Results 1 to 10 of about 84,855 (97)

HIV Pretreatment Drug Resistance Trends in Mexico City, 2017–2020 [PDF]

Pathogens, 2021
In response to increasing pretreatment drug resistance (PDR), Mexico changed its national antiretroviral treatment (ART) policy, recommending and procuring second-generation integrase strand-transfer inhibitor (INSTI)-based regimens as preferred first ...
Claudia García-Morales, Daniela Tapia-Trejo, Margarita Matías-Florentino, Verónica Sonia Quiroz-Morales, Vanessa Dávila-Conn, Ángeles Beristain-Barreda, Miroslava Cárdenas-Sandoval, Manuel Becerril-Rodríguez, Patricia Iracheta-Hernández, Israel Macías-González, Rebecca García-Mendiola, Alejandro Guzmán-Carmona, Eduardo Zarza-Sánchez, Raúl Adrián Cruz, Andrea González-Rodríguez, Gustavo Reyes-Terán, Santiago Ávila-Ríos   +16 more
doaj   +4 more sources

Prevalence and transmission of pretreatment drug resistance in people living with HIV-1 in Shanghai China, 2017–2021 [PDF]

Virulence
The implementation of pretreatment drug-resistance (PDR) surveillance among people living with HIV-1 (PLWH) is a top priority in countries using efavirenz (EFV)/nevirapine (NVP) for first-line ART.
Min Zhang, Yingying Ma, Zhenyan Wang, Gang Wang, Qianying Wang, Xin Li, Feng Lin, Chiyu Zhang   +7 more
doaj   +4 more sources

Molecular epidemiology and pretreatment drug resistance of HIV-1 among newly diagnosed individuals in Nanning City, Guangxi, China [PDF]

Microbiology Spectrum
Emerging pretreatment drug resistance (PDR) significantly reduces the effectiveness of HIV antiretroviral therapy (ART). This study assessed the prevalence, associated factors, and transmission networks of PDR among newly diagnosed, ART-naïve individuals
Ting Huang, Jinfeng He, Qiuqian Su, Liangjia Wei, Jiao Qin, Xinju Huang, Chunxing Tao, Fei Zhang, Li Ye, Ping Cen, Hao Liang, Bingyu Liang   +11 more
doaj   +4 more sources

HIV-1 pretreatment drug resistance and genetic transmission network in the southwest border region of China [PDF]

BMC Infectious Diseases, 2022
Background HIV drug resistance increased with the widespread use of antiretroviral drugs, and posed great threat to antiretroviral therapy (ART). Pu’er Prefecture, lying in the southwest of Yunnan Province, China, borders Myanmar, Laos and Vietnam, is ...
Difei Li, Huichao Chen, Huilan Li, Yanling Ma, Lijuan Dong, Jie Dai, Xiaomei Jin, Min Yang, Zhijun Zeng, Pengyan Sun, Zhizhong Song, Min Chen   +11 more
doaj   +2 more sources

Molecular transmission network of pretreatment drug resistance among human immunodeficiency virus-positive individuals and the impact of virological failure on those who received antiretroviral therapy in China [PDF]

Frontiers in Medicine, 2022
ObjectivesWe investigated the prevalence of pretreatment drug resistance (PDR), the molecular transmission network among HIV-positive individuals, and the impact of virological failure on those who received antiretroviral therapy (ART) in China ...
Hongli Chen, Jing Hu, Chang Song, Miaomiao Li, Yesheng Zhou, Aobo Dong, Ruihua Kang, Jingjing Hao, Jiaxin Zhang, Xiu Liu, Dan Li, Yi Feng, Lingjie Liao, Yuhua Ruan, Hui Xing, Yiming Shao   +15 more
doaj   +2 more sources

The association between HIV pretreatment drug resistance and virological outcomes in children and adults in sub-Saharan Africa: A systematic review and meta-analysis. [PDF]

PLoS ONE
IntroductionPretreatment drug resistance (PDR) could occur in antiretroviral treatment (ART) naïve individuals, those previously exposed to ART, or individuals re-initiating ARV after a long period of interruption.
Ebako Ndip Takem, Christopher Coox, Judith Shang, Clement Ndongmo, Emily Kainne Dokubo   +4 more
doaj   +2 more sources

Addressing Pediatric HIV Pretreatment Drug Resistance and Virologic Failure in Sub-Saharan Africa: A Cost-Effectiveness Analysis of Diagnostic-Based Strategies in Children ≥3 Years Old [PDF]

Diagnostics, 2021
Improvement of antiretroviral therapy (ART) regimen switching practices and implementation of pretreatment drug resistance (PDR) testing are two potential approaches to improve health outcomes for children living with HIV.
Mutita Siriruchatanon, Shan Liu, James G. Carlucci, Eva A. Enns, Horacio A. Duarte   +4 more
doaj   +2 more sources

Prevalence of HIV-1 pretreatment drug resistance among treatment naïve pregnant women in Bissau, Guinea Bissau. [PDF]

PLoS ONE, 2018
BACKGROUND:With increased access to antiretroviral treatment (ART) in sub-Saharan Africa emergence of HIV-1 pretreatment drug resistance constitutes a serious risk.
Sten Wilhelmson, Fredrik Månsson, Jacob Lopatko Lindman, Ansu Biai, Joakim Esbjörnsson, Hans Norrgren, Marianne Jansson, Patrik Medstrand, SWEGUB CORE group   +8 more
doaj   +2 more sources

Molecular Transmission Network and Pretreatment Drug Resistance of Newly Diagnosed HIV-1 Infections in Taizhou, a Coastal City in Eastern China, from 2021–2023 [PDF]

Pathogens
Objective: This study conducted a comprehensive analysis of molecular transmission networks and pretreatment drug resistance (PDR) in newly diagnosed HIV-1 infections in Taizhou, China.
Junxiao Lin, Haijiang Lin, Guixia Li, Shanling Wang, Tingting Wang, Qiguo Meng, Tingting Hua, Yali Xie, Jiafeng Zhang, Weiwei Shen   +9 more
doaj   +2 more sources

Using Molecular Transmission Networks to Reveal the Epidemic of Pretreatment HIV-1 Drug Resistance in Guangxi, China

Frontiers in Genetics, 2021
IntroductionPretreatment drug resistance (PDR) is becoming an obstacle to the success of ART. This study investigated the prevalence of PDR and the transmission clusters (TCs) of drug resistance mutations (DRMs) in two cities where drug abuse used to be ...
Fei Zhang, Bingyu Liang, Bingyu Liang, Xu Liang, Zhaosen Lin, Yuan Yang, Na Liang, Yao Yang, Huayue Liang, Jiaxiao Jiang, Jiegang Huang, Rongye Huang, Shanmei Zhong, Cai Qin, Junjun Jiang, Junjun Jiang, Li Ye, Li Ye, Hao Liang, Hao Liang   +19 more
doaj   +3 more sources