Results 121 to 130 of about 57,421 (320)
Effects of Velagliflozin in 8 Cats With Diabetes Mellitus and Hypersomatotropism
ABSTRACT Background Velagliflozin is a sodium‐glucose cotransporter 2 inhibitor licensed for the treatment of diabetes mellitus (DM) in cats, but its use in cats with hypersomatotropism is not described. Hypothesis/Objectives To describe the use of velagliflozin in cats with DM and hypersomatotropism.
Francesca Del Baldo+6 more
wiley +1 more source
Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario Thevis+2 more
wiley +1 more source
Sclerostin levels in patients with acromegaly
Acromegaly is a rare, endocrine condition characterized by autonomous excessive secretion of growth hormone, causing numerous complications, including impairment of bone microarchitecture.
Arnika Wydra+4 more
doaj +1 more source
Characterization of Human Pituitary Adenomas in Cell Cultures by Light And Electron Microscopic Morphology And Immunolabeling [PDF]
The morphology and hormone production of pituitary adenoma cell cultures were compared in order to highlight their characteristic in vitro features. Cell suspensions were prepared from 494 surgical specimens.
Bácsy, Ernő+6 more
core
The decrease in growth hormone (GH) response after repeated stimulation with GH-Releasing hormone is partly caused by an elevation of somatostatin tonus. [PDF]
Repeated injection of GHRH leads to a decrease in the GH response in normal subjects. Arginine (Arg) stimulates GH secretion by suppression of hypothalamic somatostatin.
Mehltretter, Gerhard+5 more
core +1 more source
Peptide Drug: Design and Clinical Applications
The diagram illustrates the role of poly peptides in various biological processes. It highlights their involvement in glucose, lipid, and amino acid metabolism, as well as in antitumor and antiviral immunity. Additionally, poly peptides are linked to disease diagnosis and prognosis, emphasizing their significance in healthcare.
Yaqi Han+4 more
wiley +1 more source
Expression of microRNA related to bone remodeling regulation in plasma in patients with acromegaly
Backgraund. MiсroRNA are small regulatory factors that regulate gene expression by post-transcriptional regulation of mRNA, playing an important role in numerous cellular processes including organogenesis, apoptosis, cell proliferation and ...
Tatiana A. Grebennikova+6 more
doaj +1 more source
In our previous publication, it was shown that growth hormone (GH) excess in acromegaly affects the cell integrity of somatic cells through increased DNA damage throughout the body and impaired DNA repair pathways.
Abdalla Elbialy+4 more
doaj +1 more source
Abstract Aberrant human growth hormone (GH) expression has been increasingly linked to poor outcomes in certain cancers and reduced health span. GH receptor (GHR) signal transduction activates signaling pathways that promote cell proliferation and survival, contributing to tumor progression.
Yue Wang+5 more
wiley +1 more source
Machine Learning-Based Radiomics Predicts Radiotherapeutic Response in Patients With Acromegaly
Background: Prediction of radiotherapeutic response before radiotherapy could help determine individual treatment strategies for patients with acromegaly.
Yanghua Fan+5 more
semanticscholar +1 more source