Results 11 to 20 of about 833,496 (268)
Bacterial nucleators: actin' on actin [PDF]
Pathogens and Disease, 2015 The actin cytoskeleton is a key target of numerous microbial pathogens, including protozoa, fungi, bacteria and viruses. In particular, bacterial pathogens produce and deliver virulence effector proteins that hijack actin dynamics to enable bacterial invasion of host cells, allow movement within the host cytosol, facilitate intercellular spread or ...
Joana N, Bugalhão +2 more
openaire +2 more sources
Actin, actin-binding proteins, and actin-related proteins in the nucleus [PDF]
Histochemistry and Cell Biology, 2016 Extensive research in the past decade has significantly broadened our view about the role actin plays in the life of the cell and added novel aspects to actin research. One of these new aspects is the discovery of the existence of nuclear actin which became evident only recently.
Kristó, Ildikó +4 more
openaire +3 more sources
Wnt5b integrates Fak1a to mediate gastrulation cell movements via Rac1 and Cdc42 [PDF]
Open Biology, 2020 Focal adhesion kinase (FAK) mediates vital cellular pathways during development. Despite its necessity, how FAK regulates and integrates with other signals during early embryogenesis remains poorly understood.
I-Chen Hung +5 more
doaj +1 more source
Frontiers in Microbiology, 2020 Cryptococcus neoformans is an important human pathogen with limited options for treatments. We have interrogated extracts from fungal fermentations to find Cryptococcus-inhibiting natural products using assays for growth inhibition, differential ...
Bruno Perlatti +6 more
doaj +1 more source
Frontiers in Endocrinology, 2023 β-arrestins, which have multiple cellular functions, were initially described as proteins that desensitize rhodopsin and other G protein-coupled receptors.
Tibor Szénási +4 more
doaj +1 more source
Mechanics and regulation of cytokinetic abscission
Frontiers in Cell and Developmental Biology, 2022 Cytokinetic abscission leads to the physical cut of the intercellular bridge (ICB) connecting the daughter cells and concludes cell division. In different animal cells, it is well established that the ESCRT-III machinery is responsible for the ...
Virginia Andrade +2 more
doaj +1 more source
Actin Remodeling Defects Leading to Autoinflammation and Immune Dysregulation
Frontiers in Immunology, 2021 A growing number of monogenic immune-mediated diseases have been related to genes involved in pathways of actin cytoskeleton remodeling. Increasing evidences associate cytoskeleton defects to autoinflammatory diseases and primary immunodeficiencies.
Riccardo Papa +3 more
doaj +1 more source
Actin and Actin-Binding Proteins [PDF]
Cold Spring Harbor Perspectives in Biology, 2016 Organisms from all domains of life depend on filaments of the protein actin to provide structure and to support internal movements. Many eukaryotic cells use forces produced by actin polymerization for their motility, and myosin motor proteins use ATP hydrolysis to produce force on actin filaments.
openaire +2 more sources
Journal of Lipid Research, 2002 Class A macrophage scavenger receptors (SR-A) are multifunctional receptors with roles in modified lipoprotein uptake, innate immunity, and macrophage adhesion.
Steven R. Post +5 more
doaj +1 more source
Frontiers in Molecular Biosciences, 2020 Depending on the physical and biochemical properties of actin-binding proteins, actin networks form different types of membrane protrusions at the cell periphery.
Yashar Bashirzadeh +5 more
doaj +1 more source