Results 51 to 60 of about 16,499 (185)

Targeting of the Essential acpP, ftsZ, and rne Genes in Carbapenem-Resistant Acinetobacter baumannii by Antisense PNA Precision Antibacterials

Biomedicines, 2021
Infections by carbapenem-resistant A. baumannii (CRAB), a widespread nosocomial pathogen, are becoming increasingly difficult to prevent and treat. Therefore, there is an urgent need for discovery of novel antibiotics against CRAB.
Alireza Japoni Nejad, Nader Shahrokhi, Peter E. Nielsen   +2 more
doaj   +1 more source

The Response Regulator YycF Inhibits Expression of the Fatty Acid Biosynthesis Repressor FabT in Streptococcus pneumoniae [PDF]

, 2016
The YycFG (also known as WalRK, VicRK, MicAB or TCS02) two-component system (TCS) is highly conserved among Gram-positive bacteria with a low G+C content.
Maria L. Mohedano, Mónica Amblar, Alicia de la Fuente, Jerry M. Wells, Paloma López   +4 more
core   +2 more sources

Metodología presencial y online en mediación familiar licitada en Chile y ACPP

Barataria. Revista Castellano-Manchega de Ciencias Sociales, 2023
El objetivo del presente artículo es comparar la calidad de los servicios de mediación familiar licitada en Chile desde un contexto presencial a la transición de un sistema online, debió ser implementado efecto de la pandemia de coronavirus. Una metodología cualitativa, comparativa y aplicada, observación del uso del instrumento ECAME, con un sistema ...
openaire   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

The high-precision, charge-dependent Bonn nucleon-nucleon potential (CD-Bonn)

, 2000
We present a charge-dependent nucleon-nucleon (NN) potential that fits the world proton-proton data below 350 MeV available in the year of 2000 with a chi^2 per datum of 1.01 for 2932 data and the corresponding neutron-proton data with chi^2/datum = 1.02
A. Ahmidouch, A. Holt, A. Nogga, A. Polls, B. Lorentz, B. v. Przewoski, B. W. Raichle, C. A. Davis, C. Caso, C. M. Vincent, C. R. Howell, C. van der Leun, D. Abbott, D. E. González Trotter, D. E. Groom, D. M. Bishop, E. E. Salpeter, F. Andreozzi, F. Andreozzi, F. Andreozzi, F. Gross, F. Rathmann, F. Sammarruca, F. Sammarruca, F. Schmidt-Kaler, G. A. Miller, G. A. Miller, G. Breit, G. E. Brown, G. J. M. Austin, G. Krein, G. Q. Li, G. Q. Li, G. Rupp, H. Arenhövel, H. B. O’Connell, H. B. O’Connell, H. Dombrowski, H. Müther, H. P. Stapp, J. A. Nolen, J. Ball, J. Ball, J. Blatt, J. Brož, J. Brož, J. Carbonell, J. Franz, J. Goetz, J. L. Friar, J. Martorell, J. Piekarewicz, J. R. Bergervoet, J. R. Bergervoet, J. Rahm, J. Suhonen, K. Erkelenz, K. Holinde, K. Pachucki, L. Coraggio, L. Engvik, L. Koester, L. Tiator, M. Abramowitz, M. F. Jiang, M. Haftel, M. Jacob, M. Kirchbach, M. Lacombe, M. M. Pavan, N. L. Rodning, O. Dumbrajs, P. Clotten, P. J. Siemens, P. Navratil, R. A. Arndt, R. A. Arndt, R. A. Arndt, R. B. Wiringa, R. Blankenbecler, R. G. E. Timmermans, R. G. E. Timmermans, R. G. E. Timmermans, R. H. Landau, R. Machleidt, R. Machleidt, R. Machleidt, R. Machleidt, R. Machleidt, R. Machleidt, R. Machleidt, R. Machleidt, R. Woloshyn, S. A. Coon, S. Benck, S. Klarsfeld, S. W. Wissink, T. E. O. Ericson, T. Goldman, T. L. Houk, U. van Kolck, V. G. J. Stoks, V. G. J. Stoks, V. Stoks, V. Stoks, W. Buerkle, W. Dilg, W. Grein, W. Haeberli, W. Kretschmer, W. S. Wilburn   +110 more
core   +1 more source

All Nanozyme‐Based Cascade Reactions for Biomedical Applications: from Self‐Cascading Nanozyme to Immobilized Cascade Nanozyme

Advanced Science, Volume 13, Issue 6, 30 January 2026.
This review introduces the development and classification of all‐nanozyme cascade reaction systems, highlighting mechanistic insights and research methods for understanding catalytic features and design principles. It provides detailed classifications, surveys recent applications in biosensing and therapy, and discusses the challenges that all‐nanozyme
Caixia Zhu, Congcong Jiang, Hian Kee Lee, Yuanjian Zhang, Sheng Tang   +4 more
wiley   +1 more source

The method for approximate continuous Skyline query based on privacy protection in road network

Journal of Big Data
Existing road network continuous Skyline queries often neglect user location privacy and data privacy protection. This paper proposes a method for Approximate Continuous Skyline Query with Privacy Protection in road network (ACPP) environments to address
Song Li, Xiaolong Yang, Liping Zhang, Guanglu Sun   +3 more
doaj   +1 more source

An optimized chiral nucleon-nucleon interaction at next-to-next-to-leading order [PDF]

, 2013
We optimize the nucleon-nucleon interaction from chiral effective field theory at next-to-next- to-leading order. The resulting new chiral force NNLOopt yields \chi^2 \approx 1 per degree of freedom for laboratory energies below approximately 125 MeV. In
Baardsen, G., Ekström, A., Forssén, C., Hagen, G., Hjorth-Jensen, M., Jansen, G. R., Machleidt, R., Nazarewicz, W., Papenbrock, T., Sarich, J., Wild, S. M.   +10 more
core   +2 more sources

Crystal structure of fatty acid thioesterase A bound by 129 fragments provides diverse development opportunities

Pest Management Science, Volume 82, Issue 1, Page 151-168, January 2026.
Crystallographic fragment screening of A. thaliana FatA yielded 141 hits and along with orthogonal assays, this enables the target for rapid development of novel chemical matter to the currently available herbicides. Abstract BACKGROUND In order to alleviate the growing issue of herbicide resistance, diversification of the herbicide portfolio is ...
Ekaterina Kot, Matteo Paolo Ferla, Patricia Helen Hollinshead, Charles William Ernest Tomlinson, Daren Fearon, Jasmin Cara Aschenbrenner, Lizbé Koekemoer, Max Winokan, Michael Fairhead, Xiaomin Ni, Rod Chalk, Katherine Sara England, Laura Ortega Varga, Mark Greer Montgomery, Nicholas Phillip Mulholland, Frank von Delft   +15 more
wiley   +1 more source

Emerging Biomedical Engineering Therapies for Infected Diabetic Foot Ulcers: Toward Antibacterial Functionalization and Pathology‐Responsive Regulation

Small Science, Volume 6, Issue 1, January 2026.
Infected diabetic foot ulcer endangers patients with high amputation, disability, mortality risks, and heavy medical burdens. This review analyzes its pathogenic factors, the limitations of current treatments, the breakthroughs of responsive antimicrobial biomaterials, and the challenge of multifunctional biomaterial innovations for further developing ...
Yaqi Yao, Mengyi Huang, Yuetong Li, Yiqi Lin, Junjie Dong, Jianhang Du, Aixia Zhai, Changlong Bi, Luoyuan Li   +8 more
wiley   +1 more source