Results 181 to 190 of about 1,007,443 (313)

From Fiber Bundles to Architected Membranes: Triply Periodic Minimal Surface Architectures for Biohybrid Artificial Lungs

Advanced Materials, EarlyView.
Additively manufactured triply periodic minimal surface (TPMS) membranes offer an architecture‐driven alternative to hollow fiber bundles in artificial lungs. Multiphysics simulations and endothelialized prototypes show that the 3D‐printable membrane architecture improves gas exchange, blood flow distribution, and hemocompatibility, enabling ...
Michael Pflaum, Kai P. Barbian, Florian Neuhaus, Gerrit Sitarz, Carolin Nölke, Sebastian V. Jansen, John Linkhorst, Lukas T. Hirschwald, Sebastian Brosch, Christian Certa, Ulrich Steinseifer, Matthias Wessling, Jutta Arens, Arjang Ruhparwar, Bettina Wiegmann   +14 more
wiley   +1 more source

α-Parvin regulation of cell rearrangement is critical for ureteric bud branching morphogenesis. [PDF]

Sci Adv
Dong X, Bock F, Hashmi A, Bulus N, Mernaugh G, Bolas G, Li S, Zhu W, Melzer M, Brown K, Miller C, Viquéz O, Montañez E, Pozzi A, Wickström SA, Zent R.   +15 more
europepmc   +1 more source

Transient Cytoskeletal Anisotropy Encodes Short‐Term Mechanical Memory in Glioblastoma Cells

Advanced Materials, EarlyView.
The same mechanical deformation can produce distinct cytoskeletal states depending on loading history. Experiments and constitutive modeling reveal that transient actin–vimentin anisotropy stores mechanical information and governs short‐term mechanical memory in glioblastoma cells.
Clara Gomez‐Cruz, Matthieu Gelin, Lucas Pradeau‐Phélut, Arrate Muñoz‐Barrutia, Sandrine Etienne‐Manneville, Daniel Garcia‐Gonzalez   +5 more
wiley   +1 more source

The Role of Arp2/3 in End-Resection During DNA Double-Strand Break Repair. [PDF]

Bioessays
Zhou FY, Haber JE.
europepmc   +1 more source

Engineering Pluripotent Stem Cells‐Derived Inner Ear Organoids With Enhanced Maturation and Reproducibility by Micro‐Topographical Cues

Advanced Materials, EarlyView.
Micro‐topographical cues applied through temporally controlled microscale confinement improve the reproducibility, spatial organization, and neurosensory‐associated features of pluripotent stem cell‐derived inner ear organoids. Integration with a vascularized organoid platform further enables controlled investigation of vascular‐epithelial interactions
Harshita Sharma, Jungeun Lim, Woochan Kim, Yeon Ju Kim, Dream Kim, Shinyull Lee, Chaeyeon Park, Stephen Rhee, Shruthy Kuttapan, Jungho Ha, Sang Wook Park, Kyunghoon Kim, Noo Li Jeon, Sunho Park, Yun‐Hoon Choung, Jangho Kim   +15 more
wiley   +1 more source

Dosage-sensitive regulation of Cofilin-1 and LIMK signaling controls myoblast differentiation and fusion. [PDF]

Cell Mol Life Sci
Gjirlić D, Weber A, Posern G, Singh AK.
europepmc   +1 more source

Elastomeric 3D‐Printed Microenvironments Enable Nanonewton Force Measurements in Healthy and Diseased Human Pluripotent Stem Cell‐Derived Neuroepithelial Cells

Advanced Materials, EarlyView.
We present elastomeric three‐dimensional (3D) microstructures fabricated via two‐photon polymerization (2PP) and post‐processed through wet etching, for quantifying nanonewton (nN)‐scale forces applied by healthy and diseased neural cells. The mechanically characterized free‐standing beam architectures enable measurement of traction forces of ...
Pieter F. J. van Altena, Lucia Castillo Ransanz, Ruben H. Guis, Giulia Bergamaschi, Nanne J. Paauw, Urs Staufer, Vivi M. Heine, Angelo Accardo   +7 more
wiley   +1 more source

<i>Legionella</i> effector RavH is a tandem WH2-like domain-containing PI(3)P-dependent actin nucleator. [PDF]

Life Sci Alliance
Zhang Q, Kudryashova E, Sanford E, Wagner MM, Minelli ME, Smolka MB, Kudryashov DS, Mao Y.   +7 more
europepmc   +1 more source

S‐Nitrosothiols as Thiol‐Protecting Groups for Controlled Thiol‐Maleimide Crosslinking of Homogeneous Soft Hydrogels

Advanced Materials, EarlyView.
Rapid thiol‐maleimide addition frequently outpaces mixing, resulting in heterogeneous hydrogels. S‐nitrosothiols act as thiol‐protecting groups, allowing uniform mixing with maleimide‐functionalized polymers before gelation. Sodium thiosulfate or sodium ascorbate then regenerates thiols on demand, triggering controlled thiol‐maleimide crosslinking ...
Julian A. Serna, Michelle J. Iwohn, Maximilian Seifermann, Stefan Heißler, Maike Schliephake, Franziska Dopp, Claudia Muhle‐Goll, Pavel A. Levkin   +7 more
wiley   +1 more source

Form and function of actin impacts actin health and aging. [PDF]

iScience
Averbukh M, Nelson HT, Wang T, Lange CM, Alcala A, Kim J, Suh D, Vega M, Gao SM, Dutta N, Young KE, Aviles Barahona R, Coakley AJ, Gerke JA, Odron SF, Clarke JG, Singh N, Nickel MS, Peterson JC, Lam-Truong HL, Moaddeli D, Castro Torres T, Oorloff M, Peruch M, Nair T, Mehta HH, Thorwald MA, Ono S, Curran SP, Wang MC, Benayoun BA, Hill CM, Johnson TA, Crimmins EM, Arpawong TE, Kumsta C, Garcia G, Higuchi-Sanabria R.   +37 more
europepmc   +1 more source