Comparison of Cortisol and ACTH Responses after Administration of Thyrotropin Releasing Hormone in Normal Horses and Those with Pituitary Pars Intermedia Dysfunction [PDF]
Journal of Veterinary Internal Medicine, 2011 Jill Beech +2 more
openalex +2 more sources
Journal of the Endocrine Society, 2021 Context The normal cortisol response 30 or 60 minutes after cosyntropin (ACTH[1–24]) is considered to be ≥18 μg/dL (500 nmol/L). This threshold is based on older serum cortisol assays.
B. Javorsky +6 more
semanticscholar +1 more source
Dynamics of ACTH and Cortisol Secretion and Implications for Disease
Endocrine reviews, 2020 The past decade has seen several critical advances in our understanding of hypothalamic–pituitary–adrenal (HPA) axis regulation. Homeostatic physiological circuits need to integrate multiple internal and external stimuli and provide a dynamic output ...
S. Lightman +2 more
semanticscholar +1 more source
ACTH more than 2000 pg/ml; is it immunoassay interference or another matter?
Journal of Pathology of Nepal, 2023 Starting rifampicin in patients with Addison’s disease or adrenal tuberculosis may precipitate an adrenal crisis as a result of the induction of CYP 3A4 which in turn leads to increased breakdown of cortisol.
Vivek Pant, Santosh Pradhan
doaj +1 more source
Laporan kasus berbasis bukti: Efektivitas Kortikosteroid dalam Pengobatan Spasme Infantil
Sari Pediatri, 2022 Latar belakang. Spasme infantil (SI) adalah suatu sindrom epilepsi berat dengan awitan masa bayi. Hormon adrenokortikotropik(ACTH) merupakan obat utama pada SI.
Teti Hendrayani +3 more
doaj +1 more source
Disease Models & Mechanisms, 2020 X-linked infantile spasms syndrome (ISSX) is a clinically devastating developmental epileptic encephalopathy with life-long impact. Arx(GCG)10+7, a mouse model of the most common triplet-repeat expansion mutation of ARX, exhibits neonatal spasms ...
Meagan S. Siehr +2 more
doaj +1 more source
Repeated restraint stress induced neurobehavioral and sexual hormone disorders in male rats
AIMS Neuroscience, 2022 Several studies have demonstrated that depression include disruptions not only for mental human disorders but also their healthy living. Rodent-based behavioral tests and models are widely used to understand the mechanisms by which stress triggers ...
Ahlem Matallah +2 more
doaj +1 more source
Gel chromatographic characterization of immunoreactive adrenocorticotropin in patients with ACTH hypersecretion [PDF]
, 1989 We investigated the molecular size of circulating immunoreactive ACTH by gel chromatography in patients with ACTH hypersecretion due to various disorders of the hypothalamic-pituitary-adrenal axis.
A Chatelain +19 more
core +1 more source
Does an Analysis of the Pulsatile Secretion Pattern of Adrenocorticotropin and Cortisol Predict the Result of Transsphenoidal Surgery in Cushing’s Disease. [PDF]
, 1993 The endocrinological, surgical, and histological findings of patients with ACTH-dependent Cushing's disease were correlated with the pulsatile secretion pattern of ACTH and cortisol and the outcome after transsphenoidal pituitary surgery.
Brabant, Georg +5 more
core +1 more source
Journal of the Endocrine Society, 2019 The proper clinical evaluation of pituitary and adrenal disorders depends on the accurate measurement of plasma ACTH. The modern two-site sandwich ACTH immunoassay is a great improvement compared with older methods but still has the potential for ...
L. Greene +4 more
semanticscholar +1 more source