Results 171 to 180 of about 1,019,729 (309)

The class VIII myosin ATM2 stabilizes actin-plasma membrane contacts in tobacco pollen tubes by locally promoting PtdIns(4,5)P₂ formation. [PDF]

Nat Plants
Wagner VC, Fratini M, Uhlenberg J, Schutkowski A, Hamm G, Kastner C, Bacia K, Schwarzerová K, Heilmann I.   +8 more
europepmc   +1 more source

Microgels Enable iPSCs to Assemble, Expand, and Differentiate Into Organoids—From Sizable to High‐Throughput

Advanced Materials, EarlyView.
A chemically defined PEG‐based microgel platform enables scalable, reproducible production of three‐dimensional microgel‐iPSC constructs in multiple sizes. The system is compatible with high‐throughput automation and supports human iPSC expansion and differentiation within a single construct, including directed differentiation into cardiac organoids ...
Laura Klasen, Matthias Mork, Ramin Nasehi, Vasudha Turuvekere Krishnamurthy, Kira Zeevaert, Aaron Babendreyer, Jacopo Di Russo, Wolfgang Wagner, Laura De Laporte   +8 more
wiley   +1 more source

Septins buffer actomyosin forces to protect the nucleus from genotoxic mechanical stress. [PDF]

J Cell Biol
Mayca Pozo F, Butts SM, Schaefer AW, Montagna C, Spiliotis ET.   +4 more
europepmc   +1 more source

Fabrication of Aligned Polycaprolactone Nanofibrillar Bundles to Control Cell‐Mediated Collagen Deposition in Engineered Cartilage

Advanced Materials, EarlyView.
Melt electrofibrillation (MEF) enables the fabrication of nanofibrillar PCL scaffolds with defined architectures that guide cellular alignment and retention during cartilage tissue engineering. Unlike conventional melt electrowriting, MEF consistently directs collagen type II‐rich extracellular matrix organization, providing a tunable platform to ...
Alba Pueyo Moliner, Lennard Spauwen, James L. Martin Robinson, Ángela García Grech, Isabelle Martinier, Sara Grasselli, Aylin Kara Özenler, Matthias Ryma, Jürgen Groll, Mylène de Ruijter, Jos Malda   +10 more
wiley   +1 more source

Bacteria‐Trained, MnO2‐Armored Dendritic Cells for Immunotherapy

Advanced Materials, EarlyView.
MnO2‐armored, bacteria‐trained dendritic cells undergo tumor‐responsive mechanical and immunological transformation. The nanocoating masks immune ligands and maintains a mechanically stiff, quiescent state during circulation, while the tumor microenvironment removes the armor and restores cellular deformability and immune accessibility.
Zhao Guo, Min Ge, Zesong Ruan, Tingwang Shi, Mahyar Mahmoudi, Soohwan An, Na Kong, Yunfeng Chen, Han Lin, Wei Tao   +9 more
wiley   +1 more source

CAP1/CAP2 at the Actin Filament Barbed End: Reconciling Kinetic, Single-Molecule, Structural and Cellular Evidence. [PDF]

Cells
Ngo THP, Lee W.
europepmc   +1 more source

Mechanoactive Biomaterials for Cell–Matrix Mechanotransduction

Advanced Materials, EarlyView.
The graphical abstract shows how individual triggers (force, light, or temperature) and combined optothermal or receptor‐targeted actuation induce material responses at the tissue, cellular, and receptor scales. Their spatial (global or focused) and temporal (continuous or cyclic) modulation determines the resulting mechanical output.
Yi‐Tung Lu, Alison E. John, Marc A. Fernández‐Yagüe   +2 more
wiley   +1 more source

Kenneth Charles Holmes 1934–2021

Frontiers in Molecular Biosciences, 2022
Belinda Bullard
doaj   +1 more source

Vitamin C‐Induced Photo‐Redox Threshold Enables High‐Fidelity Volumetric Printing of Collagen

Advanced Materials, EarlyView.
Tomographic volumetric printing (TVP) of native proteins is limited by uncontrolled background crosslinking. Here, vitamin C is introduced as a biocompatible redox regulator to establish a tunable nonlinear polymerization threshold response for TVP.
Bin Wang, Amelia Hasenauer, Kristian Ivkovic, Ann‐Sophie Frind, David Fercher, Marcy Zenobi‐Wong   +5 more
wiley   +1 more source

Mycobacterial Lipids Orchestrate Infection Stage-Specific Remodeling of the Host Actin Cytoskeleton. [PDF]

ACS Omega
Mishra M, Roy SL, Dasgupta A, Menon AP, Kapoor S.   +4 more
europepmc   +1 more source