Results 131 to 140 of about 69,662 (247)
Proposed signaling pathway by which TY modulates NLRP3/Caspase‐1/GSDMD‐mediated pyroptosis. ABSTRACT This research focuses on exploring the modulation of pyroptosis and its underlying mechanisms via the “Tianyu” formulation (TY), a traditional Chinese medicine, in human rheumatoid arthritis fibroblast‐like synovial cells (RA‐HFLS) and a collagen ...
Yueya Zhu +5 more
wiley +1 more source
Stains Induce Apoptosis and Autophagy in Primary and Transformed Mast Cells [PDF]
Statin drugs are widely employed in the clinic to reduce serum low density lipoproteins (LDLs) in patients with hypocholesteremia. In addition to their cholesterol-lowering effects through HMG CoA reductase antagonism, isoprenyl lipids necessary for ...
Paez, Patrick A
core +1 more source
The efficacy of the novel anti‐tau active immunotherapy, p5555kb, was tested using two mouse models of tau pathology. p5555kb inoculation increased the survival rate and reduced tau pathology in tau‐overexpressing P301L mice and decreased tau seeding in the brains of C57BL/6 mice injected with human‐purified Alzheimer's disease tau.
Christopher M. Brown +7 more
wiley +1 more source
Determination of Cell Viability—Acridine Orange/Propidium Iodide (AO/PI) Staining Method
Cell Proliferation, EarlyView.
Lei Wang +29 more
wiley +1 more source
Staggered, square, and heavily bent dimers occur in the five known solvatomorphs of paddlewheel (PW) complex [PtVO(SOCPh)4]. These and other structural motifs are well within energetic reach due to the shallow potential energy surface that guides dimerization and are included in a revised classification of available structural data on heterobimetallic ...
Olga Mironova +3 more
wiley +1 more source
Prolongation of AV nodal refractoriness by Ruta graveolens in isolated rat hearts [PDF]
Objectives: To evaluate concentration-dependent effects of total extract of Rusta graveolens and its purified alkaloid fraction on the nodal basic and functional properties.
Golalipour, M.J. +4 more
core
Alix and VPS4A function in HBV biogenesis and degradation in the context of the endosomal and autophagic pathways. Alix and VPS4A orchestrate HBV secretion and degradation via endosomal and autophagic pathways. Under normal conditions, ESCRT ensures efficient virion budding and MVB formation.
Jia Li +5 more
wiley +1 more source
Aqueous micellar catalysis using industrially sourced rhamnolipids enables efficient Pd‐catalyzed N‐arylation of o‐acylanilines at 40°C. This surfactant‐driven system offers a sustainable and more efficient alternative to organic solvents, combining broad substrate scope, low catalyst loading, and enhanced energy efficiency.
Attila R. Herczegh +3 more
wiley +1 more source
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj +21 more
wiley +1 more source

