Results 221 to 230 of about 4,548,181 (253)
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Acquired resistance to drugs: the loss of selectivity

1975
A drug designer may build the highest degree of selectivity into his agents, only to see it lost through the development of resistance in his target organism. Drug resistance can arise in at least five distinct ways.
openaire   +1 more source

Biofilm-Associated Multi-Drug Resistance in Hospital-Acquired Infections: A Review

Infection and Drug Resistance, 2022
Azanaw Amare, Muluneh Assefa
exaly  

Somatic Evolution of Acquired Drug Resistance in Cancer

2011
Acquired drug resistance is a central problem in cancer medicine. The diverse molecular mechanisms of acquired drug resistance all arise through the same process of somatic (within-body) cellular evolution. Even targeted drugs are subject to this failure.
openaire   +1 more source

Multidrug Resistant Tuberculosis With Simultaneously Acquired Drug Resistance to Bedaquiline and Delamanid.

Clinical Infectious Diseases, 2021
Ken Ohta   +2 more
exaly  

Acquired drug resistance in tuberculosis in Harayana, India.

The Journal of the Association of Physicians of India, 2001
Sputa of 200 treatment failure cases of pulmonary tuberculosis over a period of 1991-1995 were subjected to culture and sensitivity testing against commonly used anti-tuberculosis drugs. Out of 200 cases, 75% revealed resistance to one or more anti-TB drugs, resistance to isoniazid was observed in 72% cases, it was 49% for rifampicin, and 37% for ...
A K, Janmeja, B, Raj
openaire   +1 more source

SITES OF ACTION OF AMETHOPTERIN: INTRINSIC AND ACQUIRED DRUG RESISTANCE*

Annals of the New York Academy of Sciences, 1971
K R, Harrap   +3 more
openaire   +2 more sources

Elevated Expression of LGR5 and WNT Signaling Factors in Neuroblastoma Cells With Acquired Drug Resistance

Cancer Investigation, 2023
Jane Carr-Wilkinson   +2 more
exaly  

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