Results 121 to 130 of about 53,333 (203)
Glial Dysfunction and Memory Impairments in a Model of Pediatric Obstructive Sleep Apnea
Glia, Volume 74, Issue 11, November 2026.Generation and analysis of an snRNA‐seq atlas of the hippocampus in POSA. Validation of reduced protein expression of six genes across four cell types. Cellular‐level investigation of aberrant glial function in POSA using transgenic reporter mice. ABSTRACT Pediatric obstructive sleep apnea (POSA) is a common childhood disease that often causes aberrant
Michael R. Williamson +13 more
wiley +1 more source
, 1984 The crystal structure of acridine orange hydroiodide and that of acridine orange hydrochloride monohydrate have been solved by X-ray diffraction analysis.
MATTIA, Carlo +3 more
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Targeting lysosomes by design: novel N-acridine thiosemicarbazones that enable direct detection of intracellular drug localization and overcome P-glycoprotein (Pgp)-mediated resistance [PDF]
Innovative N-acridine thiosemicarbazones (NATs) were designed along with their iron(iii), copper(ii), and zinc(ii) complexes. Lysosomal targeting was promoted by specifically incorporating the lysosomotropic Pgp substrate, acridine, into the ...
Chen, Yanbing +11 more
core +1 more source
Journal of Applied Toxicology, Volume 46, Issue 11, Page 3804-3813, November 2026.ABSTRACT The present study aimed to quantify pesticide residues in environmental matrices and plasma and to evaluate their potential effects on oxidative stress and DNA damage in rural populations of Santa Fe province. Soil and rainwater samples were collected, and biological samples and semistructured surveys were obtained from volunteers in three ...
María Priscila Dechiara +4 more
wiley +1 more source
Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.Effects of thyroxine (T) and nano‐melatonin (NM) supplementation on cryopreserved Simmental bull semen were evaluated. The combination of thyroxine (0.5 µg/dL) and nano‐melatonin (30 µg/dL) significantly improved post‐thaw sperm motility, membrane integrity, antioxidant status, and fertility while reducing oxidative stress and apoptosis. These findings
Marwa Abonagy +18 more
wiley +1 more source
Synthetic Strategies for the Construction of Cyclobutane‐Fused Heterocycles
European Journal of Organic Chemistry, Volume 29, Issue 40, 27 October 2026.Cyclobutane‐fused heterocycles are important motifs commonly present in bioactive compounds, recognized for their rigid 3D structures that confer unique properties. However, synthesizing these compounds remains challenging. This review discusses current methods for their synthesis, such as photochemical, metal‐catalyzed, and Lewis acid‐mediated [2 + 2]
Michela Vargiu +2 more
wiley +1 more source
Tumour Inhibitory Acridine Derivatives [PDF]
Increased antitumour selectivity may be expected from the combination of radiotherapy and cancer chemotherapy. Radiosensitizing agents which have been employed for this purpose are reviewed in the first chapter.
Wong, Cho K.
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A Portal‐Preorganized Cucurbit[7]uril‐Ruthenium Conjugate Enables Motif‐Selective Protein Sensing
Angewandte Chemie International Edition, Volume 65, Issue 44, 26 October 2026.Reprogramming cucurbit[7]uril (CB7) recognition through portal engineering transforms an optically silent host into a motif‐selective photoluminescent receptor. The portal‐preorganized CB7‐Rubpy conjugate directly reports changes in aromatic motif accessibility, enabling optical sensing of protein misfolding and refolding.
Patrick Gruhs +10 more
wiley +1 more source
Chemistry – A European Journal, Volume 32, Issue 39, 22 October 2026.A comprehensive experimental and theoretical study is presented of a family of TADF dyes. Comparing the behavior of structurally related dyes, we uncover the subtle and somewhat unexpected role of conformational degrees of freedom associated with peripheral groups that affect the delicate interplay of excited states that governs spin–orbit coupling ...
Andrea Landi +7 more
wiley +1 more source
Chemistry – A European Journal, Volume 32, Issue 39, 22 October 2026.A library of 21 tetrakis(phenothiazinyl)‐substituted silanes with broadly variable substituent decoration, which are fully reversible multistage redox systems with intense tunable emission from deep blue to yellow–green (441–533 nm), was rapidly synthesized by bromine–lithium exchange/borylation–Suzuki coupling of tetrakis(4‐bromophenyl)silane or by ...
Thomas P. M. Merke +4 more
wiley +1 more source