Results 1 to 10 of about 61,431 (266)
Wrangling Actin Assemblies: Actin Ring Dynamics during Cell Wound Repair
Cells, 2022 To cope with continuous physiological and environmental stresses, cells of all sizes require an effective wound repair process to seal breaches to their cortex.
Justin Hui +3 more
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Competition between myosin II and βH-spectrin regulates cytoskeletal tension
eLife, 2023 Spectrins are membrane cytoskeletal proteins generally thought to function as heterotetramers comprising two α-spectrins and two β-spectrins. They influence cell shape and Hippo signaling, but the mechanism by which they influence Hippo signaling has ...
Consuelo Ibar +3 more
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Anti-phospholipase A2 receptor antibodies directly induced podocyte damage in vitro
Renal Failure, 2022 Background The pathogenesis of primary membranous nephropathy (MN) involves the antibodies against antigens on the cell surface of podocytes, with the majority of M-type phospholipase A2 receptor (PLA2R), and a profound podocyte dysfunction.
Yanfen Li +4 more
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SARM1 Suppresses Axon Branching Through Attenuation of Axonal Cytoskeletal Dynamics
Frontiers in Molecular Neuroscience, 2022 Axon branching is a fundamental aspect of neuronal morphogenesis, neuronal circuit formation, and response of the nervous system to injury. Sterile alpha and TIR motif containing 1 (SARM1) was initially identified as promoting Wallerian degeneration of ...
Andrea Ketschek +3 more
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Bacterial nucleators: actin' on actin [PDF]
Pathogens and Disease, 2015 The actin cytoskeleton is a key target of numerous microbial pathogens, including protozoa, fungi, bacteria and viruses. In particular, bacterial pathogens produce and deliver virulence effector proteins that hijack actin dynamics to enable bacterial invasion of host cells, allow movement within the host cytosol, facilitate intercellular spread or ...
Irina Saraiva Franco +2 more
openaire +3 more sources
Tugging at the Heart Strings: The Septin Cytoskeleton in Heart Development and Disease
Journal of Cardiovascular Development and Disease, 2020 Septin genes were originally identified in budding yeast in 1971. Since their original discovery, at least 13 mammalian genes have now been found, which give rise to a vast array of alternatively spliced proteins that display unique spatial-temporal ...
Kelsey Moore +3 more
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mBio, 2021 Chlamydia trachomatis is an obligate intracellular bacterium that has developed sophisticated mechanisms to survive inside its infectious compartment, the inclusion. Notably, Chlamydia weaves an extensive network of microtubules (MTs) and actin filaments
Adam Haines +4 more
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mBio, 2021 Direct cell-to-cell spreading of Listeria monocytogenes requires the bacteria to induce actin-based finger-like membrane protrusions in donor host cells that are endocytosed through caveolin-rich membrane invaginations by adjacent receiving cells.
Aaron S. Dhanda +4 more
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Frontiers in Physiology, 2021 We sought to determine if manipulating resistance training (RT) variables differentially altered the expression of select sarcoplasmic and myofibril proteins as well as myofibrillar spacing in myofibers.
Carlton D. Fox +14 more
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