Results 21 to 30 of about 2,391 (154)

Emerging Topical and Systemic JAK Inhibitors in Dermatology [PDF]

, 2019
Accumulating data on cellular and molecular pathways help to develop novel therapeutic strategies in skin inflammation and autoimmunity. Examples are psoriasis and atopic dermatitis, two clinically and immunologically well-defined disorders.
Ghoreschi, Kamran, Meier, Katharina, Solimani, Farzan   +2 more
core   +1 more source

A preliminary overview of skin and skeletal diseases and traumata in small cetaceans from South American waters [PDF]

, 2007
We succinctly review and document new cases of diseases of the skin and the skeletal system and external traumata in cetaceans from Ecuador, Colombia, Peru, Chile, Argentina, Uruguay, Brazil, and Venezuela.
Avila, I.C., Bolaños-Jimenez, J., Castineira, E., Crespo, E., Di Beneditto, A.P., Echegaray, M., Flach, L., Flores, P.A.C., Fragoso, A.B., Félix, F., Haase, B., Herrera, J.C., Laeta, M., Mendonça de Souza, S.M.F., Montes, D., Moreno, I.B., Ott, P.H., Reyes, J.C., Sanino, G.P., Siciliano, S., Tobón, I.C., Van Bressem, M.-F., Van Waerebeek, K., Viddi, F.   +23 more
core   +1 more source

The ABCC6 Transporter: A New Player in Biomineralization [PDF]

, 2017
Pseudoxanthoma elasticum (PXE) is an inherited metabolic disease with autosomal recessive inheritance caused by mutations in the ABCC6 gene. Since the first description of the disease in 1896, alleging a disease involving the elastic fibers, the concept ...
Arányi, Tamás, Favre, Guillaume, Fülöp, Krisztina, Laurain, Audrey, Szeri, Flóra   +4 more
core   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Transporters

British Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Laura Amarosi, Catriona M. H. Anderson, Philip M. Beart, Stefan Broer, Paul A. Dawson, Gergely Gyimesi, Bruno Hagenbuch, James R. Hammond, Jules C. Hancox, Michal Hershfinkel, Ken‐ichi Inui, Yoshikatsu Kanai, Stephan Kemp, Edmund R. S. Kunji, Gavin Stewart, Sotiria Tavoulari, David T. Thwaites, Tiziano Verri   +28 more
wiley   +1 more source

Diagnosis and management of pseudohypoparathyroidism and related disorders: first international Consensus Statement [PDF]

, 2018
This Consensus Statement covers recommendations for the diagnosis and management of patients with pseudohypoparathyroidism (PHP) and related disorders, which comprise metabolic disorders characterized by physical findings that variably include short ...
Ahmed, S.F. (Sayed), Bastepe, M. (Murat), Bufo, R. (Roberto), Choplin, T. (Timothée), de Filippo, G. (Gianpaolo), de Sanctis, L. (Luisa), Devernois, G. (Guillemette), Eggermann, T. (Thomas), Elli, F.M. (Francesca M.), Freson, K. (Kathleen), García Ramirez, A. (Aurora), Germain-Lee, E.L. (Emily L.), Groussin, L. (Lionel), Hamdy, N.A. (Neveen), Hanna, P. (Patrick), Hiort, O. (Olaf), Jüppner, H. (Harald), Kamenický, P. (Peter), Knight, N. (Nina), Kottler, M.-L. (Marie-Laure), Le Norcy, E. (Elvire), Lecumberri, B. (Beatriz), Levine, M.A. (Michael A.), Linglart, A. (Agnès), Mantovani, G. (Giovanna), Martin, R. (Regina), Martos-Moreno, G.Á. (Gabriel Ángel), Minagawa, M. (Masanori), Monk, A.B. (Alastair), Murray, P. (Philip), Mäkitie, O. (Outi), Pereda, A. (Arrate), Perez de Nanclares, G. (Guiomar), Pignolo, R. (Robert), Rejnmark, L. (Lars), Rodado, R. (Rebecca), Rothenbuhler, A. (Anya), Saraff, V. (Vrinda), Shoemaker, A.H. (Ashley H.), Shore, E.M. (Eileen M.), Silve, C. (Caroline), Thiele, S. (Susanne), Turan, S. (Serap), Usardi, A. (Alessia), Woods, P. (Philip), Zillikens, M.C. (Carola)   +45 more
core   +2 more sources

Imaging of skull vault tumors in adults [PDF]

, 2020
The skull vault, formed by the flat bones of the skull, has a limited spectrum of disease that lies between the fields of neuro- and musculoskeletal radiology.
Aguilera, Carles, Cos, Mònica, Hernández Gañán, Javier, Majós Torró, Carlos, Mora, Paloma, Narváez, José A., Naval Baudin, Pablo, Pons Escoda, Albert   +7 more
core   +1 more source

Hierarchical Superposition Framework Reveals the Complex Effects of Natural Medicine Formulas

Advanced Intelligent Systems, Volume 7, Issue 11, November 2025.
A novel hierarchical superposition pharmacological model incorporates the principle of hierarchical structures from physics to simulate the spatiotemporal dynamics of drug combinations, to elucidate the universal law underlying drug combination effects. By modeling cross‐level causal transmission and attenuation, it advances beyond traditional additive
Weifeng Liang, Dingsi Xiang, Shengli Mi, Jiajun Huang   +3 more
wiley   +1 more source

Seronegative spondyloarthropathies : a review : part I: classification and differential diagnosis [PDF]

, 1993
The seronegative spondyloarthropathies comprise a group of non-rheumatoid disorders with similar clinical, laboratory and genetic features. Recognition of new clinical features has supported the notion that they all form part of a clinical spectrum ...
Borg, Andrew A., Dawes, Peter T., Hothersall, T.E.   +2 more
core  

Conditional Deletion of Murine Fgf23: Interruption of the Normal Skeletal Responses to Phosphate Challenge and Rescue of Genetic Hypophosphatemia [PDF]

, 2016
The transgenic and knockout (KO) animals involving Fgf23 have been highly informative in defining novel aspects of mineral metabolism, but are limited by shortened lifespan, inability of spatial/temporal FGF23 control, and infertility of the global KO ...
Allen, Matthew R., Bellido, Teresita, Cass, Taryn A., Clinkenbeard, Erica L., Hum, Julia M., Ni, Pu, White, Kenneth E.   +6 more
core   +1 more source

The Benefit of Menopausal Hormone Therapy on Bone Density and Microarchitecture Persists After its Withdrawal. [PDF]

, 2016
Menopausal hormone therapy (MHT) favorably affects bone mineral density (BMD). Whether MHT also affects bone microarchitecture, as assessed by trabecular bone score (TBS), has never been evaluated. Our objective was to assess the effect of MHT on TBS and
Gonzalez-Rodriguez, E., Hans, D., Lamy, O., Marques-Vidal, P.M., Papadakis, G., Vollenweider, P., Waeber, G.   +6 more
core   +1 more source