Results 21 to 30 of about 166,677 (165)

Adjuvant Anti-PD-1 Antibody Therapy for Advanced Melanoma: A Multicentre Study of 78 Japanese Cases

Acta Dermato-Venereologica, 2022
Anti-PD-1 antibodies (Abs) are among the optimal adjuvant therapies for melanoma at high risk of recurrence, especially BRAF wild-type melanoma, but the anti-tumour effects of anti-PD-1 Abs in the adjuvant setting for acral melanoma have not been ...
Yusuke Muto, Yumi Kambayashi, Hiroshi Kato, Satoshi Fukushima, Takamichi Ito, Takeo Maekawa, Yasuhiro Fujisawa, Koji Yoshino, Hiroshi Uchi, Shigeto Matsushita, Yuki Yamamoto, Ryo Amagai, Kentaro Ohuchi, Akira Hashimoto, Taku Fujimura   +14 more
doaj   +1 more source

A single-cell analysis reveals tumor heterogeneity and immune environment of acral melanoma

Nature Communications, 2022
Studying the cell composition of acral melanoma at the single-cell level could provide some clues about its poor response to immunotherapy. Here, the authors analyse acral and cutaneous melanoma patient samples using single-cell RNA-sequencing, and ...
Chao Zhang, Hongru Shen, Tielong Yang, Ting Li, Xinyue Liu, Jin Wang, Zhichao Liao, Junqiang Wei, Jia Lu, Haotian Liu, Lijie Xiang, Yichen Yang, Meng Yang, Duan Wang, Yang Li, Ruwei Xing, Sheng Teng, Jun Zhao, Yun Yang, Gang Zhao, Kexin Chen, Xiangchun Li, Jilong Yang   +22 more
doaj   +1 more source

Development of a practical guide for the early recognition for malignant melanoma of the foot and nail unit [PDF]

, 2010
Background: malignant melanoma is a rare but potentially lethal form of cancer which may arise on the foot. Evidence suggests that due to misdiagnosis and later recognition, foot melanoma has a poorer prognosis than cutaneous melanoma elsewhere.Methods ...
David AR de Berker, de Berker, David, Ivan R Bristow, de Berker David AR, Bristow, Ivan R., Bristow Ivan R   +5 more
core   +2 more sources

Time-varying pattern of recurrence risk for localized melanoma in China

World Journal of Surgical Oncology, 2020
Background Acral and mucosal melanomas are rarely seen in Caucasians but common in China. There are limited data on the recurrence characteristics for these patients.
Xizhi Wen, Dandan Li, Jingjing Zhao, Jingjing Li, Tao Yang, Ya Ding, Ruiqing Peng, Baoyan Zhu, Fuxue Huang, Xiaoshi Zhang   +9 more
doaj   +1 more source

Clinical guidelines for the recognition of melanoma of the foot and nail unit [PDF]

, 2010
Malignant melanoma is a life threatening skin tumour which may arise on the foot. The prognosis for the condition is good when lesions are diagnosed and treated early.
David AR de Berker, Bristow, I.R., de Berker, D.A.R., Turner Richard J, Bristow Ivan R, Katharine M Acland, Richard J Turner, Jonathan Bowling, Ivan R Bristow, Acland Katharine M, de Berker David AR, Bowling, J., Turner, R.J., Acland, K. M., Bowling Jonathan   +14 more
core   +2 more sources

Next-generation sequencing in advanced Chinese melanoma reveals therapeutic targets and prognostic biomarkers for immunotherapy

Scientific Reports, 2022
Limited studies have interrogated the genomic landscape of Chinese melanoma in which acral and mucosal melanoma are the mainstay. In this study, we carried out a retrospective analysis on 81 Chinese melanoma patients (15 acral, 25 mucosal and 41 ...
Fuxue Huang, Jingjing Li, Xizhi Wen, Baoyan Zhu, Wei Liu, Jiuhong Wang, Hang Jiang, Ya Ding, Dandan Li, Xiaoshi Zhang   +9 more
doaj   +1 more source

Cutaneous and acral melanoma cross-OMICs reveals prognostic cancer drivers associated with pathobiology and ultraviolet exposure

Nature Communications, 2022
While cutaneous melanoma is linked to UV radiation, acral melanoma is not. Epigenetic mechanisms function as sensors to exposures and determinants of cell identity.
Anna Luiza Silva Almeida Vicente, Alexei Novoloaca, Vincent Cahais, Zainab Awada, Cyrille Cuenin, Natália Spitz, André Lopes Carvalho, Adriane Feijó Evangelista, Camila Souza Crovador, Rui Manuel Reis, Zdenko Herceg, Vinicius de Lima Vazquez, Akram Ghantous   +12 more
doaj   +1 more source

4320 Acral, Head and Neck Melanoma Subtype Classification Performance Using A Convolutional Neural Network (CNN) Trained On a Public Dataset

Journal of Clinical and Translational Science, 2020
OBJECTIVES/GOALS: Composition of demographics or image types in publicly available datasets may detract from deep learning (DL) diagnosis performance of underrepresented melanoma subtypes. We evaluate a DL model’s performance on melanoma subtypes (acral;
Payal Shah, Sameer Arya, Lauren Rangel, Yindalon Aphinyanaphongs   +3 more
doaj   +1 more source

Differences in the Tumor Immunity-related Gene Expression Profile Between Acral lentiginous and Non-acral Melanoma

, 2023
Supplement table Ⅰ. Clinicopathological features of patients in our studySupplement table Ⅱ. Materials and methods of gene expression analysisSupplement table Ⅲ. Lists of differentially expressed genes in acral lentiginous melanoma compared to non-acral
Choi, M (via Mendeley Data)
core   +1 more source

Tasa de recurrencia e implicación del margen quirúrgico en la supervivencia del paciente con melanoma acral. ¿Es necesario un margen amplio?

Gaceta Médica de México, 2023
Introducción: La extensión apropiada de los márgenes de resección en el melanoma acral no está claramente establecida. Objetivo: Investigar si la escisión con margen estrecho es adecuada en el melanoma acral grueso.
Leonardo S. Lino-Silva, Raúl Hernández-Romero, Juan S. García-Herrera, César Zepeda-Najar, Rosa A. Salcedo-Hernández, Alberto M. León-Takahashi, Marín G. Escobar-Jiménez, Ángel Herrera-Gómez   +7 more
doaj   +1 more source