Results 121 to 130 of about 40,079 (224)

Progerin Hinders Autophagy Flux at Its Final Stages in Hutchinson‐Gilford Progeria Syndrome Cells, Preventing Its Own Autophagic Degradation

open access: yesAging Cell, Volume 25, Issue 8, August 2026.
We demonstrated that progerin induces the formation of autophagosomes but impairs their maturation and subsequent fusion with lysosomes. Progerin impedes proper autophagy flux, thus preventing its own autophagic degradation. Selinexor treatment improved both autophagosome maturation and autophagosome‐lysosome fusion, which ultimately led to effective ...
Ian García‐Aguirre   +18 more
wiley   +1 more source

Acridine-derived small molecule associates with VEGF and is linked to reduced CAM vascularization: a combined in silico and CAM study. [PDF]

open access: yesBMC Pharmacol Toxicol
Karmakar S   +6 more
europepmc   +1 more source

REACTION OF CARCINOGENS WITH ACRIDINE

open access: yesProceedings of the National Academy of Sciences, 1961
A, SZENT-GYORGYI, J, McLAUGHLIN
openaire   +3 more sources

Efficacy, Structure-Activity Relationship, and Mode of Action Studies of a New Generation of Acridine/Acridone-Based Antimalarials. [PDF]

open access: yesACS Infect Dis
Maluf SEC   +23 more
europepmc   +1 more source

Heterocycle-Fused Acridines

open access: yes, 1997
Groundwater, Paul W.   +1 more
openaire   +2 more sources

Sterisch überfrachtete Alken‐Photo‐Redox‐Schalter auf Basis von Chinolinium/Carben Bausteinen

open access: yesAngewandte Chemie, Volume 138, Issue 29, 13 July 2026.
Eine modulare Synthese einer neuen Klasse von Photo‐ und Redox‐Schaltern wird beschrieben, die auf der Kombination von Chinoliniumsalzen und Carbenen basiert. Das photochemische Schalten ermöglicht einen selektiven Wechsel zwischen gefalteten E/Z‐Isomeren, während das elektrochemische Schalten den Wechsel zwischen neutralen, radikalkationischen und ...
Chris Burdenski   +10 more
wiley   +1 more source

Tuneable structural and environmental factors for stability of rosette nanotubes. [PDF]

open access: yesNanoscale Adv
Hemraz UD   +4 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy