Results 71 to 80 of about 3,011 (167)

Characterization and Design Framework for Micro‐ and Nanoscale Printed Metal Interconnects in Hybrid Electronic Systems

Advanced Materials Technologies, Volume 11, Issue 11, 5 June 2026.
This work establishes a framework for high‐resolution printed interconnects by coupling e‐jet printing control, multilayer deposition, and sintering optimization. Ink properties and printing speed influence particle stacking, while different sintering atmospheres drive distinct microstructural evolution.
Kaifan Yue, Siddharth Kurup, Rebecca Banner, Calib Lanier, Eric Vogel, Michael Filler, Kira Barton   +6 more
wiley   +1 more source

Channel Dysfunction as the Basis for Comorbidities in Multiple Sclerosis and Depression

Archiv der Pharmazie, Volume 359, Issue 6, June 2026.
Ion channel remodelling induced by neuroinflammation in multiple sclerosis alters neuronal excitability and immune signalling, creating shared molecular pathways that link multiple sclerosis pathology to depression and reveal novel pharmacological targets.
Nicole Rychlik, Kay Jüngling, Sven G. Meuth, Thomas Budde, Marta Méndez‐Couz   +4 more
wiley   +1 more source

Unraveling Inflammatory Pain: A Narrative Review of Molecular Pathways and Multidisciplinary Treatments

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background Inflammatory pain is a widespread global health concern arising from complex molecular pathways triggered by a consequence of tissue damage and immune activation. It significantly impacts quality of life and functional outcomes, necessitating a comprehensive understanding of underlying mechanisms and multidisciplinary approaches for
Fatma Mohamed Elmansy, Mohamed Goda Elbqry, Saddam Ahmed Al‐Ahdal, Fatima S. O. Ashmieg, Patience Osose Nasir, Nasiru Mohammed Abdullahi, Mohammed Nader Shalaby   +6 more
wiley   +1 more source

Characterization of cutaneous and articular sensory neurons

Molecular Pain, 2016
Background A wide range of stimuli can activate sensory neurons and neurons innervating specific tissues often have distinct properties. Here, we used retrograde tracing to identify sensory neurons innervating the hind paw skin (cutaneous) and ankle/knee
Ines da Silva Serra MPharm, Zoé Husson MSc, PhD, Jonathan D. Bartlett, Ewan St. John Smith MPharmacol, PhD   +3 more
doaj   +1 more source

Experimental High‐Throughput Electrochemistry

ChemElectroChem, Volume 13, Issue 9, 5 May 2026.
This review highlights experimental high‐throughput electrochemistry as a powerful approach to accelerate electrochemical research. Key technologies such as automated platforms, microelectrode arrays, and machine learning‐based optimization are discussed, with a focus on applications in electrocatalysis, battery research, and electrosynthesis ...
Jens Noack
wiley   +1 more source

Bilirubin as a Modulator of WNK1 Protein Signaling: Implications for Neuroinflammatory Diseases

Advanced Science, Volume 13, Issue 27, 13 May 2026.
ABSTRACT Previously regarded merely as a potentially harmful waste product of heme catabolism, bilirubin has now emerged as a pleiotropic molecule with potent antioxidant, anti‐inflammatory, and hormone‐like properties. Recent findings have revealed protective effects against cardiovascular, metabolic, autoimmune, and neoplastic diseases, as well as ...
Sri Jayanti, Libor Vítek, Silvia Gazzin, Claudio Tiribelli   +3 more
wiley   +1 more source

APETx-Like Peptides from the Sea Anemone Heteractis crispa, Diverse in Their Effect on ASIC1a and ASIC3 Ion Channels

Toxins, 2020
Currently, five peptide modulators of acid-sensing ion channels (ASICs) attributed to structural class 1b of sea anemone toxins have been described. The APETx2 toxin is the first and most potent ASIC3 inhibitor, so its homologs from sea anemones are ...
Rimma S. Kalina, Sergey G. Koshelev, Elena A. Zelepuga, Natalia Y. Kim, Sergey A. Kozlov, Emma P. Kozlovskaya, Margarita M. Monastyrnaya, Irina N. Gladkikh   +7 more
doaj   +1 more source

Involvement of Acid-Sensing Ion Channel 1b in the Development of Acid-Induced Chronic Muscle Pain

Frontiers in Neuroscience, 2019
Acid-sensing ion channels (ASICs) are important acid sensors involved in neural modulation in the central nervous system and pain-associated tissue acidosis in the peripheral system.
Chu-Ting Chang, Sitt Wai Fong, Sitt Wai Fong, Cheng-Han Lee, Yu-Chia Chuang, Shing-Hong Lin, Shing-Hong Lin, Chih-Cheng Chen, Chih-Cheng Chen   +8 more
doaj   +1 more source

Molecular determinants of ASIC1 modulation by divalent cations

Scientific Reports
Acid-sensing ion channels (ASICs) are proton-gated cation channels widely expressed in the nervous system. ASIC gating is modulated by divalent cations as well as small molecules; however, the molecular determinants of gating modulation by divalent ...
Yi Liu, Jichun Ma, Renee L. DesJarlais, Rebecca Hagan, Jason Rech, Changlu Liu, Robyn Miller, Jeffrey Schoellerman, Jinquan Luo, Michael Letavic, Bruce Grasberger, Michael P. Maher   +11 more
doaj   +1 more source

Acid-sensing (proton-gated) ion channels (ASICs) in GtoPdb v.2025.3

IUPHAR/BPS Guide to Pharmacology CITE
Acid-sensing ion channels (ASICs, nomenclature as agreed by NC-IUPHAR [52, 2, 3]) are members of a Na+ channel superfamily that includes the epithelial Na+ channel (ENaC), the FMRF-amide activated channel (FaNaC) of invertebrates, the degenerins (DEG) of Caenorhabitis elegans, channels in Drosophila melanogaster and the mammalian bile acid-activated ...
Stephan Kellenberger, Lachlan D. Rash
openaire   +3 more sources