Results 11 to 20 of about 1,007,443 (313)

Bacterial nucleators: actin' on actin [PDF]

Pathogens and Disease, 2015
The actin cytoskeleton is a key target of numerous microbial pathogens, including protozoa, fungi, bacteria and viruses. In particular, bacterial pathogens produce and deliver virulence effector proteins that hijack actin dynamics to enable bacterial invasion of host cells, allow movement within the host cytosol, facilitate intercellular spread or ...
Joana N, Bugalhão, Luís Jaime, Mota, Irina S, Franco   +2 more
openaire   +2 more sources

Actin, actin-binding proteins, and actin-related proteins in the nucleus [PDF]

Histochemistry and Cell Biology, 2016
Extensive research in the past decade has significantly broadened our view about the role actin plays in the life of the cell and added novel aspects to actin research. One of these new aspects is the discovery of the existence of nuclear actin which became evident only recently.
Kristó, Ildikó, Bajusz, Izabella, Bajusz, Csaba, Borkúti, Péter, Vilmos, Péter   +4 more
openaire   +3 more sources

SUMOylation of nuclear actin [PDF]

, 2009
Actin, a major component of the cytoplasm, is also abundant in the nucleus. Nuclear actin is involved in a variety of nuclear processes including transcription, chromatin remodeling, and intranuclear transport.
Alessandro Arduini, Lessard, James L., Arduini, Alessandro, Nicol, Samantha M., Fuller-Pace, Frances V., Primal de Lanerolle, Samantha M. Nicol, Frances V. Fuller-Pace, Carlos J. Camacho, James L. Lessard, de Lanerolle, Primal, Wilma A. Hofmann, Camacho, Carlos J., Hofmann, Wilma A.   +13 more
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Viscoelastic response of cells and the role of actin cytoskeletal remodelling. [PDF]

, 2012
PhDThe mechanical properties of living cells provide useful information on cellular structure and function. In the present study a micropipette aspiration technique was developed to investigate the viscoelastic parameters of isolated articular ...
Pravincumar, Priyanka
core   +4 more sources

Wnt5b integrates Fak1a to mediate gastrulation cell movements via Rac1 and Cdc42 [PDF]

Open Biology, 2020
Focal adhesion kinase (FAK) mediates vital cellular pathways during development. Despite its necessity, how FAK regulates and integrates with other signals during early embryogenesis remains poorly understood.
I-Chen Hung, Tsung-Ming Chen, Jing-Ping Lin, Yu-Ling Tai, Tang-Long Shen, Shyh-Jye Lee   +5 more
doaj   +1 more source

Identification of the Antifungal Metabolite Chaetoglobosin P From Discosia rubi Using a Cryptococcus neoformans Inhibition Assay: Insights Into Mode of Action and Biosynthesis

Frontiers in Microbiology, 2020
Cryptococcus neoformans is an important human pathogen with limited options for treatments. We have interrogated extracts from fungal fermentations to find Cryptococcus-inhibiting natural products using assays for growth inhibition, differential ...
Bruno Perlatti, Connie B. Nichols, Nan Lan, Philipp Wiemann, Colin J. B. Harvey, J. Andrew Alspaugh, Gerald F. Bills   +6 more
doaj   +1 more source

Interactions between β-arrestin proteins and the cytoskeletal system, and their relevance to neurodegenerative disorders

Frontiers in Endocrinology, 2023
β-arrestins, which have multiple cellular functions, were initially described as proteins that desensitize rhodopsin and other G protein-coupled receptors.
Tibor Szénási, Gábor Turu, Gábor Turu, László Hunyady, László Hunyady   +4 more
doaj   +1 more source

Formins Determine the Functional Properties of Actin Filaments in Yeast [PDF]

, 2014
The actin cytoskeleton executes a broad range of essential functions within a living cell. The dynamic nature of the actin polymer is modulated to facilitate specific cellular processes at discrete locations by actin-binding proteins (ABPs), including ...
Mulvihill, Daniel P., East, Daniel A., Johnson, Matthew   +2 more
core   +1 more source

Mechanics and regulation of cytokinetic abscission

Frontiers in Cell and Developmental Biology, 2022
Cytokinetic abscission leads to the physical cut of the intercellular bridge (ICB) connecting the daughter cells and concludes cell division. In different animal cells, it is well established that the ESCRT-III machinery is responsible for the ...
Virginia Andrade, Virginia Andrade, Arnaud Echard   +2 more
doaj   +1 more source

Repetitive N-WASP–binding elements of the Enterohemorrhagic Escherichia coli Effector EspFU Synergistically Activate Actin Assembly [PDF]

, 2008
Enterohemorrhagic Escherichia coli (EHEC) generate F-actin–rich adhesion pedestals by delivering effector proteins into mammalian cells. These effectors include the translocated receptor Tir, along with EspFU, a protein that associates indirectly with ...
McGhie, E.J., Rosen, M.K., Kenneth G Campellone, Robbins, D., Cheng, HC, Robbins, D, Rosen, MK, Koronakis, V, John M Leong, Siripala, AD, Michael K Rosen, Koronakis, V., McGhie Emma J., Leong, JM, Hayward Richard D., Welch, MD, Campellone Kenneth G., Robbins Douglas, Campellone, K.G., Anosha D Siripala, Cheng, H.-C., Leong, J.M., Leong John M., Hui-Chun Cheng, Emma J McGhie, Cheng Hui-Chun, Hayward, RD, Richard D Hayward, Siripala Anosha D., Welch, M.D., Siripala, A.D., Hayward, Richard D., Douglas Robbins, Vassilis Koronakis, Galán, J.E., Campellone, KG, McGhie, EJ, Matthew D Welch, Rosen Michael K., Koronakis Vassilis, Welch Matthew D., Cheng, Hui-Chun, Robbins, Douglas, Siripala, Anosha D., Koronakis, Vassilis, Campellone, Kenneth Geno, Welch, Matthew D., McGhie, Emma J., Rosen, Michael K., Leong, John M.   +49 more
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