Results 131 to 140 of about 64,694 (238)

Adjunctive interferon-γ immunotherapy for the treatment of HIV-associated cryptococcal meningitis: a randomized controlled trial.

, 2012
BACKGROUND: Interferon-gamma (IFNγ) is of key importance in the immune response to Cryptococcus neoformans. Mortality related to cryptococcal meningitis remains high, and novel treatment strategies are needed.
Bekker, Linda-Gail, Bicanic, Tihana, Harrison, Thomas S, Jarvis, Joseph N, Meintjes, Graeme, Rebe, Kevin, Schutz, Charlotte, Williams, Anthony, Williams, Gertrude Ntombomzi, Wood, Robin   +9 more
core   +1 more source

Alkaline Phosphatase‐Activated NIR‐II AIEgens Nanosystem for Surgical and Postoperative Closed‐Loop Therapy of Advanced Osteosarcoma

Advanced Science, Volume 13, Issue 16, 18 March 2026.
This study designed a tumor microenvironment‐responsive AIEgen nanoparticle for near‐infrared photoimmunotherapy, which inhibits primary tumors and metastasis by promoting pyroptosis and suppressing aerobic glycolysis. ABSTRACT In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's ...
Kaiyuan Liu, Ruotong Li, Li Zhang, Hengli Lu, Binhui Yang, Qian Hu, Yining Tao, Haoran Mu, Jing Han, Pengfei Zan, Jiakang Shen, Dongqing Zuo, Hongsheng Wang, Wei Sun, Xingjun Zhu   +14 more
wiley   +1 more source

In Vitro Fermentation Characteristics and Rumen Microbial Population of Diet Supplemented with Saccharomyces Cerevisiae and Rumen Microbe Probiotics [PDF]

, 2016
The objective of this study was to select three strains of probiotic Saccharomyces cerevisiae and to evaluate the effect of S. cerevisiae and rumen bacteria isolate (MR4) supplementation and their combination on rumen fermentability and rumen microbial ...
Evvyernie, D. (Dwierra), Riyanti, L. (Lilis), Suryahadi, S. (Suryahadi)   +2 more
core  

Attenuated Bacteria‐Based Tumor Therapy: Clinical Application Risks, Marketing Approval Restrictions, and Coping Strategies

Advanced Science, Volume 13, Issue 16, 18 March 2026.
This review comprehensively overviews attenuated bacteria‐based tumor therapy, highlighting key methodologies and recent progress. It examines strategies for enhancing safety, stabilizing efficacy, optimizing manufacturing, and navigating regulatory pathways.
Yucheng Liu, Junhong Yao, Jiaxin Deng, Minjie Zhou, Kaiyue Shen, Shishuo Sun, Xiaoge Gao, Qing Zhang, Haiheng Xu   +8 more
wiley   +1 more source

An Infant With Phakomatosis Pigmentovascularis Complicated by Multisystem Damage: Elaborate Care Leads to a Positive Outcome

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT This report highlights the value of multidisciplinary collaboration, personalized care, dynamic monitoring of seizure activity, and innovative skin management in a 2‐month‐old with Phakomatosis Pigmentovascularis. In parallel, the nursing team implemented a multidimensional “medical–social–psychological” support model, providing psychological ...
Kaimin Chen, Xiaoxia Huang, Xin Jin, Lilan He, Mingzhu He, Wenli Shen, Yuling Zheng   +6 more
wiley   +1 more source

Thiamine deficiency-related myocardial dysfunction: A hidden cause of refractory lactic acidosis and shock in severe diabetic ketoacidosis: A case report

Journal of Pediatric Critical Care
Diabetic ketoacidosis (DKA) is a life-threatening complication of diabetes mellitus, characterized by hyperglycemia, ketosis, and metabolic acidosis. Severe dehydration and hypovolemic shock in severe DKA are common, but myocardial dysfunction and lactic
Sannarudrappa Sagar, Namita Ravikumar, B. M. Sunil Kumar, V. Subrahmanya Murti   +3 more
doaj   +1 more source

Toxic alcohols [PDF]

, 2018
Kraut, Jeffrey A, Mullins, Michael E
core   +2 more sources

Lactic acidosis. [PDF]

BMJ, 1971
K G, Alberti, J, Corbett, T D, Hockaday, D H, Williamson   +3 more
openaire   +4 more sources

Renal Protection at a Metabolic Cost: A Systematic Review and Meta‐Analysis of Perioperative Use of Sodium–Glucose Cotransporter 2 Inhibitors

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 2, March 2026.
Across 246,542 surgical patients, perioperative SGLT2 inhibitor use was associated with a lower odds of acute kidney injury and mortality. In contrast, ketoacidosis outcomes (DKA and euglycemic ketoacidosis) showed no statistically significant difference overall, but appeared more frequent in selected sensitivity and subgroup analyses, consistent with ...
Elsayed Balbaa, Ahmed Farid Gadelmawla, Ahmed Ibrahim, AlMothana Manasrah, Ahmed Elbataa, Abdalhakim Shubietah, Mohamed S. Elgendy, Ahmed Sobhy, Ahmed Mansour, Ameer Awashra, Nourhan N. Elguindy, Mohammad Bazzazeh, Abdelhamid Ben‐Selma   +12 more
wiley   +1 more source

Impact of Short‐Term Insulin Pump Therapy on Cardiometabolic Index in Patients With Newly Diagnosed Type 2 Diabetes Mellitus

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 2, March 2026.
The study reveals that CMI levels significantly decrease after short‐term CSII therapy in T2DM, with CMI positively correlated with insulin resistance, indicating the therapy's significance in improving patients' cardiometabolic function. ABSTRACT Objective This study aims to investigate the changes in cardiometabolic index (CMI) levels in newly ...
Xia Chen, Shuya Li, Zeren Chen, Dong Wang, Ling Yang, Xia Deng, Haoxiang Li   +6 more
wiley   +1 more source