Results 101 to 110 of about 64,694 (238)
Lactate-proton co-transport and its contribution to interstitial acidification during hypoxia in isolated rat spinal roots [PDF]
, 1993 Exposure of nervous tissue to hypoxia results in interstitial acidification. There is evidence for concomitant decrease in extracellular pH to the increase in tissue lactate.
Aronson +45 more
core +1 more source
Nano Delivery Strategy Opens Effective Avenues for the Treatment of Colorectal Cancer
Medicine Bulletin, EarlyView.ABSTRACT Colorectal cancer (CRC) presents significant therapeutic challenges because of chemoresistance, systemic toxicity, and the complexity of the tumor microenvironment (TME). Nanodrug delivery systems (NDDS) have emerged as versatile platforms capable of overcoming these limitations by enhancing tumor accumulation, improving pharmacokinetics, and ...
Qiurong Wei +7 more
wiley +1 more source
Feed intake pattern, behaviour, rumen characteristics and blood metabolites of finishing beef steers offered total mixed rations constituted at feeding or ensiling [PDF]
, 2009 peer-reviewedTwo experiments were undertaken. In Experiment 1, behaviour, intake pattern and blood metabolites, were recorded for steers offered total mixed rations (TMR) based on grass silage and concentrates, and constituted either at ensiling (E-TMR)
Cummins, B. +3 more
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Nutrition in Clinical Practice, EarlyView.Abstract Background Although previous experimental studies showed that metabolic acidosis promoted muscle catabolism and impaired protein synthesis, few epidemiological studies reported an independent association between serum bicarbonate levels and muscle atrophy in patients with chronic kidney disease (CKD).
Nobuhisa Morimoto +13 more
wiley +1 more source
Hyperglycaemia does not increase perfusion deficits after focal cerebral ischaemia in male Wistar rats [PDF]
, 2018 Background: Hyperglycaemia is associated with a worse outcome in acute ischaemic stroke patients; yet the pathophysiological mechanisms of hyperglycaemia-induced damage are poorly understood.
Dewar, Deborah +5 more
core +1 more source
Anaesthesia, EarlyView.Summary Introduction Surgery in patients with diabetes mellitus is associated with increased morbidity and mortality compared with those who do not have diabetes mellitus. This is likely multifactorial and could be attributed to organisational issues; dysglycaemia; hospital‐acquired diabetic ketoacidosis; errors with insulin prescribing and ...
Nicholas A. Levy +19 more
wiley +1 more source
Throat and rectal swabs may have an important role in MRSA screening of critically ill patients.
, 2008 OBJECTIVE: Methicillin-resistant Staphylococcus aureus (MRSA) is a major problem in intensive care units (ICU). International guidelines recommend screening patients for MRSA on admission, although consensus on sites required for optimum detection has ...
Batra, Rahul +3 more
core +1 more source
Vitamin B1 for type B metabolic acidosis: An underrecognized approach
Saudi Journal of Kidney Diseases and Transplantation, 2018 Lactic acidosis is a life-threatening and rather common complication and reason for consultation to the nephrologist. The cause for this condition is usually thought to be secondary to hypoperfusion and ischemia collectively.
Adriana Dejman, Jason Riveros
doaj +1 more source
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aims Evogliptin, a dipeptidyl peptidase‐4 inhibitor with a glucose‐dependent mechanism of action, is widely used as a monotherapy or in combination with other agents. However, observational studies in routine clinical settings remain limited.
Jun Hwa Hong +14 more
wiley +1 more source
The Effects of Pre and Post Exercise Low-Level Laser Therapy on Biochemical Markers of Skeletal Muscle Fatigue in Equines [PDF]
, 2019 Our objective was to determine whether administering low-level laser therapy before or after exercise had the greatest effect on biochemical markers of skeletal muscle fatigue in equines such as cortisol and blood lactate.
Freeman, Carson
core +2 more sources