Results 181 to 190 of about 129,997 (236)

How can children and young people have a voice in urban treescapes?

open access: yesPeople and Nature, EarlyView.
Abstract Scientific understanding of climate change has, to date, failed to result in sufficient action. This paper proposes that a deficit model of top‐down learning and dissemination in relation to public engagement with science may be part of the problem, particularly when considering the attitudes, values and empowerment of children and young ...
Simon Carr   +10 more
wiley   +1 more source

Digital surveillance of animals and nature recovery

open access: yesPeople and Nature, EarlyView.
Abstract Digital surveillance technologies (DSTs) are widely applied in nature recovery for their potential to generate novel data on species and ecosystems through digital tracking, automation (e.g. from hazardous locations) and from newly recruited citizen scientists.
William M. Adams
wiley   +1 more source

Physiologically based pharmacokinetic modeling and simulation of topiramate in populations with renal and hepatic impairment and considerations for drug–drug interactions

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 510-522, March 2025.
Abstract Topiramate (TPM) is a broad‐spectrum antiepileptic drug (AED) commonly prescribed for approved and off‐label uses. Routine monitoring is suggested for clinical usage of TPM in special population due to its broad side effect profile. Therefore, it is crucial to further explore its pharmacokinetic characteristics.
Shuqing Chen   +6 more
wiley   +1 more source

Baicalin Induces Ferroptosis in Breast Cancer Through a Novel STAT3/HO‐1/GPX4 Regulatory Axis

open access: yesPhytotherapy Research, EarlyView.
BA inhibits STAT3 phosphorylation and activation in BC cells, accompanied by decreased expression of HO‐1 and GPX4. Reduced GPX4 activity impairs lipid peroxide clearance, promoting ROS accumulation and lipid peroxidation, which ultimately triggers ferroptosis and inhibits cell proliferation.
Tingting Guo   +11 more
wiley   +1 more source

Analysis of flood events in the Three Gorges Reservoir Region using the coupled VIC‐CaMaFlood hydrological model

open access: yesRiver, EarlyView.
Abstract In recent years, the Three Gorges Reservoir Region (TGRR) has been increasingly affected by climate change, with frequent flood events posing challenges to regional flood control. The NO.1 flood of the Daning River in 2024 further highlights the severity of flood risks in the region.
Wenlong Song   +8 more
wiley   +1 more source

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