Results 121 to 130 of about 57,421 (320)

Effects of Velagliflozin in 8 Cats With Diabetes Mellitus and Hypersomatotropism

open access: yesJournal of Veterinary Internal Medicine, Volume 39, Issue 5, September/October 2025.
ABSTRACT Background Velagliflozin is a sodium‐glucose cotransporter 2 inhibitor licensed for the treatment of diabetes mellitus (DM) in cats, but its use in cats with hypersomatotropism is not described. Hypothesis/Objectives To describe the use of velagliflozin in cats with DM and hypersomatotropism.
Francesca Del Baldo   +6 more
wiley   +1 more source

Annual Banned‐Substance Review 17th Edition—Analytical Approaches in Human Sports Drug Testing 2023/2024

open access: yesDrug Testing and Analysis, Volume 17, Issue 8, Page 1417-1442, August 2025.
Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario  Thevis   +2 more
wiley   +1 more source

Sclerostin levels in patients with acromegaly

open access: yesEndokrynologia Polska
Acromegaly is a rare, endocrine condition characterized by autonomous excessive secretion of growth hormone, causing numerous complications, including impairment of bone microarchitecture.
Arnika Wydra   +4 more
doaj   +1 more source

Characterization of Human Pituitary Adenomas in Cell Cultures by Light And Electron Microscopic Morphology And Immunolabeling [PDF]

open access: yes, 2005
The morphology and hormone production of pituitary adenoma cell cultures were compared in order to highlight their characteristic in vitro features. Cell suspensions were prepared from 494 surgical specimens.
Bácsy, Ernő   +6 more
core  

The decrease in growth hormone (GH) response after repeated stimulation with GH-Releasing hormone is partly caused by an elevation of somatostatin tonus. [PDF]

open access: yes, 1996
Repeated injection of GHRH leads to a decrease in the GH response in normal subjects. Arginine (Arg) stimulates GH secretion by suppression of hypothalamic somatostatin.
Mehltretter, Gerhard   +5 more
core   +1 more source

Peptide Drug: Design and Clinical Applications

open access: yesMedComm, Volume 6, Issue 8, August 2025.
The diagram illustrates the role of poly peptides in various biological processes. It highlights their involvement in glucose, lipid, and amino acid metabolism, as well as in antitumor and antiviral immunity. Additionally, poly peptides are linked to disease diagnosis and prognosis, emphasizing their significance in healthcare.
Yaqi Han   +4 more
wiley   +1 more source

Expression of microRNA related to bone remodeling regulation in plasma in patients with acromegaly

open access: yesОжирение и метаболизм, 2017
Backgraund. MiсroRNA are small regulatory factors that regulate gene expression by post-transcriptional regulation of mRNA, playing an important role in numerous cellular processes including organogenesis, apoptosis, cell proliferation and ...
Tatiana A. Grebennikova   +6 more
doaj   +1 more source

An Acromegaly Disease Zebrafish Model Reveals Decline in Body Stem Cell Number along with Signs of Premature Aging

open access: yesBiology, 2020
In our previous publication, it was shown that growth hormone (GH) excess in acromegaly affects the cell integrity of somatic cells through increased DNA damage throughout the body and impaired DNA repair pathways.
Abdalla Elbialy   +4 more
doaj   +1 more source

Growth hormone receptor antagonists, GHA2 and GHA3, with dual activity against the human and mouse receptor

open access: yesProtein Science, Volume 34, Issue 8, August 2025.
Abstract Aberrant human growth hormone (GH) expression has been increasingly linked to poor outcomes in certain cancers and reduced health span. GH receptor (GHR) signal transduction activates signaling pathways that promote cell proliferation and survival, contributing to tumor progression.
Yue Wang   +5 more
wiley   +1 more source

Machine Learning-Based Radiomics Predicts Radiotherapeutic Response in Patients With Acromegaly

open access: yesFrontiers in Endocrinology, 2019
Background: Prediction of radiotherapeutic response before radiotherapy could help determine individual treatment strategies for patients with acromegaly.
Yanghua Fan   +5 more
semanticscholar   +1 more source

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