Results 121 to 130 of about 287,702 (305)

Wdpcp, a PCP Protein Required for Ciliogenesis, Regulates Directional Cell Migration and Cell Polarity by Direct Modulation of the Actin Cytoskeleton [PDF]

, 2013
Planar cell polarity (PCP) regulates cell alignment required for collective cell movement during embryonic development. This requires PCP/PCP effector proteins, some of which also play essential roles in ciliogenesis, highlighting the long-standing ...
Adam V. Kwiatkowski, AJ Ross, B Schermer, Bishwanath Chatterjee, C Cui, C Jones, C Jones, C Stuckenholz, CB Kimmel, CD Nobes, Cecilia W. Lo, Chandrakala Puligilla, Cheng Cui, CJ Haycraft, CU Stirnimann, CW Sipe, D Huangfu, D Huangfu, D Yelon, Deanne Francis, E Joo, EK Vladar, Elias T. Spiliotis, F Hildebrandt, GJ Pazour, Gregory J. Pazour, Hisato Yagi, HM Phillips, HM Phillips, I Drummond, J Magdalena, J Wang, J Wang, JB Wallingford, JB Wallingford, JL Badano, Jovenal T. San Agustin, K Schmidt, K Takemaru, KC Corbit, KC Corbit, Lisa M. Swanhart, M Castori, M Fliegauf, M Kelly, M Kinoshita, M Montcouquiol, M Simons, Matthew P. Scott, Matthew W. Kelley, Neil A. Hukriede, Q Hu, Q Yu, Qing Yu, R Rohatgi, RA Meseroll, Richard J. Francis, RJ Francis, Rocky Tuan, S Collier, S Maretto, S Saburi, SD Weatherbee, SK Kim, Subramaniam Sanker, T Caspary, T Kudoh, Tania Chatterjee, Terry Tansey, Thomas P. Lozito, TJ Park, X Wen, Xiaoqin Liu, Y Wang, Zhen Zhang   +74 more
core   +4 more sources

Engineering Assembloids to Mimic Graft‐Host Skeletal Muscle Interaction

Advanced Healthcare Materials, EarlyView.
This study develops a graft‐host skeletal muscle assembloid model combining neuromuscular organoids with tissue‐engineered constructs. Pre‐seeding decellularized muscles with myogenic cells enhances cell migration and axon invasion from the organoid. The model exhibits regenerative capacity following acute damage, advancing the understanding of human ...
Lucia Rossi, Beatrice Auletta, Luigi Sartore, Marco La Placa, Giada Cecconi, Pietro Chiolerio, Edoardo Maghin, Silvia Angiolillo, Eugenia Carraro, Onelia Gagliano, Cecilia Laterza, Nicola Elvassore, Martina Piccoli, Anna Urciuolo   +13 more
wiley   +1 more source

Kinetics of actin networks formation measured by time resolved particle-tracking microrheology [PDF]

arXiv, 2020
Actin is one of the most studied cytoskeleton proteins showing a very rich span of structures. It can self-assemble actively into dynamical structures that govern the mechanical properties of the cell, its motility and its division. However, only very few studies characterize the kinetics of the active actin self-assembly process beyond the formation ...
arxiv  

HCMV pUL135 remodels the actin cytoskeleton to impair immune recognition of infected cells [PDF]

, 2014
Immune evasion genes help human cytomegalovirus (HCMV) establish lifelong persistence. Without immune pressure, laboratory-adapted HCMV strains have undergone genetic alterations.
Aicheler, Andrew J. Davison, Arnon, Benedict, Bentz, Billadeau, Borivoj Vojtesek, Brown, Butler, Cerboni, Chapman, Dargan, Davis, Eddie C.Y. Wang, Evans, Fielding, Gavin S. Wilkie, Gavin W.G. Wilkinson, Gross, Humphries, Jürgen Haas, Kelly L. Miners, Kim, Le, Mace, Marco A. Purbhoo, Marcus Heinzmann, Melanie Moore, Michael P. Weekes, Morris, Orange, Paul J. Lehner, Penfold, Peter Tomasec, Prod’homme, Prod’homme, Prod’homme, Rak, Rebecca J. Aicheler, Richard J. Stanton, Riedl, Robin Antrobus, Ryu, Seo, Smith, Stanton, Stanton, Stanton, Stephen Man, Striebinger, Susanne M. Bailer, Takenawa, Tani, Taylor, Tomasec, Tomasec, Umashankar, Virginie Prod’homme, Wang, Weekes, Wilkinson   +60 more
core   +3 more sources

Engineering the Future of Restorative Clinical Peripheral Nerve Surgery

Advanced Healthcare Materials, EarlyView.
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell, Zarina S. Ali, Eric L. Zager, Joseph M. Rosen, Mykhailo M. Tatarchuk, D. Kacy Cullen   +5 more
wiley   +1 more source

cis-acting sequences and trans-acting factors in the localization of mRNA for mitochondrial ribosomal proteins [PDF]

, 2008
mRNA localization is a conserved post-transcriptional process crucial for a variety of systems. Although several mechanisms have been identified, emerging evidence suggests that most transcripts reach the protein functional site by moving along ...
AMORESANO, ANGELA, C. Cirulli, PIETROPAOLO, CONCETTA, PUCCI, PIETRO, RUSSO, ANNAPINA, RUSSO, GIULIA   +5 more
core   +1 more source

Engineered 3D Kidney Glomerular Microtissues to Model Podocyte‐Centric Diseases for the Validation of New Drug Targets

Advanced Healthcare Materials, EarlyView.
The study introduces innovative 3D microtissues that replicate the glomerular filtration barrier of the kidney, offering a novel platform for understanding podocytopathies. These microtissues simulate the glomerulus's structure and dynamics, allowing for the modeling of podocyte injuries and drug testing.
Sara Buttό, Solange Vidal, Xi Rui Zeng, Martin Rausch, Immihan Ceren Yasa, Magali P. Ferro   +5 more
wiley   +1 more source

Fimbrin associated with Pmk1 to regulate the actin assembly during Magnaporthe oryzae hyphal growth and infection

Stress Biology
The dynamic assembly of the actin cytoskeleton is vital for Magnaporthe oryzae development and host infection. The actin-related protein MoFim1 is a key factor for organizing the M. oryzae actin cytoskeleton.
Yuan-Bao Li, Ningning Shen, Xianya Deng, Zixuan Liu, Shuai Zhu, Chengyu Liu, Dingzhong Tang, Li-Bo Han   +7 more
doaj   +1 more source

A Role for Exocytosis in the Spatial Regulationof Actin Organization

The Scientific World Journal, 2003
The efficient organization of the actin cytoskeleton is important for many cellular functions. However, how the local actin organization is regulated in a cell is not well understood.
Xiang-Dong Gao, Stefan Albert
doaj   +1 more source

Similarities and differences between the E5 oncoproteins of bovine papillomaviruses type 1 and type 4: Cytoskeleton, motility and invasiveness in E5-transformed bovine and mouse cells [PDF]

, 2006
Bovine papillomaviruses (BPVs) are oncogenic viruses. In cattle, BPV-1/2 is associated with urinary bladder cancer and BPV-4 with upper GI tract cancer. BPV E5 is a small hydrophobic protein localised in the endoplasmic reticulum (ER) and Golgi apparatus
Anderson, Araibi, Ashrafi, Ashrafi, Barbara Marchetti, Brad Ozanne, Burnett, Campo, Carragher, DiMaio, Emmanuella Tsirimonaki, Faccini, Fackler, Frame, Frame, Frame, Frame, G. Hossein Ashrafi, Geiger, Hennigan, Jackson, Jaggar, Jarrett, Kasper, Lu, Lynn McGarry, M. Saveria Campo, Marchetti, Nobes, Nunbhakdi-Craig, O’Brien, O’Brien, O’Brien, Pennie, Robina Ullah, Schapiro, Schiller, Scott, Suprynowicz, zur Hausen   +39 more
core   +1 more source