Results 81 to 90 of about 1,015 (136)

Potentially Cardiotoxic Diterpenoid Alkaloids from the Roots of Aconitum carmichaelii

, 2019
Aconitum carmichaelii is a traditional Chinese herbal medicine used for the treatment of pain and inflammation in the joints. However, the strong cardiotoxicity hinders its use.
Na Li (6550), Liang Liu (50022), Zhongqiu Liu (50019), Hua Zhou (50017), Xingxing Zong (6491099), Jian-Lin Wu (2707027), Xiaojing Yan (223994)   +6 more
core   +1 more source

Fucoidan Alleviates Colitis and Metabolic Disorder by Protecting the Intestinal Barrier, Suppressing the MAPK/NF‐κB Pathways, and Regulating the Gut Microbiota

Journal of Food Biochemistry, Volume 2024, Issue 1, 2024.
Scytosiphon lomentaria is widely consumed in China’s coastal regions due to its various beneficial effects, although its exact mechanism has yet to be fully elucidated. This study demonstrated that S. lomentaria fucoidan (SLF) alleviated colitis symptoms in mice, as evidenced by a reduction in colonic tissue damage and an increase in colon length and ...
Shuangru Tang, Lu Wang, Xiaomeng Ren, Shuang Song, Chunqing Ai, Kai Wang   +5 more
wiley   +1 more source

Involvement of autophagy in mesaconitine-induced neurotoxicity in HT22 cells revealed through integrated transcriptomic, proteomic, and m6A epitranscriptomic profiling

Frontiers in Pharmacology
Background: Mesaconitine (MA), a diester-diterpenoid alkaloid extracted from the medicinal herb Aconitum carmichaelii, is commonly used to treat various diseases. Previous studies have indicated the potent toxicity of aconitum despite its pharmacological
Xiaohuang Lin, Jian Zhang, Jian Zhang, Zekai Wu, Yuan Shi, Mengting Chen, Maodong Li, Hong Hu, Kun Tian, Xiaoqi Lv, Chutao Li, Yang Liu, Xinyue Gao, Qiaomei Yang, Kunqi Chen, An Zhu   +15 more
doaj   +1 more source

Aconicatisulfonines A and B, Analgesic Zwitterionic C₂₀-Diterpenoid Alkaloids with a Rearranged Atisane Skeleton from Aconitum carmichaelii

, 2019
Two sulfonated C20-diterpenoid alkaloid iminiums with a novel skeleton, named aconicatisulfonines A (1) and B (2), respectively, were isolated from a water extract of the Aconitum carmichaelii lateral roots.
Jiangong Shi (426279), Yuzhuo Wu (7299536), Tiantai Zhang (4762650), Qinglan Guo (477828), Shuai Shao (1415941), Huan Xia (397709), Chengbo Xu (6295682)   +6 more
core   +1 more source

Advances for anti-inflammatory ingredients and activities of Fuzi (lateral root of Aconitum carmichaelii Debx.)

, 2023
The rising prevalence and detrimental impact of inflammatory diseases have spurred the exploration of novel therapeutic approaches to tackle these conditions. Fuzi, lateral root of Aconitum carmichaelii Debx.
Yuxin Zhang (168579), Weiwei Zhou (583665), Zufeng Zhang (17678655), Junyu Mou (17678658), Ling Liu (143030), Yuanyuan Hu (110767), Xuefeng Wang (113961), Wei Zheng (25452)   +7 more
core   +1 more source

Diterpenoid Alkaloids from the Lateral Root of Aconitum carmichaelii

, 2016
Twenty-six new diterpenoid alkaloids, 1–26 (1–4: hetisan-type C20-diterpenoid alkaloids; 5–26: aconitane C19-diterpenoid alkaloids), and two known analogues, hypaconitine 27 and benzoylmesaconine 28, have been isolated from a water extract of the ...
Sujuan Wang (1865149), Jianjun Zhang (220300), Jiangong Shi (426279), Naihong Chen (549471), Minghua Chen (1708423), Sheng Lin (348211), Yongchun Yang (432280), Jinfeng Hu (2071654), Chenggen Zhu (1771843), Yanan Wang (123548), Bingya Jiang (1744837)   +10 more
core   +1 more source

Data_Sheet_1_Characteristics of Isolates of Pseudomonas aeruginosa and Serratia marcescens Associated With Post-harvest Fuzi (Aconitum carmichaelii) Rot and Their Novel Loop-Mediated Isothermal Amplification Detection Methods.docx

, 2021
Fuzi (the lateral root of Aconitum carmichaelii Debx.) is a traditional Chinese medicine that is cultivated in more than eight provinces in China. However, it can be easily devastated by post-harvest rot, causing huge losses.
Xin Zhang (35492), Bei Chen (202271), Langjun Cui (11304939), Mingzhu Li (685750), Guoyan Zhang (2203600), Meng Fu (307487)   +5 more
core   +1 more source

EFFECTS OF CULTURE TEMPERATURE ON MICROTUBER FORMATION OF ACONITUM CARMICHAELII DEBX. AND ACONITINE-TYPE ALKALOID CONTENTS

, 1998
The clonally propagated Aconitum carmichaelii Debx. was used for the investigation of microtubering. The rooting condition of propagated shoots affected the establishment of transplantation to soil indicating the Murashige-Skoog medium supplemented with ...
Shiping, C., Shoyama, Y., Tanaka, H., 正山, 征洋, Shan, S.J.   +4 more
core  

Aconitum carmichaelii: a clinical-regulatory synthesis of traditional use, toxicological evidence, and global safety governance

Frontiers in Pharmacology
Aconitum carmichaelii Debeaux (Ranunculaceae), commonly used as Aconiti Lateralis Radix Praeparata (Fuzi), is a clinically important but highly toxic herb in traditional Chinese medicine.
Ru Ya Tan, Pin Jun Ooi, Xiangyang Xu, Xu Wei, Xu Wen, Qiyue Qiu, Mun Fei Yam, Mun Fei Yam   +7 more
doaj   +1 more source

Processed lateral root of Aconitum carmichaelii Debx.: A review of cardiotonic effects and cardiotoxicity on molecular mechanisms. [PDF]

Front Pharmacol, 2022
Zhang J, Li D, Zhong D, Zhou Q, Yin Y, Gao J, Peng C.   +6 more
europepmc   +1 more source