Results 61 to 70 of about 965 (148)

Pharmacokinetics of 10-Hydroxy Mesaconitine in Rat Plasma by Ultra-Performance Liquid Chromatography-Tandem Quadrupole Mass Spectrometry

Journal of Analytical Methods in Chemistry, 2021
Mesaconitine is the predominant active ingredient in Aconitum carmichaelii Debx. The compound 10-hydroxy mesaconitine is one known metabolite of mesaconitine and is toxic.
Jinzhao Yang, Guowu Zeng, Jianshe Ma, Xianqin Wang, Quan Zhou   +4 more
doaj   +1 more source

Assembling genomes of non‐model plants: A case study with evolutionary insights from Ranunculus (Ranunculaceae)

The Plant Journal, Volume 123, Issue 6, September 2025.
SUMMARY Whereas genome sequencing and assembly technologies are improving, cost can still be prohibitive for plant species with large, complex genomes. As a consequence, genomics work on some taxa in evolutionarily pivotal positions in the vascular plant tree of life has been hampered.
Kevin Karbstein, Nancy Choudhary, Ting Xie, Salvatore Tomasello, Natascha D. Wagner, Birthe H. Barke, Claudia Paetzold, John P. Bradican, Michaela Preick, Axel Himmelbach, Nils Stein, Argyris Papantonis, Iker Irisarri, Jan de Vries, Boas Pucker, Elvira Hörandl   +15 more
wiley   +1 more source

Research progress on traditional Chinese medicine animal models of post‐stroke depression and pathological insights

Animal Models and Experimental Medicine, Volume 8, Issue 8, Page 1387-1399, August 2025.
Post‐stroke depression (PSD) animal model of traditional Chinese medicine (TCM) combined with disease and syndrome often uses western medicine surgery (including: middle cerebral artery embolization to construct cerebral ischemia, or brain injection of collagenase to construct cerebral hemorrhage) combined with other methods (including: isolation ...
Jielin Wang, Wenlu Ma, Wei Wu, Yujuan Fu, Hui Li   +4 more
wiley   +1 more source

A Case of Severe Anemia in Pregnancy Treated With Traditional Chinese Medicine

Clinical Case Reports, Volume 13, Issue 8, August 2025.
ABSTRACT This case report describes the treatment of a 29‐year‐old pregnant woman with severe anemia using traditional Chinese medicine (TCM). The patient, at 5 weeks of gestation, presented with a hemoglobin level of 75 g/L and had a history of autoimmune hemolytic anemia and alpha‐thalassemia, which had previously led to pregnancy termination at 17 ...
Suqin Zhong, Ting Xie
wiley   +1 more source

Application of Veno‐Arterial ECMO Combined With Hemoperfusion in the Treatment of a Patient With Yunaconitine Poisoning: A Case Report

Annals of Noninvasive Electrocardiology, Volume 30, Issue 2, March 2025.
A 40‐year‐old male with severe aconitine poisoning underwent VA‐ECMO and hemoperfusion, leading to arrhythmia control and improved cardiac function. This case highlights the effectiveness of combined treatments in severe poisoning cases without specific antidotes.
Zhuo Jiang, Yue Zhuang, Xueting Hu, Wei Chen, Fei Xia, Xiaoxia Hu, Aixiang Yang, Weiyi Tao   +7 more
wiley   +1 more source

Genetic diversity and marker–trait association analysis for agronomic traits in Aconitum carmichaelii Debeaux

Biotechnology & Biotechnological Equipment, 2017
The root of Aconitum carmichaelii Debeaux is used in Oriental folk medicine, but its cultivation is very labour intensive. Therefore, it is important to dissect the genetic mechanism of agronomic traits to breed elite cultivars for commercial cultivation.
Ma Yu, Ling-Li Cao, Yu-Xia Yang, Ling-Liang Guan, Lu-Lu Gou, Xiao-Yan Shu, Jing Huang, Dan Liu, Hong Zhang, Da-Bin Hou   +9 more
doaj   +1 more source

Preventive Effect of Shenfu Injection on Arrhythmia After Percutaneous Coronary Intervention in Patients With ST‐Segment Elevation Myocardial Infarction: A Prospective Randomized Controlled Trial

Cardiovascular Therapeutics, Volume 2025, Issue 1, 2025.
Background and Aims Arrhythmias and major adverse cardiac events remain significant complications following ST‐segment elevation myocardial infarction (STEMI). Shenfu injection, a traditional Chinese medicine formulation, has shown cardioprotective effects in preclinical studies.
Xiaohan Qiu, Yue Wang, Jiahan Ke, Min Wang, Huasu Zeng, Huafang Zhu, Jun Gu, Hangang Yu   +7 more
wiley   +1 more source

ZIF‐8 Selective Dispersive Solid‐Phase Extraction‐LC‐MS/MS Method for the Determination of Aconitine alkaloids in Rat Plasma: Application in Pharmacokinetic Studies

Journal of Analytical Methods in Chemistry, Volume 2025, Issue 1, 2025.
Objective: Aconitine alkaloids, as the principal bioactive constituents of Fuzi, pose a significant challenge to its clinical application due to their toxicity. This study aimed to establish a rapid, efficient, and stable method for quantifying monoester‐type and diester‐type alkaloids in raw Fuzi using zeolitic imidazolate framework‐8 (ZIF‐8).
Yang Yang, Liu Renyan, Xin Lingyi, Feng Baodong, Zhang Yu, Su Linqi, Ming Tingwen, Liu Jingjian, Chen Qinhua, Adrián Gutiérrez-Serpa   +9 more
wiley   +1 more source

EXPRESSION OF CONCERN: The Cardiovascular Protective Function of Natural Compounds Through AMPK/SIRT1/PGC‐1α Signaling Pathway

Food Science &Nutrition, Volume 12, Issue 12, Page 9998-10009, December 2024.
Cardiovascular disease (CVD) is a major threat to human health and imposes a heavy burden on individuals, society, and healthcare systems. A key goal of our search was to find natural compounds that target this biological pathway and have beneficial effects on CVD.
Sohrab Rahmani, Ali Roohbakhsh, Vahid Pourbarkhordar, Gholamreza Karimi   +3 more
wiley   +1 more source

Matrix Metalloproteinases on Skin Photoaging

Journal of Cosmetic Dermatology, Volume 23, Issue 12, Page 3847-3862, December 2024.
ABSTRACT Background Skin aging is characterized by an imbalance between the generation and degradation of extracellular matrix molecules (ECM). Matrix metalloproteinases (MMPs) are the primary enzymes responsible for ECM breakdown. Intrinsic and extrinsic stimuli can induce different MMPs.
Chao Feng, Xianglong Chen, Xiuqing Yin, Yanfei Jiang, Chunyue Zhao   +4 more
wiley   +1 more source