Results 1 to 10 of about 976,237 (341)

A mitochondria-anchored isoform of the actin-nucleating spire protein regulates mitochondrial division

open access: yeseLife, 2015
Mitochondrial division, essential for survival in mammals, is enhanced by an inter-organellar process involving ER tubules encircling and constricting mitochondria.
Uri Manor   +7 more
doaj   +2 more sources

SARM1 Suppresses Axon Branching Through Attenuation of Axonal Cytoskeletal Dynamics

open access: yesFrontiers in Molecular Neuroscience, 2022
Axon branching is a fundamental aspect of neuronal morphogenesis, neuronal circuit formation, and response of the nervous system to injury. Sterile alpha and TIR motif containing 1 (SARM1) was initially identified as promoting Wallerian degeneration of ...
Andrea Ketschek   +3 more
doaj   +1 more source

Cross Talk between ARF1 and RhoA Coordinates the Formation of Cytoskeletal Scaffolds during Chlamydia Infection

open access: yesmBio, 2021
Chlamydia trachomatis is an obligate intracellular bacterium that has developed sophisticated mechanisms to survive inside its infectious compartment, the inclusion. Notably, Chlamydia weaves an extensive network of microtubules (MTs) and actin filaments
Adam Haines   +4 more
doaj   +1 more source

mDia1 Assembles a Linear F-Actin Coat at Membrane Invaginations To Drive Listeria monocytogenes Cell-to-Cell Spreading

open access: yesmBio, 2021
Direct cell-to-cell spreading of Listeria monocytogenes requires the bacteria to induce actin-based finger-like membrane protrusions in donor host cells that are endocytosed through caveolin-rich membrane invaginations by adjacent receiving cells.
Aaron S. Dhanda   +4 more
doaj   +1 more source

Fundamental in vitro 3D human skin equivalent tool development for assessing biological safety and biocompatibility – towards alternative for animal experiments

open access: yes4 open, 2021
Nowadays, human skin constructs (HSCs) are required for biomaterials, pharmaceuticals and cosmetics in vitro testing and for the development of complex skin wound therapeutics.
Idrees Ayesha   +9 more
doaj   +1 more source

Functional Role of Class III Myosins in Hair Cells

open access: yesFrontiers in Cell and Developmental Biology, 2021
Cytoskeletal motors produce force and motion using the energy from ATP hydrolysis and function in a variety of mechanical roles in cells including muscle contraction, cargo transport, and cell division.
Joseph A. Cirilo   +2 more
doaj   +1 more source

Anti-phospholipase A2 receptor antibodies directly induced podocyte damage in vitro

open access: yesRenal Failure, 2022
Background The pathogenesis of primary membranous nephropathy (MN) involves the antibodies against antigens on the cell surface of podocytes, with the majority of M-type phospholipase A2 receptor (PLA2R), and a profound podocyte dysfunction.
Yanfen Li   +4 more
doaj   +1 more source

Cytoskeletal architecture and its evolutionary significance in amoeboid eukaryotes and their mode of locomotion [PDF]

open access: yesRoyal Society Open Science, 2016
The cytoskeleton is the hallmark of eukaryotic evolution. The molecular and architectural aspects of the cytoskeleton have been playing a prominent role in our understanding of the origin and evolution of eukaryotes. In this study, we seek to investigate
Yonas I. Tekle, Jessica R. Williams
doaj   +1 more source

ACTIN7 Is Required for Perinuclear Clustering of Chloroplasts during Arabidopsis Protoplast Culture

open access: yesPlants, 2020
In Arabidopsis, the actin gene family comprises eight expressed and two non-expressed ACTIN (ACT) genes. Of the eight expressed isoforms, ACT2, ACT7, and ACT8 are differentially expressed in vegetative tissues and may perform specific roles in ...
Michael B. Sheahan   +3 more
doaj   +1 more source

Frequent Manipulation of Resistance Training Variables Promotes Myofibrillar Spacing Changes in Resistance-Trained Individuals

open access: yesFrontiers in Physiology, 2021
We sought to determine if manipulating resistance training (RT) variables differentially altered the expression of select sarcoplasmic and myofibril proteins as well as myofibrillar spacing in myofibers.
Carlton D. Fox   +14 more
doaj   +1 more source

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