Results 201 to 210 of about 815,791 (269)

Structural basis for BCL7B-mediated ncBAF-nucleosome engagement. [PDF]

Nucleic Acids Res
Sun F, Zou B, Li H, Xu C, Luo Q, Wang C, Xu P, Pei D, Chen J, Qin D, Zhang Y, He J.   +11 more
europepmc   +1 more source

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

Advanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim, Ye‐Ji Kim, Seyoung Ryu, Daeui Park, Kyoung‐Sik Moon, Yu Bin Lee, Dong Ho Woo   +6 more
wiley   +1 more source

Camsap2a regulates actomyosin flow and Rab5ab-mediated macropinocytosis in the yolk cell during zebrafish epiboly. [PDF]

Development
Wan H, Quibria S, Iu E, User SD, Plotnikov SV, Bruce AEE.   +5 more
europepmc   +1 more source

Human Brain Vasculature‐on‐a‐Chip Model Constructed With Microvessels Isolated From Cryopreserved Postmortem Human Brain Tissue

Advanced Healthcare Materials, EarlyView.
This manuscript describes the cultivation of viable microvessels from cryopreserved human brain tissue. When embedded in hydrogels and cultured in microfluidic devices, these microvessels exhibit complex architectures reminiscent of arterioles and capillaries, can be perfused, and display intact barrier function. Collectively, these results demonstrate
Brian J. O'Grady, A. Scott McCall, Samuel Cullison, Daniel Chavarria, Matthew S. Schrag, Ethan S. Lippmann   +5 more
wiley   +1 more source

Amyloid Beta Oligomers as Early Triggers of Neuronal Cytoskeleton Dysfunction in Alzheimer's Disease. [PDF]

Pathophysiology
Gasca-Martínez Y, Ontiveros-Torres MA, López-Gallegos I, Jarero-Basulto JJ.   +3 more
europepmc   +1 more source

Interfacial Bioengineering of Dynamic Networks Hybrid Hydrogel for Programmed Intervention in Oral Precancerous Epithelial States

Advanced Healthcare Materials, EarlyView.
This study develops a dual‐bioinspired hydrogel, MSA@PGel (macrophage membrane‐coated and salvianolic acid B/5‐aminolevulinic acid co‐loaded liposomes embedded in a polydopamine‐based gel), that integrates macrophage membrane‐mediated active targeting and mussel‐inspired wet adhesion for programmed intervention in oral precancerous lesions.
Xiaoxian Zhao, Ao Zheng, Zhengyan Zhao, Qilin Li, Tianhao Wan, Tanjun Deng, Ying Zhang, Lingyan Cao, Lan Wu   +8 more
wiley   +1 more source

MYH9 mutations differentially stabilize non-muscle myosin II filaments and induce distinct cellular aggregation phenotypes. [PDF]

Cell Mol Life Sci
Llorente-González C, Mustafina K, Asensio-Juárez G, Garrido-Casado M, Talayero VC, Pérez-Díaz R, Ramos-Solano H, Sellers JR, Chinthalapudi K, Wiseman PW, Heissler SM, Vicente-Manzanares M.   +11 more
europepmc   +1 more source

A revised model of nuclear actin import: Importin 9 competes with cofilin, profilin, and RanGTP for actin binding. [PDF]

J Biol Chem
Keplinger AJ, Srinivasan PA, Christensen SM, Suarez C, Ruthenburg AJ.   +4 more
europepmc   +1 more source

Roles of cytoskeleton in metastasis: from its mechanism to therapeutic strategies. [PDF]

Exp Mol Med
Lim S, Woo S, Lee KW, Kim KD.
europepmc   +1 more source

Retraction: Mitostatin is down-regulated in human prostate cancer and suppresses the invasive phenotype of prostate cancer cells. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source