Results 201 to 210 of about 412 (248)

Physiologically based pharmacokinetic modeling and simulation of topiramate in populations with renal and hepatic impairment and considerations for drug–drug interactions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 510-522, March 2025.
Abstract Topiramate (TPM) is a broad‐spectrum antiepileptic drug (AED) commonly prescribed for approved and off‐label uses. Routine monitoring is suggested for clinical usage of TPM in special population due to its broad side effect profile. Therefore, it is crucial to further explore its pharmacokinetic characteristics.
Shuqing Chen, Chaozhuang Shen, Yuchen Tian, Yuhe Peng, Jing Hu, Haitang Xie, Ping Yin   +6 more
wiley   +1 more source

Et tu Brute? The Roles of Subordinate-Supervisor Similarities on the Relationship between Abusive Supervision and Employee Silence Behavior: A Study from the Subordinates' Perspectives. [PDF]

Behav Sci (Basel)
Bayhan Karapinar P, Tayfur Ekmekci O, Metin Camgoz S, López Bohle S, Miski Aydin E.   +4 more
europepmc   +1 more source

Deep Reinforcement Learning Based Autonomous Decision‐Making for Cooperative Uncrewed Aerial Vehicles: A Search and Rescue Real World Application

Journal of Field Robotics, EarlyView.
ABSTRACT This paper presents the first end‐to‐end framework that combines guidance, navigation, and centralized task allocation for multiple UAVs performing autonomous search‐and‐rescue (SAR) in GNSS‐denied indoor environments. A twin delayed deep deterministic policy gradient controller is trained with an artificial potential field (APF) reward that ...
Thomas Hickling, Maxwell Hogan, Abdulla Tammam, Nabil Aouf   +3 more
wiley   +1 more source

Silence is consent : Acquiescence and Estoppel in International Law

, 2018
openaire   +1 more source

A Methodological Pathway for Supporting the Transition From Theory to Practice in Action‐Oriented Research for Transformative Change

Sustainable Development, EarlyView.
ABSTRACT Over recent decades, action‐oriented research has gained prominence in co‐producing actionable knowledge to drive transformative change toward sustainability. However, further methodological developments are needed to support the transition to the application phase of such knowledge.
María D. López‐Rodríguez, Amanda Jiménez‐Aceituno, Enrica Garau, Cristina Quintas‐Soriano, Juan Miguel Requena‐Mullor, Lena Rölfer, María Mancilla García, Antonio J. Castro   +7 more
wiley   +1 more source

Urban Housing Markets and Sustainability Risk: Empirical Evidence From South African Cities

Sustainable Development, EarlyView.
ABSTRACT Despite the global shift toward sustainability and rising expectations for socially and environmentally responsible housing, evidence from South Africa's urban markets remains limited and underexplored. This study examines how sustainability‐related vulnerabilities shape downside housing risk across 60 cities between 2002 and 2021.
Bereket A. Ataro, Beatrice D. Simo‐Kengne, Rexford K. Asiama   +2 more
wiley   +1 more source

Peace and Inclusive Governance in Sustainable Development: Strengthening Institutions and Environmental Services

Sustainable Development, EarlyView.
ABSTRACT Sustainable Development Goal 16 (SDG 16) emphasizes peace, justice, and strong institutions as essential foundations for sustainable development. This study adopts a desktop‐based qualitative research approach to examine how institutional quality and governance systems influence progress toward SDG 16 and broader development outcomes.
Maryem Souiai, Hind Alkhowar, Haya Al‐Obaidli, Moza Al‐Muhannadi, Noora Alkhelaifi, Maythaa Al‐Kubaisi, Najlaa Al‐Khayareen, Shooq Al‐Sahoti, John N. Hahladakis   +8 more
wiley   +1 more source

Emergent Innovation in Systemic Programme Design: Retrospective Reflections on the Development of a Student‐Centred Masters in Systems Thinking

Systems Research and Behavioral Science, EarlyView.
ABSTRACT Our theory of education, based on a systemic understanding of the subjective and intersubjective construction of knowledge, is that students are motivated to study what is most meaningful to them. Meaningfulness is grounded in the students' prior experiences, which are highly diverse.
Wendy J. Gregory, Gerald Midgley
wiley   +1 more source

A Novel Approach to Energy Management in Electric Steelworks

steel research international, EarlyView.
Feed‐forward neural networks are exploited to estimate electric energy consumptions of the electric arc furnace and ladle furnace processes. The models are used to optimize production schedule so that more energy intensive grades are produced when the cost of energy is lower.
Valentina Colla, Stefano Dettori, Silvia Cateni, Marco Vannucci, Antonella Vignali, Claudio Mocci, Irene Dovichi, Davide Chionna, Lorenzo Vannini, Enrico Paluzzano, Costanzo Pietrosanti, Davide Onesti, Daniele Venier   +12 more
wiley   +1 more source

Contrastive Self‐Categorization as a Resource for Defending Cultural Stereotypes

Symbolic Interaction, EarlyView.
This study explores how speakers defend morally sanctionable cultural stereotypes from challenges in adult second language classrooms. Within the conversation analysis and membership categorization analysis frameworks, I examine two extended video‐recorded class discussions in which students maintain face‐threatening, stereotypical portrayals of ...
Nadja Tadic
wiley   +1 more source