Results 21 to 30 of about 134,882 (291)
Neurodegenerative Disease: What Potential Therapeutic Role of Acid-Sensing Ion Channels?
Frontiers in Cellular Neuroscience, 2021 Acidic pH shift occurs in many physiological neuronal activities such as synaptic transmission and synaptic plasticity but also represents a characteristic feature of many pathological conditions including inflammation and ischemia.
Dalila Mango +3 more
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Replacing sodium bicarbonate with half amount of calcareous marine algae in the diet of beef cattle
Revista Brasileira de Zootecnia, 2019 This study evaluated the effects of feeding calcareous marine algae or sodium bicarbonate as rumen buffer on the performance, behaviour, in vitro diet digestibility, and meat quality of beef cattle.
Carlo Angelo Sgoifo Rossi +6 more
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pHLuc, a Ratiometric Luminescent Reporter for in vivo Monitoring of Tumor Acidosis
Frontiers in Bioengineering and Biotechnology, 2020 Even under normoxia, cancer cells exhibit increased glucose uptake and glycolysis, an occurrence known as the Warburg effect. This altered metabolism results in increased lactic acid production, leading to extracellular acidosis and contributing to ...
Tiffany T. Ong +5 more
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Normal Acid Base Balance in aluminum phosphide poisoning: Case reports of a rare presentation [PDF]
Asia Pacific Journal of Medical Toxicology, 2023 Introduction: Aluminum phosphide (AlP) is an effective fumigant and rodenticide which is a commonly used agent for suicide in parts of developing countries.
Ali Saffaei +4 more
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Romanian Journal of Laboratory Medicine, 2021 Introduction: The aim of the study is to present a case study of a 63-year-old male with pseudohyponatremia, falsely increased serum osmolal gap and severe metabolic acidosis.
Šálek Tomáš
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Carbonic anhydrase 12 mutation modulates membrane stability and volume regulation of aquaporin 5
Journal of Enzyme Inhibition and Medicinal Chemistry, 2019 Patients carrying the carbonic anhydrase12 E143K mutation showed the dry mouth phenotype. The mechanism underlying the modulation of aquaporin 5 and function in the salivary glands by carbonic anhydrase12 remains unknown. In this study, we identified the
Soyoung Hwang +4 more
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Frontiers in Physiology, 2022 BackgroundThe mortality of trauma combined with seawater immersion is higher than that of land injury, however, research on how to treat this critical case and which treatments to adopt is lacking.MethodsThe effect of the thiol compound, N-acetyl-L ...
Yiyan Liu +6 more
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Frontiers in Pharmacology, 2022 Acidosis is a hallmark of ischemic stroke and a promising neuroprotective target for preventing neuronal injury. Previously, genetic manipulations showed that blockade of acid-sensing ion channel 1a (ASIC1a)-mediated acidotoxicity could dramatically ...
Xin Qi +19 more
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Biochemical Markers as Predictors of In-Hospital Mortality in Patients with Severe Trauma: A Retrospective Cohort Study [PDF]
Korean Journal of Critical Care Medicine, 2017 Background Initial evaluation of injury severity in trauma patients is an important and challenging task. We aimed to assess whether easily measurable biochemical parameters (hemoglobin, pH, and prothrombin time/international normalized ratio [PT/INR ...
Ha Nee Jang +10 more
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