Results 131 to 140 of about 601 (168)

Design and Synthesis of Modified Quinolones as Antitumoral Acridones

Journal of Medicinal Chemistry, 1999
The bacterial topoisomerase II (DNA gyrase) and the mammalian topoisomerase II represent the cellular targets for quinolone antibacterials and a wide variety of anticancer drugs, respectively. In view of the mechanistic similarities and sequence homologies exhibited by the two enzymes, tentative efforts to selectively shift from an antibacterial to an ...
TABARRINI, Oriana, CECCHETTI, Violetta, FRAVOLINI, Arnaldo, NOCENTINI, Giuseppe, Barzi A., SABATINI, STEFANO, Miao H., Sissi C.   +7 more
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Mass Spectra of Acridone Alkaloids

Journal of the Chinese Chemical Society, 1989
AbstractThe mass spectra of a variety of simple acridones, prenylacridones, pyranoacridones, dihydropyranoacridones, and furoacridones are presented and discussed. The results illustrate that the characteristic fragmentation patterns are of considerable utility in the application of mass spectrometry to structure elucidation in the acridone alkaloids.
Shaw‐Tao Lin, Tian‐Shung Wu
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9-Acridone from 2,2′-diaminobenzophenone

J. Chem. Soc. C, 1966
9-Acridone and 3,6-dichloro-9-acridone have been prepared in high yields by treatment of the corresponding 2,2′-diaminobenzophenones with 100% phosphoric acid. Boiling hydrochloric acid does not effect these cyclisations.
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Biomimetic synthesis of acridone alkaloids

Journal of the Chemical Society, Perkin Transactions 1, 1977
Cyclisations of 2′-amino-, 2′-acetylamino-, or 2′-methylamino-2-methoxybenzophenones occur in the presence of sodium hydride in dimethyl sulphoxide to give acridone alkaloids. This cyclisation has relevance to the biosynthesis of these alkaloids. An alternative cyclisation can occur, giving 4-arylquinolines or 4-arylquinolones.
Joyce H. Adams, Padma Gupta, M. Shafiq Khan, John R. Lewis   +3 more
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Acridone Synthase: A Key Enzyme in Acridone Alkaloid Biosynthesis

Planta Medica, 1993
D. Gröger, A. Baumert, W. Maier
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Acridones

2018
Rajesh Kumar, Sarita Sharma, Deonandan Prasad   +2 more
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acridone, n.

2023
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ChemInform Abstract: ACRIDONE 35. MITT. JODIERUNG VON ACRIDON

Chemischer Informationsdienst. Organische Chemie, 1970
I. GOIA, M. IONESCU
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ACRIDONE

Organic Syntheses, 1939
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Tandem Access to Acridones and their Fused Derivatives: [1+2+3] Annulation of Isocyanides with Unsaturated Carbonyls

Advanced Synthesis and Catalysis, 2020
Ling-Juan Zhang, Zhongyan Hu, Xian-Ming Zhang   +2 more
exaly