Results 41 to 50 of about 965 (148)

Metabolic Behaviors of Aconitum Alkaloids in Different Concentrations of Aconiti Lateralis Radix Praeparata and Effects of Aconitine in Healthy Human and Long QT Syndrome Cardiomyocytes

Molecules, 2022
Aconiti Lateralis Radix Praeparata (Fu Zi) is the processed lateral root of Aconitum carmichaelii Debx, which is widely used in emergency clinics. Poisoning incidents and adverse reactions occur with the improper intake of Fu Zi.
Liang Yang, Guanghui Xie, Yuguang Wang, Jian Li, Bin Zheng, Jinmiao Zhu, Xinsong Yuan, Qian Hong, Zengchun Ma, Yue Gao   +9 more
doaj   +1 more source

Components and Pharmacodynamical Mechanism of Yinfupian Based on Liquid Chromatography-Mass Spectrometry and Proteomics Analyses

Frontiers in Pharmacology, 2021
Objective: According to the treatment records of Yang deficiency syndrome (YDS) with characteristic decoction pieces of lateral root of Aconitum carmichaelii—Yinfupian (YF) in traditional Chinese medicine prepare school, known as “Jianchangbang”. The aim
Heng-li Tong, Hao Chen, Fei-peng Gong, Ling-yun Zhong, Jing Zhu, Song-hong Yang   +5 more
doaj   +1 more source

Antitumor effects and potential mechanisms of aconitine based on preclinical studies: an updated systematic review and meta-analysis

Frontiers in Pharmacology, 2023
Background: Herbs originating from the Aconitum L. (Ranunculaceae), such as Aconitum carmichaelii Debeaux. (Wutou), Aconitum pendulum Busch. (Tiebangchui), and Aconitum kusnezoffii Reichb. (Caowu), etc.
Gelin Xiang, Gelin Xiang, Nan Xing, Nan Xing, Shaohui Wang, Shaohui Wang, Yi Zhang, Yi Zhang   +7 more
doaj   +1 more source

Antiviral activity of aconite alkaloids from Aconitum carmichaelii Debx

Natural Product Research, 2017
Four diterpenoid alkaloids, namely, (a) hypaconitine, (b) songorine, (c) mesaconitine and (d) aconitine, were isolated from the ethanol root extract of Aconitum carmichaelii Debx. The antiviral activities of these alkaloids against tobacco mosaic virus (TMV) and cucumber mosaic virus (CMV) were evaluated.
Weiming, Xu, Min, Zhang, Hongwu, Liu, Kun, Wei, Ming, He, Xiangyang, Li, Deyu, Hu, Song, Yang, Yuguo, Zheng   +8 more
openaire   +2 more sources

Talatisamine, a C19-diterpenoid alkaloid from Chinese traditional herbal `Chuanwu'

Acta Crystallographica Section E, 2011
The title compound [systematic name: (1S,4S,5R,7S,8S,9R,10R,11S,13S,14S,16S,17R)-N-methyl-8,14-dihydroxy-1,16-trimethoxy-4-(methoxymethylene)aconitane], C24H39NO5, was isolated from the roots of Aconitum carmichaelii Debx., which is known as `Chuanwu' in
Jun Lei, Ya-Jun Luo, Qing-Quan Bian, Xiong-Qing Wang   +3 more
doaj   +1 more source

The complete chloroplast genome sequence of Aconitum tschangbaischanense (Ranunculaceae)

Mitochondrial DNA. Part B. Resources, 2023
The perennial herbal medicine species Aconitum tschangbaischanense, is endemic to Changhai Mountain, Jilin province. In this study, we attempted to uncover the complete chloroplast (cp) genome of A.
Xuelian Liu, Junyi Zhu, Mingge Jiang, Shengchao Guan, Liqiu Zhang, Haiying Zhao   +5 more
doaj   +1 more source

Quantitative 2D Nuclear Magnetic Resonance of Complex Mixtures: From General Analytical Homo/Heteronuclear Methods to Intrinsically Quantitative HSQC Approaches

Chemistry–Methods, Volume 6, Issue 7, July 2026.
Quantitative 2D nuclear magnetic resonance methods provide accurate individual analyte concentrations in complex mixtures. This review provides a unified description and comparison of such methods, together with an overview of applications and practical implementation tips. Quantitative 2D nuclear magnetic resonance (NMR) spectroscopy has emerged as an
Jérémy Marchand, Estelle Martineau, Jonathan Farjon, Patrick Giraudeau   +3 more
wiley   +1 more source

Yougui Pills Alleviate Osteoporosis by Inhibiting Mesenchymal Stem Cell ROS Accumulation via the Nrf2/HO‐1 Pathway

Journal of Cellular and Molecular Medicine, Volume 30, Issue 14, July 2026.
ABSTRACT Osteoporosis (OP) is a prevalent skeletal disorder characterized by progressive bone mass loss and deteriorated microarchitecture, in which oxidative stress‐induced mesenchymal stem cell (MSC) dysfunction serves as a core pathogenic mechanism. Yougui Pills (YGPs), a classical traditional Chinese medicine formula, are widely applied in clinical
Jiangyuan Liu, Kairui Chen, Jingyuan Wen, Qinghe Zeng, Liangyan Cheng, Qinwen Ge, Jiali Chen, Wenhua Yuan, Pinger Wang, Luwei Xiao, Hongting Jin, Yungang Wu   +11 more
wiley   +1 more source

Pharmacological effects, molecular mechanisms, and pharmacokinetics of benzoylaconine: a systematic review

Frontiers in Pharmacology
Benzoylaconine (BAC), a key active metabolite in traditional Chinese medicine, is derived from the subsoil roots of Fuzi (Aconitum carmichaelii Debx [Ranunculaceae, Aconitum carmichaelii Debx roots]).
Huamei Zhuang, Huamei Zhuang, Hong Yao, Hong Yao   +3 more
doaj   +1 more source

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

Ibrain, Volume 12, Issue 1, Page 65-85, Spring 2026.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source