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Toxicology of acrylamide

Toxicology and Applied Pharmacology, 1964
Abstract This laboratory became interested in acrylamide early in 1954, when it became apparent that the material had great potential as a monomer and comonomer to make resins with unique flocculating action, and later as a dry strength improver in the manufacture of paper and paperboard.
D D, MCCOLLISTER, F, OYEN, V K, ROWE
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Acrylamide and thiamine

Archives of Toxicology, 1989
Acrylamide administration to rats caused clear alteration of blood thiamine content, which appeared to reflect suppressed intake and/or utilization of the vitamin in the body. Decreased utilization of thiamine does not seem to be induced by decreased binding of thiamine pyrophosphate (TPP) and apotransketolase, because acrylamide did not affect the Km ...
H, Igisu, I, Goto
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The carcinogenicity of acrylamide

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2005
Acrylamide is carcinogenic to experimental mice and rats, causing tumors at multiple organ sites in both species when given in drinking water or by other means. In mice, acrylamide increases the incidence of alveologenic lung tumors and initiates skin tumors after dermal exposures.
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Acrylamide Carcinogenicity

Journal of Agricultural and Food Chemistry, 2008
The induction of cancer by chemicals is a multiple-stage process. Acrylamide is carcinogenic to experimental mice and rats, causing tumors at multiple organ sites in both species when given in drinking water or by other means. In mice, acrylamide increased the incidence and multiplicity of lung tumors and skin tumors.
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Acrylamide axonopathy revisited

Toxicology and Applied Pharmacology, 2003
Distal swelling and eventual degeneration of axons in the CNS and PNS have been considered to be the characteristic neuropathological features of acrylamide (ACR) neuropathy. These axonopathic changes have been the basis for classifying ACR neuropathy as a central-peripheral distal axonopathy and, accordingly, research over the past 30 years has ...
R M, LoPachin, C D, Balaban, J F, Ross
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Acrylamide

2016
Acrylamide is a compound that is formed through the Maillard reaction from the reaction between free asparagine and carbonyl compounds (mainly reducing sugars) during heating at temperatures >. 120. °C of plant-derived, carbohydrate-rich foods such as French fries, potato chips, bakery products, and coffee.
Capuano, E., Fogliano, V.
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The Mechanisms of Acrylamide Axonopathy

Annual Review of Pharmacology and Toxicology, 1985
Degeneration of the distal axons of long and large-diameter peripheral nerve fibers is perhaps the most common of all toxic peripheral nerve disorders. Degeneration commonly spreads centrally along affected nerve tracts in a dying-back fashion (1).
M S, Miller, P S, Spencer
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Colorimetric and visual determination of acrylamide via acrylamide-mediated polymerization of acrylamide-functionalized gold nanoparticles

Microchimica Acta, 2018
A colorimetric assay is described for acrylamide (AA). It is based on color changes induced by an increase in the distance between gold nanoparticles (AuNPs) that is caused by AA copolymerization. First, AuNPs were modified with a thiolated propylene amide poly(ethylene glycol) that also contains the AA functionality.
Xingbo Shi   +7 more
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Acrylamide in Austrian foods

Journal of Biochemical and Biophysical Methods, 2004
Acrylamide is known for its potential health hazards. Recently acrylamide was found in starch containing heated foods in high concentrations which lead to the assumption that a cancer risk could be associated with the uptake of foods containing high amounts of acrylamide.
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