Results 71 to 80 of about 5,280,557 (249)
In vitro Induction and Detection of Acrosomal Exocytosis in Human Spermatozoa
Bio-Protocol, 2020 The acrosome reaction is a highly regulated exocytotic event that primes spermatozoa for successful fertilization. Upon induction, acrosomal exocytosis proceeds via a wave of vesiculation that radiates across the sperm head, destabilizing the acrosomal ...
Shenae Cafe +2 more
doaj +1 more source
Identification and function of exchange proteins activated directly by cyclic AMP (Epac) in mammalian spermatozoa. [PDF]
PLoS ONE, 2012 The role of cAMP in spermatic functions was classically thought to be mediated exclusively through the activation of Protein Kinase A (PKA). However, it has recently been shown that cAMP also exerts its effects through a PKA-independent pathway ...
Alvaro Miro-Moran +6 more
doaj +1 more source
Multiple Roles of Protamine Kinase SRPK1 and Phosphatase PP1γ in Sperm Development
PROTEOMICS, EarlyView.ABSTRACT Protein phosphorylation regulates key events of male germ cell differentiation. In the testis, SRPK1 and PP1γ are involved in protamine phosphorylation and dephosphorylation, respectively, and their deregulation is linked to defective chromatin structure and male infertility.
Alberto de la Iglesia +7 more
wiley +1 more source
Zn2+-stimulation of sperm capacitation and of the acrosome reaction is mediated by EGFR activation.
Developmental Biology, 2014 Extracellular zinc regulates cell proliferation via the MAP1 kinase pathway in several cell types, and has been shown to act as a signaling molecule.
Y. Michailov +2 more
semanticscholar +1 more source
Environmental Toxicology, EarlyView.ABSTRACT Plastic, with its remarkable versatility and numerous applications, has greatly benefited humanity. However, its extreme resistance to natural degradation means it persists in the environment for long periods, causing global environmental problems.
Teresa Chianese +13 more
wiley +1 more source
Citation: 'acrosome reaction' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10334 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
Fahmi Bahar, Tan V. Le
openaire +2 more sources
Reproductive Biology and Endocrinology, 2009 Background In rodents, the cell surface complement regulatory protein CD46 is expressed solely on the spermatozoal acrosome membrane. Ablation of the CD46 gene is associated with a faster acrosome reaction.
Flanagan Brian F +7 more
doaj +1 more source
In-vitro application of pentoxifylline preserved ultrastructure of spermatozoa after vitrification in asthenozoospermic patients [PDF]
, 2017 PURPOSE: To evaluate the effect of in vitro application of pentoxifylline (PX) on sperm parameters and ultrastructure after vitrification in asthenozoospermic patients. MATERIALS AND METHODS: A total of 30 asthenozoospermic semen samples (aged 25-45
Khalili, Ma +7 more
core
Molecular evolution of candidate male reproductive genes in the brown algal model Ectocarpus [PDF]
, 2016 Background: Evolutionary studies of genes that mediate recognition between sperm and egg contribute to our understanding of reproductive isolation and speciation. Surface receptors involved in fertilization are targets of sexual selection, reinforcement,
De Clerck, Olivier +2 more
core +6 more sources
Andrology, EarlyView.ABSTRACT Background More than 1000 genes have been identified as predominantly expressed in the human testis. Advances in gene editing technologies have enabled the rapid and efficient generation of genetically engineered mice. This approach facilitates the screening of genes essential for spermatogenesis by analyzing knockout mouse models.
Yumiao Qiu +2 more
wiley +1 more source