Results 101 to 110 of about 53,333 (203)

3,3-Dimethyl-10-(4-methoxyphenyl)-9-(4-nitrophenyl)-1,2,3,4,5,6,7,8,9,10-decahydroacridine-1,8-dioneContribution No. 20272019.

Acta Crystallographica Section E, 2008
The title compound, C28H28N2O5, consists of a partially hydrogenated acridine ring system with two substituted phenyl substituents on the dihydropyridine ring which are both nearly perpendicular to the mean plane of the acridine unit [dihedral angles of ...
Chunbao Miao, Changsheng Yao, Shujiang Tu, Xiaoqiang Sun   +3 more
doaj   +1 more source

Metal‐Catalyzed Benzannulation: Recent Advances in Catalyst Design, Mechanistic Insights, and Aromatic Framework Construction

The Chemical Record, EarlyView.
This review offers a contemporary overview of metal‐catalyzed benzannulation (2018–present) encompassing transition, main‐group, post‐transition, and rare‐earth‐metal catalysts. It systematically highlights catalyst design, mechanistic insights, stereo‐ and regioselectivity, and synthetic applications toward aromatic and heteroaromatic scaffolds, while
Sana Jamshaid, Divya Shrestha, Raju S. Thombal, Jeung Gon Kim, Kim Seong Cheol, Yong Rok Lee   +5 more
wiley   +1 more source

9-(4-Bromophenoxycarbonyl)-10-methylacridinium trifluoromethanesulfonate

Acta Crystallographica Section E, 2010
In the crystal structure of the title compound, C21H15BrNO2+·CF3SO3−, the cations form inversion dimers through π–π interactions between the acridine ring systems.
Damian Trzybiński, Karol Krzymiński, Artur Sikorski, Jerzy Błażejowski   +3 more
doaj   +1 more source

Effects of Roscovitine and Serum Starvation on the Viability and G0/G1 Synchronization in Somatic Cells from the Antillean Manatee (Trichechus manatus manatus, Linnaeus 1758)

Zoo Biology, EarlyView.
ABSTRACT The success of nuclear reprogramming techniques, including the G0/G1 synchronization of somatic cells, depends on species‐specific optimization. While roscovitine and serum starvation have been successfully applied in domestic and wild terrestrial mammals, their use in aquatic mammals remains poorly investigated.
Luanna Lorenna Vieira Rodrigues, Leonardo Vitorino Costa de Aquino, Lhara Ricarliany Medeiros de Oliveira, João Vitor da Silva Viana, Sarah Sant'Anna Maranhão, Maria Claudia dos Santos Luciano, Radan Elvis Matias de Oliveira, Fábia Oliveira Luna, Fernanda Loffler Niemeyer Attademo, Claudia Pessoa, Alexsandra Fernandes Pereira   +10 more
wiley   +1 more source

Degrees of Sulfonation: Mapping the Reactivity Landscape of Acridine and Acridone

Organics
Although sulfonated acridines and acridones are valuable scaffolds in diagnostics and materials science, to our best knowledge, there is no comprehensive study that addresses how the degree of sulfonation depends on reaction parameters. To fill this gap,
Péter Kisfaludi, Sára Spátay, Péter Huszthy, Ádám Golcs   +3 more
doaj   +1 more source

Associations Between Sperm DNA Fragmentation and Lifestyle Factors

Andrology, EarlyView.
ABSTRACT Background Sperm DNA fragmentation index (DFI) has been proposed as a supplementary biomarker to traditional semen parameters in the evaluation of male infertility. However, its determinants and clinical relevance remain unclear, particularly regarding modifiable lifestyle factors.
Lana Haval Mairof Adams, Lærke Priskorn, Joan‐Carles Arce, Heidi Aasted, Elisabeth Carlsen, Raphael Burkan Al‐Najaar, Anders Juul, Niels Jørgensen   +7 more
wiley   +1 more source

Structural Basis of DNA Quadruplex Recognition by an Acridine Drug

, 2016
Structural Basis of DNA Quadruplex Recognition by an Acridine ...
Stephen Neidle (9285), Nancy H. Campbell (2437195), Gary N. Parkinson (66549), Anthony P. Reszka (1970740)   +3 more
core   +1 more source

In Silico Exploration of a Symmetrical Acridine Derivative’s Anti-Alzheimer Activity: Synthesis, AChE/BuChE Binding, and ADMET Prediction

Chemistry Proceedings
Alzheimer’s disease (AD) numbers among the most precipitative neurodegenerative disorders, constituting a constant subject of interest for medicinal chemistry researchers. The treatment of such disorders remains a challenge due to the complexity of their
Yousra Ouafa Bouone, Abdeslem Bouzina, Nour-Eddine Aouf   +2 more
doaj   +1 more source

Ammonia Accumulation Drives Intervertebral Disc Degeneration by Triggering Ammonia‐Induced Cell Death Through Lysosome–Mitochondria Crosstalk

Cell Proliferation, EarlyView.
Mechanical strain disrupts the lysosome‐mitochondria axis via GLS1‐mediated ammonia toxicity, causing NP cell death and ECM breakdown in IVDD. CB839‐mediated GLS1 inhibition effectively rescues cellular homeostasis and alleviates disc degeneration.
Yang Zhang, Yucheng Gao, Shuhang Dong, Shuanggong Liu, Lei Liu, Ziyi Song, Jie Xu, Yijun Rong, Guangxu Song, Yingze Zhang, Dongjin Wu, Zengxin Gao   +11 more
wiley   +1 more source

Neomycin−Acridine Conjugate:  A Potent Inhibitor of Rev-RRE Binding

, 2016
Neomycin−Acridine Conjugate:  A Potent Inhibitor of Rev-RRE ...
Nathan W. Luedtke (1685593), Sarah R. Kirk (3008493), Yitzhak Tor (1339890)   +2 more
core   +1 more source