Results 171 to 180 of about 3,330 (184)

Equatorial segment protein defines a discrete acrosomal subcompartment persisting throughout acrosomal biogenesis.

Biology of reproduction, 2004
The equatorial segment of the acrosome underlies the domain of the sperm that fuses with the egg membrane during fertilization. Equatorial segment protein (ESP), a novel 349-amino acid concanavalin-A-binding protein encoded by a two-exon gene (SP-ESP) located on chromosome 15 at q22, has been localized to the equatorial segment of ejaculated human ...
Michael J, Wolkowicz, Jagathpala, Shetty, Anne, Westbrook, Ken, Klotz, Frederike, Jayes, Arabinda, Mandal, Charles J, Flickinger, John C, Herr   +7 more
openaire   +1 more source

Human acrosome biogenesis: immunodetection of proacrosin in primary spermatocytes and of its partitioning pattern during meiosis

Development, 1991
ABSTRACT Proacrosin biosynthesis timing during human spermatogenesis has been studied using the monoclonal antibody 41)4 (mAb 4D4). Frozen and paraffin-embedded sections of testicular biopsies were labelled by standard indirect immunofluorescence and avidin-biotin immunoperoxidase procedures.
D, Escalier, J M, Gallo, M, Albert, G, Meduri, D, Bermudez, G, David, J, Schrevel   +6 more
openaire   +2 more sources

C-terminal kinesin motor KIFC1 participates in acrosome biogenesis and vesicle transport.

Biology of reproduction, 2004
We have identified a possible role for the KIFC1 motor protein in formation of the acrosome, an organelle unique to spermatogenesis. KIFC1, a C-terminal kinesin motor, first appears on membrane-bounded organelles (MBOs) in the medulla of early spermatids followed by localization to the acrosomal vesicle. KIFC1 continues to be present on the acrosome of
Wan-Xi, Yang, Ann O, Sperry
openaire   +1 more source

Acrosome biogenesis and perinuclear theca defects in globozoospermia

Fertility and Sterility, 2012
C. Alvarez Sedó, G. Alvarez, V.Y. Rawe, H. Chemes   +3 more
openaire   +1 more source

Relationship between UBPy and the Endosome System in Acrosome Biogenesis

2009
Summary. One of the major events that characterize spermiogenenesis is the formation of the acrosome. Acrosome-less spermatozoa are infertile; in human, globozoospermia is a rare but severe disorder in male infertility. The acrosome formation is far more complicated than has been so far proposed.
openaire   +1 more source

Human globozoospermia‐related genes and their role in acrosome biogenesis

WIREs Mechanisms of Disease, 2023
Ricardo D Moreno
exaly  

IZUMO family member 3, IZUMO3, is involved in male fertility through the acrosome formation

Molecular Reproduction and Development, 2021
Naokazu Inoue, Yuhkoh Satouh, Ikuo Wada
exaly  

Biogenesis of sperm acrosome is regulated by pre-mRNA alternative splicing ofAcrbpin the mouse

Proceedings of the National Academy of Sciences of the United States of America, 2016
woojin Kang, Shin-Ichi Kashiwabara, Masahito Ikawa   +2 more
exaly  

Dynamic of contribution of UBPy-sorted cargo to acrosome biogenesis: effects of its derailment in a mouse model of globozoospermia, the infertile Vps54 (L967Q) mutant

Cell and Tissue Research, 2017
Maria E Pasini, Giovanna Berruti
exaly  

Faculty Opinions recommendation of Loss of zona pellucida binding proteins in the acrosomal matrix disrupts acrosome biogenesis and sperm morphogenesis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2007
openaire   +1 more source