Results 31 to 40 of about 6,381 (216)
Abundance of TipR and AcrA in various tipR and PacrA point mutants. [PDF]
Immunoblots probed with polyclonal antibodies to AcrA and to TipR in extracts of different PacrA (B, C, and D) or tipR (A) mutants. All inductions (+) were performed after 2 hours of treatment with 10 μg/mL of Nal on exponentially grown cells in PYE ...
Bastien Casu (3935507) +6 more
core +1 more source
Probing the Assembly, Functional Relevance, and Dynamics of AcrA in Multi Drug Efflux in \u3ci\u3eEscherichia coli\u3c/i\u3e [PDF]
Efflux pumps and low permeability of the outer membrane of gram-negative bacteria are major culprits in drug resistance. The most studied of these multidrug efflux pumps is the AcrAB-TolC, a complex of three proteins, the inner membrane transporter AcrB,
Ojo, Isoiza
core +2 more sources
A total of 87 clinical specimens from midstream urine samples were collected from children with urinary tract infection, all specimens were inoculated on suitable media for isolation and primary identification of bacteria then biochemical tests were ...
Wedad Adil Kadhim +1 more
doaj +1 more source
Levels of a labile AcrA variant, AcrAL222Q, in cells with various genetic backgrounds. [PDF]
Cultures were grown at 30°C and 37°C and AcrAL222Q levels were determined from whole cell extracts by Western blot analysis. BamA, detected by BamA antibodies, was used as a gel loading control.
Henri Gerken (177650) +3 more
core +1 more source
AcrB-AcrA Fusion Proteins That Act as Multidrug Efflux Transporters [PDF]
ABSTRACT The AcrAB-TolC system in Escherichia coli is an intrinsic RND-type multidrug efflux transporter that functions as a tripartite complex of the inner membrane transporter AcrB, the outer membrane channel TolC, and the adaptor protein AcrA.
Katsuhiko Hayashi +6 more
openaire +2 more sources
Background Aboriginal and Torres Strait Islander youth are vulnerable to racism, trauma and Lateral Violence (LV) where negative feelings and behaviours are directed towards members within their own oppressed group.
Yvonne Clark +7 more
doaj +1 more source
Brucellosis is a highly contagious zoonosis and still a major human health problem in endemic areas of the world. Although several diagnostic tools are available, most of them are difficult to implement especially in developing countries where complex ...
Andrés E Ciocchini +8 more
doaj +1 more source
Interdomain Flexibility and pH-Induced Conformational Changes of AcrA Revealed by Molecular Dynamics Simulations [PDF]
The membrane fusion protein (MFP) AcrA is proposed to link the inner membrane transporter AcrB and outer membrane protein TolC, forming the tripartite AcrAB–TolC efflux pump, and was shown to be functionally indispensible.
Kangnian Fan (187757) +3 more
core +1 more source
Functional relevance of AcrB Trimerization in pump assembly and substrate binding.
AcrB is a multidrug transporter in the inner membrane of Escherichia coli. It is an obligate homotrimer and forms a tripartite efflux complex with AcrA and TolC. AcrB is the engine of the efflux machinery and determines substrate specificity.
Wei Lu +5 more
doaj +1 more source
A Teoria dos Conjuntos de Cantor
No final dos anos 50 e começo doe anos 60, houve uma reformulação significativa da Matemática no Brasil. Sob a bandeira do modernismo, seus defensores buscaram inovações no ensino da Matemática.
Antônio Acra Freiria
doaj +1 more source

