α-Cyclodextrin/Moringin Impacts Actin Cytoskeleton Dynamics with Potential Implications for Synaptic Organization: A Preliminary Transcriptomic Study in NSC-34 Motor Neurons. [PDF]
Gugliandolo A +7 more
europepmc +1 more source
Connexin 26 Functions as a Direct Transcriptional Regulator During the Cochlea Development
Connexin26 can not only form intercellular channels that mediate rapid communication on the cell membrane, but also enter the nucleus as a transcription factor to directly regulate the transcription of nuclear genes. In the developing cochlea, Cx26 can control the maturation of the molecular scissor ADAM10 by regulating the transcription of TspanC8 ...
Xiaozhou Liu +8 more
wiley +1 more source
The ER-PM interaction is essential for cytokinesis and recruits the actin cytoskeleton through the SCAR/WAVE complex. [PDF]
Xu Z +12 more
europepmc +1 more source
This study presents a two‐color FCCS and coincident‐burst analysis platform to quantify actin cargo in dual‐labeled EVs secreted from hiPSCs. The approach tracks secretion dynamics, confirms actin loading, and measures EV size and cargo number, offering insights into cytoskeletal disruption and neuronal differentiation relevant to neurodegenerative ...
Dang Du Nguyen +4 more
wiley +1 more source
ROS-Drp1-mitophagy feedback loop regulates myogenic differentiation via actin cytoskeleton remodeling-mediated MRTF-A/SRF axis. [PDF]
Jiang A +6 more
europepmc +1 more source
Material‐Induced Nuclear Deformation Controls Chromatin Architecture in Adipose Stem Cells
Tuning cell and cytoskeleton mechanics modulated nuclear shape and heterochromatin organization in ASCs. Distinct cytoskeletal architectures induced nuclear morphologies from oblate to prolate ellipsoids. Large elongated cells with a structured actin cap exhibited high nuclear strain, driving nuclear envelope deformation and heterochromatin ...
Carlo F. Natale +6 more
wiley +1 more source
Annexin A3 Represses Endothelial Permeability and Inflammation During Sepsis via Actin Cytoskeleton Modulation. [PDF]
Xing M, Liang S, Cao W, Guo Q, Zou W.
europepmc +1 more source
Active Force Dynamics in Red Blood Cells Under Non‐Invasive Optical Tweezers
A non‐invasive method combines low‐power optical tweezers with high‐speed microscopy to simultaneously monitor local membrane forces and displacements in single human red blood cells. This dual‐channel approach reveals a mechano‐dynamic signature that correlates the cell's metabolic state with its mechanical activity. This energetic framework serves as
Arnau Dorn +5 more
wiley +1 more source

