Results 51 to 60 of about 965 (148)

Reducing Neuroinflammation via Inhibition of Fibrinogen Deposition and Microglial Activation as an Underlying Mechanism of Paning I Decoction in Ameliorating Parkinson's Disease Symptoms

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
Paning I decoction alleviated neuroinflammation in Parkinson's disease. ABSTRACT Background Parkinson's disease (PD) is a major neurodegenerative disorder. Some patients show limited response to standard therapies, driving the need for new complementary treatments.
Yan‐Jun Chen   +8 more
wiley   +1 more source

Integrating Traditional Wisdom With Modern Science: Ginsenosides as Antiheart Failure Agents

open access: yesCardiovascular Therapeutics, Volume 2026, Issue 1, 2026.
Heart failure (HF), as the terminal stage of various cardiovascular diseases, remains a global health challenge with persistently high morbidity and mortality rates. Although current therapies—including angiotensin receptor–neprilysin inhibitors, sodium‐glucose cotransporter‐2 inhibitors, and cardiac resynchronization therapy—have improved outcomes ...
Li Zhou   +6 more
wiley   +1 more source

Chinese Herbal Medicines for Diabetic Cardio‐Cerebrovascular Diseases: Key Bioactive Metabolites and Action Mechanisms

open access: yesJournal of Nutrition and Metabolism, Volume 2026, Issue 1, 2026.
Currently, the global incidence of diabetes is increasing, particularly in populous developing regions. In China, over 290 million people are affected by diabetic cardio‐cerebrovascular diseases. These diseases account for more than 40% of deaths and impose a significant economic burden on both society and families.
Ying Su   +7 more
wiley   +1 more source

Identification of Anti‐Inflammatory and Analgesic Mechanisms of Naru‐3 Wei Pill Using Animal Models, UHPLC‐QE‐MS, and Integrated Network Pharmacology

open access: yesMediators of Inflammation, Volume 2026, Issue 1, 2026.
Background Naru‐3 Wei Pill is a traditional Mongolian Medicine (TMM) that has anti‐inflammatory, analgesic, and antibacterial effects. The present study aimed to demonstrate the anti‐inflammatory and analgesic effect of Naru‐3 Wei Pill, identify the core components and key targets and determine the pharmacological basis and mechanism of its blood‐borne
Zhiqiang Han   +11 more
wiley   +1 more source

New dianthramide and cinnamic ester glucosides from the roots of Aconitum carmichaelii

open access: yesJournal of Asian Natural Products Research, 2018
Four new compounds N-salicyl-3-hydroxyanthranilic acid methyl ester (1), N-(2′-dehydroxysalicyl)-3-hydroxyanthranilic acid methyl ester (2), methyl-4-β-D-allopyranosyl-ferulate (3), and methyl-4-β-D-gulopyranosyl-cinnamate (4), along with six known compounds (5–10), were isolated from the roots of Aconitum carmichelii Debx.
Thi Quynh, Do   +11 more
openaire   +2 more sources

Effective control of southern blight and root rot of Aconitum carmichaelii Debeaux by endophytic Bacillus velezensis YN-2-6S

open access: yesBiological Control
Southern blight and root rot were two main soil-borne diseases of Aconitum carmichaelii Debeaux, a famous medicinal plant rich in alkaloids. Beneficial microbe based biological control has been a promising and sustainable alternative for disease control.
Qian Wang   +7 more
doaj   +1 more source

Identification of antagonistic fungi and their antifungal activities against aconite root rot pathogens

open access: yesPlant Signaling & Behavior, 2023
Root rot is one of the main diseases affecting Aconitum carmichaelii Debx. during cultivation, seriously limiting yields of this herb. Currently, there is no effective control measure for aconite root rot.
Ran Liu   +4 more
doaj   +1 more source

Insights on neuropharmacological benefits and risks: Aconitum carmichaelii Debx.

open access: yesBiomedicine & Pharmacotherapy
Aconitum carmichaelii Debx., a traditional herb known for its potent bioactivities, has been widely used in Traditional Chinese Medicine, particularly in the forms of Chuanwu and Fuzi. Despite the therapeutic benefits of this plant, concerns have been raised regarding its neuropharmacological actions and potential neurotoxicity.
Xiuyun Liu   +8 more
openaire   +2 more sources

Herbal Medicine for Colorectal Cancer Treatment: Molecular Mechanisms and Clinical Applications

open access: yesCell Proliferation, Volume 58, Issue 10, October 2025.
Colorectal cancer is a prevalent gastrointestinal tumour and the second deadliest cancer worldwide, affecting approximately 10% of all cancers and cancer‐related deaths. Current clinical methods for treating CRC cause gastrointestinal abnormalities and myelosuppression.
Zuqing Su   +5 more
wiley   +1 more source

Preparative separation of C19-diterpenoid alkaloids from Aconitum carmichaelii Debx by pH‑zone-refining counter-current chromatography

open access: yesQuímica Nova, 2013
The technique of pH-zone-refining counter-current chromatography was successfully applied to preparatively separate three C19-diterpenoid alkaloids from the crude extracts of Aconitum carmichaelii for the first time using a two-phase solvent system of ...
Dahui Liu   +6 more
doaj   +1 more source

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