Results 21 to 30 of about 1,291,235 (309)

Frequent Manipulation of Resistance Training Variables Promotes Myofibrillar Spacing Changes in Resistance-Trained Individuals

Frontiers in Physiology, 2021
We sought to determine if manipulating resistance training (RT) variables differentially altered the expression of select sarcoplasmic and myofibril proteins as well as myofibrillar spacing in myofibers.
Carlton D. Fox, Paulo H. C. Mesquita, Joshua S. Godwin, Vitor Angleri, Felipe Damas, Bradley A. Ruple, Casey L. Sexton, Michael D. Brown, Andreas N. Kavazis, Kaelin C. Young, Kaelin C. Young, Carlos Ugrinowitsch, Cleiton A. Libardi, Michael D. Roberts, Michael D. Roberts   +14 more
doaj   +1 more source

Tobacco WLIM1 is a novel F-actin binding protein involved in actin cytoskeleton remodeling [PDF]

, 2006
We used confocal microscopy and in vitro analyses to show that Nicotiana tabacum WLIM1, a LIM domain protein related to animal Cys-rich proteins, is a novel actin binding protein in plants.
Thomas, Clément, Hoffmann, Céline, Dieterle, Monika, Van Troys, Marleen, Ampe, Christophe, Steinmetz, André   +5 more
core   +2 more sources

Wnt5b integrates Fak1a to mediate gastrulation cell movements via Rac1 and Cdc42 [PDF]

Open Biology, 2020
Focal adhesion kinase (FAK) mediates vital cellular pathways during development. Despite its necessity, how FAK regulates and integrates with other signals during early embryogenesis remains poorly understood.
I-Chen Hung, Tsung-Ming Chen, Jing-Ping Lin, Yu-Ling Tai, Tang-Long Shen, Shyh-Jye Lee   +5 more
doaj   +1 more source

Catastrophic disassembly of actin filaments via Mical-mediated oxidation. [PDF]

, 2017
Actin filament assembly and disassembly are vital for cell functions. MICAL Redox enzymes are important post-translational effectors of actin that stereo-specifically oxidize actin's M44 and M47 residues to induce cellular F-actin disassembly.
Ge, Peng, Grintsevich, Elena E, Reisler, Emil, Sawaya, Michael R, Terman, Jonathan R, Yesilyurt, Hunkar Gizem, Zhou, Z Hong   +6 more
core   +3 more sources

Identification of the Antifungal Metabolite Chaetoglobosin P From Discosia rubi Using a Cryptococcus neoformans Inhibition Assay: Insights Into Mode of Action and Biosynthesis

Frontiers in Microbiology, 2020
Cryptococcus neoformans is an important human pathogen with limited options for treatments. We have interrogated extracts from fungal fermentations to find Cryptococcus-inhibiting natural products using assays for growth inhibition, differential ...
Bruno Perlatti, Connie B. Nichols, Nan Lan, Philipp Wiemann, Colin J. B. Harvey, J. Andrew Alspaugh, Gerald F. Bills   +6 more
doaj   +1 more source

Interactions between β-arrestin proteins and the cytoskeletal system, and their relevance to neurodegenerative disorders

Frontiers in Endocrinology, 2023
β-arrestins, which have multiple cellular functions, were initially described as proteins that desensitize rhodopsin and other G protein-coupled receptors.
Tibor Szénási, Gábor Turu, Gábor Turu, László Hunyady, László Hunyady   +4 more
doaj   +1 more source

Mechanics and regulation of cytokinetic abscission

Frontiers in Cell and Developmental Biology, 2022
Cytokinetic abscission leads to the physical cut of the intercellular bridge (ICB) connecting the daughter cells and concludes cell division. In different animal cells, it is well established that the ESCRT-III machinery is responsible for the ...
Virginia Andrade, Virginia Andrade, Arnaud Echard   +2 more
doaj   +1 more source

The formin FHOD1 and the small GTPase Rac1 promote vaccinia virus actin-based motility [PDF]

, 2013
Vaccinia virus dissemination relies on the N-WASP– ARP2/3 pathway, which mediates actin tail formation underneath cell-associated extracellular viruses (CEVs).
Alberts, Alvarez, Arakawa, Bagrodia, Bernardini, Block, Boujemaa-Paterski, Chong, Chong, Diego E. Alvarez, Earl, Engelstad, Feig, Frischknecht, Fukuoka, Gasteier, Goldberg, Haglund, Hannemann, Harris, Harris, Heindl, Hervé Agaisse, Hiller, Hollinshead, Hoppe, Humphries, Isaacs, Katz, Kleba, Koka, Kovar, Krall, Lammers, Lasa, Li, Madrid, Moseley, Moseley, Newsome, Newsome, Nezami, Otomo, Parkinson, Pollard, Pring, Pruyne, Qiu, Ridley, Rietdorf, Roberts, Rolls, Romero, Röttger, Sanderson, Scaplehorn, Schmelz, Schulte, Schönichen, Schönichen, Serio, Shibata, Siripala, Skoble, Smith, Suzuki, Takeya, Tooze, van Eijl, van Eijl, Wallar, Ward, Ward, Watanabe, Weisswange, Welch, Westendorf, Westendorf, Wolffe, Wolffe   +79 more
core   +2 more sources

Actin Remodeling Defects Leading to Autoinflammation and Immune Dysregulation

Frontiers in Immunology, 2021
A growing number of monogenic immune-mediated diseases have been related to genes involved in pathways of actin cytoskeleton remodeling. Increasing evidences associate cytoskeleton defects to autoinflammatory diseases and primary immunodeficiencies.
Riccardo Papa, Federica Penco, Stefano Volpi, Marco Gattorno   +3 more
doaj   +1 more source

A pharmacological cocktail for arresting actin dynamics in living cells. [PDF]

, 2011
The actin cytoskeleton is regulated by factors that influence polymer assembly, disassembly, and network rearrangement. Drugs that inhibit these events have been used to test the role of actin dynamics in a wide range of cellular processes.
Peng, Grace E, Weiner, Orion D, Wilson, Sarah R   +2 more
core   +2 more sources