontiers in Microbiology, 2019 Aminoglycoside acetyltransferases are important determinants of resistance to aminoglycoside antibiotics in most bacterial genera. In mycobacteria, however, aminoglycoside acetyltransferases contribute only partially to aminoglycoside susceptibility ...
Fernando Sanz-García +12 more
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Identification of Novel Protein Lysine Acetyltransferases in
mBio, 2018 Posttranslational modifications, such as Nε-lysine acetylation, regulate protein function. Nε-lysine acetylation can occur either nonenzymatically or enzymatically.
David G. Christensen +8 more
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Theranostics, 2022 The histone acetyltransferases CBP and p300, often referred to as CBP/p300 due to their sequence homology and functional overlap and co-operation, are emerging as critical drivers of oncogenesis in the past several years.
Qingjuan Chen +5 more
semanticscholar +1 more source
Fluorescence umpolung enables light-up sensing of N-acetyltransferases and nerve agents
Nature Communications, 2021 Intramolecular charge transfer (ICT) is a fundamental mechanism that enables the development of numerous fluorophores and probes for bioimaging and sensing.
Chenxu Yan +7 more
semanticscholar +1 more source
Histone Acetyltransferases and Stem Cell Identity
Cancers, 2021 Simple Summary Gene regulation is the major mechanism that allows us to develop from a single cell to a fully formed adult body containing numerous organs and tissues, >200 cell types and a total of about 50 trillion cells. One of the ways our cells turn
Ruicen He, Arthur Dantas, K. Riabowol
semanticscholar +1 more source
Nature Communications, 2023 Acinetobacter baumannii is a nosocomial pathogen highly resistant to environmental changes and antimicrobial treatments. Regulation of cellular motility and biofilm formation is important for its virulence, although it is poorly described at the ...
Julija Armalytė +8 more
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A synopsis of eukaryotic Nα-terminal acetyltransferases: nomenclature, subunits and substrates [PDF]
BMC Proceedings, 2009 We have introduced a consistent nomenclature for the various subunits of the NatA-NatE N-terminal acetyltransferases from yeast, humans and other eukaryotes.
Polevoda Bogdan +2 more
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Communications Biology, 2022 A comprehensive functional and structural study of the Antibiotic_NAT family of aminoglycoside acetyltransferases provides new insight into the molecular mechanisms underlying resistance to existing and emerging aminoglycoside antibiotics.
Peter J. Stogios +11 more
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Structural insights into WcbI, a novel polysaccharide-biosynthesis enzyme
IUCrJ, 2014 Capsular polysaccharides (CPSs) are protective structures on the surfaces of many Gram-negative bacteria. The principal CPS of the human pathogen and Tier 1 select agent Burkholderia pseudomallei consists of a linear repeat of –3)-2-O-acetyl-6-deoxy-β-d ...
Mirella Vivoli +4 more
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