Results 41 to 50 of about 484,701 (303)

The domestication of the probiotic bacterium Lactobacillus acidophilus [PDF]

, 2014
Lactobacillus acidophilus is a Gram-positive lactic acid bacterium that has had widespread historical use in the dairy industry and more recently as a probiotic. Although L.
Aerts, Maarten, Bray, James E, Bull, Matthew J, Jolley, Keith A, Mahenthiralingam, Eshwar, Maiden, Martin CJ, Marchesi, Julian R, Vandamme, Peter   +7 more
core   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

THE PRODUCTION OF LACTIC ACID BY THE LOCAL IRAQI STRAIN ENTEROCOCCUS FAECIUM [PDF]

Basrah Journal of Veterinary Research, 2014
Lactic acid is an important carboxylic acid used in different aspects of life. In this study a pure isolate of homofermentative lactic acid bacteria Enterococcus faecium was isolated , and characterized by morphological examinations with
Amal Kadhim Al Asady, Wissal Audah Hassan Alhilfi, Maytham A. Alhamdani   +2 more
doaj   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Advanced Fermentation Techniques for Lactic Acid Production from Agricultural Waste

Fermentation, 2023
Lactic acid plays an important role in industrial applications ranging from the food industry to life sciences. The growing demand for lactic acid creates an urgent need to find economical and sustainable substrates for lactic acid production ...
Jiaqi Huang, Jianfei Wang, Shijie Liu
doaj   +1 more source

The preparation of crystalline lactic acid [PDF]

, 1933
On account of its importance in intermediary metabolism, lactic acid was among the first compounds chosen in our plan, which we have described in a previous communication (1), to augment the available data on the free energies of formation of substances ...
Borsook, Henry, Huffman, Hugh M., Liu, Yun-Pu   +2 more
core  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Hyperammonemia reduces the populations of beneficial lactobacilli and bifidobacteria, disrupting the metabolic balance of the gut microbiome in rats

Frontiers in Microbiology
IntroductionThe gut microbiome (GM) plays a critical role in metabolic and neurological health and is implicated in hepatic encephalopathy (HE). Chronic hyperammonemia (HA), a major contributor to cognitive and motor impairment in HE, may influence GM ...
Lola Giner-Pérez, Vicente Felipo, Paula Izquierdo-Altarejos, Paula Izquierdo-Altarejos, Marta Llansola, Gaspar Pérez Martínez   +5 more
doaj   +1 more source

Transcriptional analysis of the molecular mechanism underlying the response of Lactiplantibacillus plantarum to lactic acid stress conditions

Heliyon, 2023
Lactic acid bacteria (LAB) present various benefits to humans; they play key roles in the fermentation of food and as probiotics. Acidic conditions are common to both LAB in the intestinal tract as well as fermented foods.
Ha-Young Jang, Min Ji Kim, Minseo Bae, In Min Hwang, Jong-Hee Lee   +4 more
doaj   +1 more source

Effect of lactid acid bacteria inoculants, formic acid, potassium sorbate and sodium benzoate on fermentation quality and aerobic stability of wilted grass silage [PDF]

, 2006
The efficiency of a novel strain of lactic acid bacteria inoculant (Lactobacillus plantarum VTT E-78076, E76) on the fermentation quality of wilted silage was studied.
Haikara, Auli, Jaakkola, Seija, Jalava, Taina, Saarisalo, Eeva, Skyttä, Eija   +4 more
core   +1 more source