Results 111 to 120 of about 69,662 (247)

Microfluidic Intracytoplasmic Sperm Injection (MICSI): A Novel Platform for Sperm Isolation, Selection, and Injection Into Oocytes

open access: yesAndrology, EarlyView.
ABSTRACT Background Infertility is a pressing global health concern, affecting one in six couples worldwide. The failure rate for assisted reproductive technologies (ART) cycles remains at approximately 78%, with limited improvements often attributed to a lack of technological innovation.
Mehran Dabiri   +3 more
wiley   +1 more source

9-(4-Bromophenoxycarbonyl)-10-methylacridinium trifluoromethanesulfonate

open access: yesActa Crystallographica Section E, 2010
In the crystal structure of the title compound, C21H15BrNO2+·CF3SO3−, the cations form inversion dimers through π–π interactions between the acridine ring systems.
Damian Trzybiński   +3 more
doaj   +1 more source

Measuring Propidium Iodide Brightness as a Function of Viability: A High‐Throughput Quantitative Assessment of Hepatic Spheroids

open access: yesArtificial Organs, EarlyView.
The graphical abstract illustrates our rapid PI‐based spheroid viability assay: hepatocyte spheroids are formed and stained with AO/PI, imaged after a 15‐min incubation, and analyzed for PI brightness normalized to area. This metric correlates strongly with functional urea/DNA output, validating PI intensity as a fast, reliable indicator of spheroid ...
Michael G. Megaly   +11 more
wiley   +1 more source

A spectroscopic study of interaction of cationic dyes with heparin

open access: yesOrbital: The Electronic Journal of Chemistry, 2010
The interaction of two cationic dyes namely, acridine orange and pinacyanol chloride with an anionic polyelectrolyte, heparin, has been investigated by spectrophotometric method.The polymer induced metachromasy in the dyes resulting in the shift of the ...
R. Nandini, B. Vishalakshi
doaj   +1 more source

Use of parallel fluorescent confocal microscopy for detection of prostatic adenocarcinoma

open access: yesBJU International, EarlyView.
Objective To provide a histological catalogue and defined criteria for the diagnosis of prostatic adenocarcinoma and its variants using the fluorescent confocal microscope (FCM) platform. Methods A total of 22 radical prostatectomy specimens were serially sectioned and scanned with the FCM.
Kevin Clare   +13 more
wiley   +1 more source

Same‐day fluorescence confocal microscopy of MRI‐targeted prostate biopsies: A feasibility study

open access: yesBJU International, EarlyView.
Objectives To determine the diagnostic performance of ex vivo fluorescence confocal microscopy (FCM) for prostate cancer detection in magnetic resonance imaging (MRI)‐targeted biopsy specimens using final histopathology as the reference standard, and to quantify workflow component times relevant to same‐day implementation.
Salim K. Younis   +13 more
wiley   +1 more source

Degrees of Sulfonation: Mapping the Reactivity Landscape of Acridine and Acridone

open access: yesOrganics
Although sulfonated acridines and acridones are valuable scaffolds in diagnostics and materials science, to our best knowledge, there is no comprehensive study that addresses how the degree of sulfonation depends on reaction parameters. To fill this gap,
Péter Kisfaludi   +3 more
doaj   +1 more source

Ex vivo fluorescence confocal microscopy for assessment of ureteroscopic biopsy adequacy in upper tract urothelial carcinoma

open access: yesBJU International, EarlyView.
Objectives To evaluate the feasibility of ex vivo fluorescence confocal microscopy (FCM) for real‐time assessment of ureteroscopic biopsy specimen adequacy in patients with suspected upper tract urothelial carcinoma (UTUC). Patients and Methods In this prospective, single‐centre feasibility study, four ureteroscopic biopsy specimens obtained from two ...
Karim Daher   +14 more
wiley   +1 more source

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

open access: yesJournal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah   +8 more
wiley   +1 more source

ACRIDINE DERIVATIVES. PART V. AUROTHlO- AND ARGENTOTHIO-ACRIDINES.

open access: yes, 1940
Gold and silver compounds of 5-thiolacridine derivatives have been described.
openaire   +1 more source

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