Results 51 to 60 of about 166,677 (165)

Acral Melanoma: A Patient’s Experience and Physician’s Commentary

Dermatology and Therapy, 2018
This article, co-authored by a patient diagnosed with acral melanoma, discusses the patient’s experience of being diagnosed with and treated with surgery for this disease.
Elizabeth Greenwald, Anonymous Patient, David Polsky, Tracey N. Liebman   +3 more
doaj   +1 more source

Efficacy of anti-PD-1 and ipilimumab alone or in combination in acral melanoma

Journal for ImmunoTherapy of Cancer, 2022
Background Acral melanoma is a rare melanoma subtype with poor prognosis. Importantly, these patients were not identified as a specific subgroup in the landmark melanoma trials involving ipilimumab and the anti-programmed cell death protein-1 (PD-1 ...
Bart Neyns, Lisa Zimmer, Caroline Robert, Celeste Lebbe, Olivier Michielin, Omid Hamid, Anne Zaremba, Oliver Klein, Ruth Plummer, Joanna Mangana, Paolo A Ascierto, Katharina C Kähler, Georgina V Long, Ryan Sullivan, Grant A McArthur, Michael Weichenthal, Egle Ramelyte, Meghan J Mooradian, Douglas B Johnson, Alexander Shoushtari, Christian U Blank, Judith M Versluis, Prachi Bhave, Claudia Trojanello, Lu Si, Inderjit Mehmi, Tasnia Ahmed, Alexander M Menzies, Adnan Khattak, Severine Roy, Matteo S Carlino, Paul C Lorigan, Clara Allayous, Rachel Roberts-Thomson, Florentia Dimitriou, Kathleen Batty, Thierry Lesimple, Serigne N Lo, Alexandre Wicky, Richard Heywood, Lena Tran, Anna Stansfeld, Julia K Schwarze, Andrea Maurichi, Hui-Ling Yeoh, Mario Santinami, Andrew M Haydon   +46 more
doaj   +1 more source

Eruptive Acral Melanocytic Lesions Associated With Capecitabine

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Eruptive nevi and lentigines have been reported to occur in the setting of immunosuppression, which may be medication‐induced. The associated histopathologic findings have not been well described in the literature. Herein, we report the case of a woman in her 60s who had been receiving chemotherapy treatment with capecitabine, a prodrug of 5 ...
Madison Smith, Annie Jin, Jonathan A. Miles, Rosalie Elenitsas, Danielle M. DeHoratius, Emily Y. Chu   +5 more
wiley   +1 more source

Pembrolizumab in Chinese patients with advanced melanoma: 3-year follow-up of the KEYNOTE-151 study

Frontiers in Immunology, 2022
Survival is generally poor for Chinese patients with advanced melanoma because of high rates of acral and mucosal melanoma and limited therapeutic options.
Lu Si, Xiaoshi Zhang, Yongqian Shu, Hongming Pan, Di Wu, Jiwei Liu, Lili Mao, Xuan Wang, Xizhi Wen, Yanhong Gu, Lingjun Zhu, Shijie Lan, Xin Cai, Scott J. Diede, Haiyan Dai, Cuizhen Niu, Jianfeng Li, Jun Guo   +17 more
doaj   +1 more source

Cytology‐First Diagnostic Workflow for Melanoma of Unknown Primary With Molecular Profiling

Cytopathology, EarlyView.
Cytology‑first diagnostic workflow for melanoma of unknown primary. Fine‑needle aspiration of an enlarged lymph node enables rapid cytologic evaluation and immunocytochemical confirmation of melanocytic lineage (SOX10). This early cytologic diagnosis facilitates timely surgical excision and comprehensive genomic profiling, supporting integrated ...
Hong Yu, Mokhtar Abdelhammed, Xu Cao, Nisha S. Ramani   +3 more
wiley   +1 more source

Region Adjacency Graph Approach for Acral Melanocytic Lesion Segmentation

Applied Sciences, 2018
Malignant melanoma is among the fastest increasing malignancies in many countries. Due to its propensity to metastasize and lack of effective therapies for most patients with advanced disease, early detection of melanoma is a clinical imperative.
Joanna Jaworek-Korjakowska, Pawel Kleczek   +1 more
doaj   +1 more source

Multiclass convolutional neural network vs. 96 dermatologists in skin lesion diagnosis, an international study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Artificial intelligence was shown to improve diagnostic accuracy for skin cancer detection. While most clinically approved models provide binary “benign/malignant” classifications, multiclass predictions may offer greater clinical utility.
Katharina Susanne Kommoss, Julia Katharina Winkler, Anastasia Sophie Vollmer, Christine Mueller‐Christmann, Ferdinand Toberer, Wilhelm Stolz, Teresa Kraenke, Rainer Hofmann‐Wellenhof, Andreas Blum, Alexander Enk, Albert Rosenberger, Holger Andreas Haenssle   +11 more
wiley   +1 more source

Age‐related dermatoscopic features of excised melanomas versus nevi in 832 high risk patients

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Melanocytic nevi show distinct age‐related dermoscopic patterns. However, data on age‐related patterns of melanomas are lacking. This study aimed to identify age‐related static and dynamic dermoscopic patterns of melanomas. Patients and methods Explorative cross‐sectional cohort study between October 1996 and May 2012,
Jana Burghaus‐Zhang, Julia Katharina Winkler, Katharina Susanne Kommoss, Anastasia Sophie Vollmer, Alexander Enk, Timo Buhl, Holger Andreas Haenssle   +6 more
wiley   +1 more source

Acral Melanoma: Epidemiology and Treatment Outcomes

, 2021
Acral melanomas are a subtype of melanoma which affect the palms, nails and soles of the feet. Acral melanomas are characterised by different mutation signatures, prognoses and treatment outcomes compared to other forms of melanoma.
Cho, Kenneth Kunhee
core  

AI‐assisted diagnosis of nail unit melanoma and melanonychia using a clinical deep learning model

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Nail unit melanoma (NUM) is a rare but potentially fatal malignancy often misdiagnosed as melanonychia. Because biopsy may cause permanent nail dystrophy, accurate noninvasive diagnosis is essential. This study aimed to develop and validate an artificial intelligence model to distinguish NUM from benign melanonychia ...
Yusung Chu, Sejung Yang, Jin‐Woong Jung, Jun Young Kim, Joon‐Goon Kim, Hae June Sung, Byungho Oh   +6 more
wiley   +1 more source