Results 91 to 100 of about 287,702 (305)

Actin automata with memory [PDF]

open access: yes, 2016
Actin is a globular protein which forms long polar filaments in eukaryotic. The actin filaments play roles of cytoskeleton, motility units , information processing and learning. We model actin filament as a double chain of finite state machines, nodes, which take states `0' and `1'. The states are abstractions of absence and presence of a sub-threshold
arxiv   +1 more source

The actin cytoskeleton in presynaptic assembly [PDF]

open access: yesCell Adhesion & Migration, 2013
Dramatic morphogenetic processes underpin nearly every step of nervous system development, from initial neuronal migration and axon guidance to synaptogenesis. Underlying this morphogenesis are dynamic rearrangements of cytoskeletal architecture. Here we discuss the roles of the actin cytoskeleton in the development of presynaptic terminals, from the ...
Andrea K.H. Stavoe   +2 more
openaire   +3 more sources

High Rates of Actin Filament Turnover in Budding Yeast and Roles for Actin in Establishment and Maintenance of Cell Polarity Revealed Using the Actin Inhibitor Latrunculin-A [PDF]

open access: yes, 1997
We report that the actin assembly inhibitor latrunculin-A (LAT-A) causes complete disruption of the yeast actin cytoskeleton within 2–5 min, suggesting that although yeast are nonmotile, their actin filaments undergo rapid cycles of assembly and ...
Adams   +75 more
core   +4 more sources

Engineering the Hierarchical Porosity of Granular Hydrogel Scaffolds Using Porous Microgels to Improve Cell Recruitment and Tissue Integration

open access: yesAdvanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
By fabricating and covalently assembling gelatin methacryloyl (GelMA) porous microgels, a new class of granular hydrogel scaffolds with hierarchical porosity is developed. These scaffolds have a significantly higher void fraction than their counterparts made up of nonporous microgels, enhancing cell recruitment and tissue integration. This research may
Alexander Kedzierski   +9 more
wiley   +1 more source

Actin cytoskeleton regulates Hippo signaling. [PDF]

open access: yesPLoS ONE, 2013
Hippo pathway controls the organ size by modulating cell proliferation and apoptosis. However, the upstream regulation of hippo signaling by actin cytoskeleton is not clear.
Pradeep Reddy   +3 more
doaj   +1 more source

Microtubule-based actin transport and localization in a spherical cell [PDF]

open access: yesarXiv, 2020
The interaction between actin filaments and microtubules is crucial for many eukaryotic cellular processes, such as, among others, cell polarization, cell motility and cellular wound healing. The importance of this interaction has long been recognised, yet very little is understood about both the underlying mechanisms and the consequences for the ...
arxiv  

Mythical origins of the actin cytoskeleton

open access: yesCurrent Opinion in Cell Biology, 2021
The origin of the eukaryotic cell is one of the greatest mysteries in modern biology. Eukaryotic-wide specific biological processes arose in the lost ancestors of eukaryotes. These distinctive features, such as the actin cytoskeleton, define what it is to be a eukaryote.
Wipa Suginta   +9 more
openaire   +4 more sources

Bacterial toxins modifying the actin cytoskeleton [PDF]

open access: yes, 2010
Numerous bacterial toxins recognize the actin cytoskeleton as a target. The clostridial binary toxins (Iota and C2 families) ADP-ribosylate the actin monomers causing the dissociation of the actin filaments.
Claude Bouchaud   +5 more
core   +2 more sources

PECAM-1 engagement counteracts ICAM-1-induced signaling in brain vascular endothelial cells [PDF]

open access: yes, 2007
Interactions between leukocytes and vascular endothelial cells are mediated by a complex set of membrane adhesion molecules which transduce bi-directional signals in both cell types.
Adamson   +53 more
core   +2 more sources

Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects

open access: yesAdvanced Functional Materials, EarlyView.
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu   +6 more
wiley   +1 more source

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