Results 31 to 40 of about 347,998 (329)

Autophagy extends lifespan via vacuolar acidification

Microbial Cell, 2014
Methionine restriction (MetR) is one of the rare regimes that prolongs lifespan across species barriers. Using a yeast model, we recently demonstrated that this lifespan extension is promoted by autophagy, which in turn requires vacuolar acidification ...
Christoph Ruckenstuhl, Christine Netzberger, Iryna Entfellner, Didac Carmona-Gutierrez, Thomas Kickenweiz, Slaven Stekovic, Christina Gleixner, Christian Schmid, Lisa Klug, Ivan Hajnal, Alice G. Sorgo, Tobias Eisenberg, Sabrina Büttner, Guillermo Marino, Rafal Koziel, Christoph Magnes, Frank Sinner, Thomas R. Pieber, Pidder Jansen-Dürr, Kai-Uwe Fröhlich, Guido Kroemer, Frank Madeo   +21 more
doaj   +1 more source

Short-term Chronic Toxicity Tests on Acidified Lake Tazawa Using Responses of Three Trophic Levels of Aquatic Organisms

Journal of Water and Environment Technology, 2020
Lake Tazawa in Akita Prefecture, Japan, is an acidic lake caused by the inflow of low-pH water from Tamagawa Hot Springs. Because of this anthropogenic acidification, many indigenous fish species and aquatic ecosystem have perished.
Juhyun Kim, Shuhei Masuda, Shigeki Harada, Osamu Nishimura   +3 more
doaj   +1 more source

Ongoing transients in carbonate compensation [PDF]

, 2010
Uptake of anthropogenic CO2 is acidifying the oceans. Over the next 2000 years, this will modify the dissolution and preservation of sedimentary carbonate.
Andreas F. Hofmann, Archer, Archer, Archer, Archer, Archer, Bernard P. Boudreau, Berner, Boudreau, Boudreau, Broecker, Broecker, Broecker, Broecker, Broecker, Caldeira, Filip J. R. Meysman, Gehlen, Gruber, Jack J. Middelburg, Keir, Key, Khatiwala, Knox, Lane, Lenton, Merico, Millero, Munhoven, Oxburgh, Ridgwell, Ridgwell, Ridgwell, Riebesell, Roberts, Sarmiento, Sarmiento, Siegenthaler, Stephens, Toggweiler, Wigley, Zeebe, Zeebe   +42 more
core   +2 more sources

Acidification

, 2015
Contains fulltext : 151108.pdf (Publisher’s version ) (Open Access)
Zelm, R. van, Roy, P.-O., Hauschild, M., Huijbregts, M.A.J.   +3 more
openaire   +2 more sources

Acid-sensing ion channels 1a (ASIC1a) inhibit neuromuscular transmission in female mice [PDF]

, 2014
Acid-sensing ion channels (ASIC) open in response to extracellular acidosis. ASIC1a, a particular subtype of these channels, has been described to have a postsynaptic distribution in the brain, being involved not only in ischemia and epilepsy, but also ...
Colettis, Natalia Claudia, Gonzalez, Laura Elisabeth, González Inchauspe, Carlota María Fabiola, Lino, Noelia Gisele, Uchitel, Osvaldo Daniel, Urbano Suarez, Francisco Jose, Vattino, Lucas Gabriel, Wemmie, John A., Wunsch, Amanda M.   +8 more
core   +1 more source

Nouvelle méthode rapide de dosage du gaz carbonique dans les vins tranquilles

OENO One, 1982
Le dosage du gaz carbonique du vin est possible par déplacement du gaz par acidification et mesure de la variation de conductivité d'un thermistor. L'appareil CORNING 965 D permet un dosage très rapide, reproductible, impersonnel et équivalent à la ...
Jacques Blouin, Alain Desenne
doaj   +1 more source

Nucleolipid Acid-Based Nanocarriers Restore Neuronal Lysosomal Acidification Defects

Frontiers in Chemistry, 2021
Increasing evidence suggests that lysosomal dysfunction has a pathogenic role in neurodegenerative diseases. In particular, an increase in lysosomal pH has been reported in different cellular models of Parkinson’s disease.
Mathias Brouillard, Philippe Barthélémy, Benjamin Dehay, Sylvie Crauste-Manciet, Sylvie Crauste-Manciet, Valérie Desvergnes   +5 more
doaj   +1 more source

Ocean acidification

Choice Reviews Online, 2012
Increasing atmospheric CO2 concentration is causing increased absorption of CO2 by the world’s oceans, in turn driving a decline in seawater pH and changes in ocean carbonate chemistry that are collectively referred to as ocean acidification. Evidence is accumulating to suggest ocean acidification may directly or indirectly affect many marine organisms
Howard, William R., Nash, Merinda, Anthony, Ken, Schmutter, Katherine, Bostock, Helen, Bromhead, Donald, Byrne, Maria, Currie, Kim, DiazPulido, Guillermo, Eggins, Stephen, Ellwood, Michael, Eyre, Bradley, Haese, Ralf, Hallegraeff, Gustaaf, Hill, Katy, Hurd, Catriona, Law, Cliff, Lenton, Andrew, Matear, Richard, McNeil, Ben, McCulloch, Malcolm, Müller, Marius N., Munday, Philip, Opdyke, Bradley, Pandolfi, John M., Richards, Russell, Roberts, Donna, Russell, Bayden D., Smith, Abigail M., Tilbrook, Bronte, Waite, Anya, Williamson, Jane   +31 more
  +5 more sources

High CO2 decreases the long-term resilience of the free-living coralline algae Phymatolithon lusitanicum [PDF]

, 2018
Maerl/rhodolith beds are protected habitats that may be affected by ocean acidification (OA), but it is still unclear how the availability of CO2 will affect the metabolism of these organisms.
Amado-Filho, Boyd, Boyd, Brodie, Burdett, Büdenbender, Carro, Dickson, Dupont, Dupont, Egilsdottir, Frankignoulle, Gao, Gao, Gattuso, Gattuso, Heijden, Hofmann, Hurd, IPCC, IPCC, Johnson, Jokiel, Kamenos, Kamenos, Kroeker, Kroeker, Labasque, Lewis, Martin, Martin, Martin, McCoy, McCoy, McCoy, McCoy, Mehrbach, Nash, Noisette, Noisette, Peña, Ragazzola, Ragazzola, Ragazzola, Ritchie, Roleda, Sampath-Wiley, Short, Smith, Sordo, Steller, Torres, Vásquez-Elizondo, Williamson, Wolf-Gladrow, Yildiz   +55 more
core   +1 more source

The paradox between resistance to hypoxia and liability to hypoxic damage in hyperglycemic peripheral nerves. Evidence for glycolysis involvement [PDF]

, 1993
Isolated ventral and dorsal rat spinal roots incubated in normal (2.5 mM) or high glucose (25 mM) concentrations or in high concentrations of other hexoses were exposed transiently to hypoxia (30 min) in a solution of low buffering power.
Grafe, Peter, Niedermeier, W., Schneider, Uwe   +2 more
core   +1 more source