Results 11 to 20 of about 3,987,151 (271)

Pretreatment HIV‐1 Drug Resistance Among Newly Diagnosed People in Eastern Ethiopia

Health Science Reports
Background and Aims In Ethiopia, HIV‐1 pretreatment drug resistance (PDR) data are limited owing to a lack of routine genotyping resistance tests. This study aimed to determine the prevalence of HIV‐1 PDR mutations and genetic diversity among newly ...
Abdella Gemechu, Adane Mihret, Mesfin Mengesha, Dawit Hailu Alemayehu, Eleni Kidane, Abraham Aseffa, Rawleigh Howe, Berhanu Seyoum, Andargachew Mulu   +8 more
doaj   +4 more sources

Impact of HIV Pretreatment Drug Resistance on Secondary Transmission Through Treatment Dropout: A Prospective Population-Based Study in Southwestern China [PDF]

Infection and Drug Resistance
Yi Chen,1,* Xiaoshan Xu,2,* Huanhuan Chen,3,* Xiangjun Zhang,4 Qiuying Zhu,3 Shujia Liang,3 Hui Xing,2 Lingjie Liao,2 Yi Feng,2 Yiming Shao,2 Yuhua Ruan,2 Guanghua Lan,3 Jianjun Li3 1The Guangxi Academy of Medical Sciences, The ...
Chen Y, Xu X, Chen H, Zhang X, Zhu Q, Liang S, Xing H, Liao L, Feng Y, Shao Y, Ruan Y, Lan G, Li J   +12 more
doaj   +4 more sources

Pretreatment drug resistance in people living with HIV: A large retrospective cohort study in Chongqing, China. [PDF]

HIV Med, 2022
AbstractObjectivesThe emergence of pretreatment drug resistance (PDR) caused by increased usage of antiretroviral therapy (ART) represents a significant challenge to HIV management. In this study, we evaluated the prevalence of PDR in people living with HIV (PLWH) in Chongqing, China.MethodsWe retrospectively collected the data of 1110 ART‐naïve PLWH ...
Liu M, He XQ, Deng RN, Tang SQ, Harypursat V, Lu YQ, He K, Huo Q, Yang HH, Liu Q, Chen YK.   +10 more
europepmc   +4 more sources

HIV-1 genetic diversity and pretreatment drug resistance survey prior to dolutegravir introduction in Senegal. [PDF]

IJID Reg
This study aimed to document the prevalence of pretreatment drug resistance in antiretroviral therapy-naïve patients in Senegal, describe mutation profiles, and evaluate their potential impact on future therapy.A pretreatment drug resistance survey was carried out in 35 sites throughout the country between 2017 and 2018 using dried blood spots and ...
Fall M, Leye N, Vidal N, Niasse F, Tchiakpe E, Diakhaby B, Thiam MS, Diouara AAM, Niama FR, Thiam S, Toure-Kane C, Diop-Ndiaye H.   +11 more
europepmc   +4 more sources

Pretreatment HIV drug resistance in adults initiating antiretroviral therapy in China, 2017 [PDF]

Infectious Diseases of Poverty, 2020
Background After the scale-up of antiretroviral therapy (ART) for HIV infected people, increasing numbers of patients have pretreatment drug resistance (PDR).
Rui-Hua Kang, Shu-Jia Liang, Yan-Ling Ma, Shu Liang, Lin Xiao, Xin-Hui Zhang, Hong-Yan Lu, Xiao-Qin Xu, Shui-Bin Luo, Xiao-Guang Sun, Lin Chen, Jian-Mei He, Guo-Hui Wu, Ling-Jie Liao, Hui Xing, Yi-Ming Shao, Yu-Hua Ruan   +16 more
doaj   +3 more sources

Diversity of HIV-1 genotypes and high prevalence of pretreatment drug resistance in newly diagnosed HIV-infected patients in Shanghai, China [PDF]

BMC Infectious Diseases, 2019
Background Genetic variability and liability to develop drug-resistant mutations are the main characteristics of HIV-1, which can not only increase the risk of antiretroviral treatment (ART) failure, but also can lead to the spread of resistant strains ...
Zhenyan Wang, Min Zhang, Renfang Zhang, Li Liu, Yinzhong Shen, Jiangrong Wang, Hongzhou Lu   +6 more
doaj   +2 more sources

A Sensitivity and Consistency Comparison Between Next-Generation Sequencing and Sanger Sequencing in HIV-1 Pretreatment Drug Resistance Testing [PDF]

Viruses
Next-generation sequencing (NGS) for HIV drug resistance (DR) testing has an increasing number of applications for the detection of low-abundance drug-resistant variants (LA-DRVs) in regard to its features as a quasi-species.
Ying Zhou, Fei Ouyang, Xiaoyan Liu, Jing Lu, Haiyang Hu, Qi Sun, Haitao Yang   +6 more
doaj   +2 more sources

Cost-effectiveness of pretreatment HIV drug resistance testing in people living with HIV in Iran.

PLoS ONE
IntroductionHIV drug resistance (HIVDR) is an important challenge in the fight against HIV/AIDS and can threaten progress toward achieving the target of HIV elimination by 2030. Genotyping pretreatment HIVDR testing (DRT) has been proposed as a potential
Hossein Mirzaei, Abedin Iranpour, Firooz Esmaeilzadeh, Mohsen Barouni, Fatemeh Mehrabi, Ebrahim Ranjbar, Hamid Sharifi   +6 more
doaj   +3 more sources

Disparity of HIV-1 Pretreatment Drug Resistance in Men Who Have Sex With Men and the Heterosexual Population in Guangxi, China. [PDF]

Open Forum Infect Dis, 2023
Pang X, Liang S, Tang K, Huang J, He Q, Fang N, Xie B, Xie X, Wang H, Hu Y, Lan G.   +10 more
europepmc   +2 more sources

Characterization of sexually acquired HIV-1 transmission networks and genetic variation in northern frontier China, 2021–2024 [PDF]

Frontiers in Public Health
BackgroundIn Baotou, sexual transmission is the primary route of HIV-1 infection among newly reported cases. Given the increasing prevalence in recent years, this study aimed to identify the factors driving local viral spread and analyze the ...
Yu Liu, Yu Liu, Yu Liu, Hanping Li, Baobao Bai, Yao Li, Ziwei Liu, Xiaodong Liu, Juan Du, Yongjian Liu, Lei Jia, Jingwan Han, Bohan Zhang, Jingyun Li, Lin Li, Hong Yang, Hong Yang   +16 more
doaj   +2 more sources