Genome-wide association mapping and targeted loss of function studies identify <i>Shroom3</i> as a driver of hyperpolyploidy and ventricular dilation. [PDF]
Purdy AL +18 more
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Experimental Validation and Bioinformatics Analysis Elucidate the Role of MTDH-Mediated PTEN Ubiquitination and Degradation in Podocyte Injury in Diabetic Kidney Disease. [PDF]
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RETRACTION: Spliceosomal Protein E Regulates Neoplastic Cell Growth by Modulating Expression of Cyclin E/CDK2 and G2/M Checkpoint Proteins. [PDF]
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[Corrigendum] Inhibition of DNA‑PK activity sensitizes A549 cells to X‑ray irradiation by inducing the ATM‑dependent DNA damage response. [PDF]
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Plasmodium motility: actin not actin' like actin
Trends in Parasitology, 2006Apicomplexan parasites such as Plasmodium and Toxoplasma display actomyosin-dependent motility in the absence of readily detectable actin polymers. Three recent studies indicate that parasite actin polymers, either harvested from parasites or formed from purified recombinant proteins, are exceptionally short ( approximately 100 nm).
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Studies on actin-actin and actin-myosin interaction
Biochimica et Biophysica Acta (BBA) - Protein Structure, 1967Abstract 1. 1.|The reagents hydrogen peroxide, iodine and 1,5-difluoro-2,4-dinitrobenzene did not affect the bound nucleotide content of F-actin or G-actin at all when the viscosity of the actins and their ability to interact with myosin were greatly decreased. 2.
G, Bailin, M, Bárány
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Actin-actin binding protein interfaces
Seminars in Cell Biology, 1994The recent elucidation of the three-dimensional structure of gelsolin segment 1 and profilin provides new insights on how these proteins recognize actin. Although the picture is still incomplete and not all biochemical data are consolidated, the results offer clues on how these proteins exert their effect on actin and how they may modulate the ...
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