Results 11 to 20 of about 6,799 (175)
Functional insights into Plasmodium actin-depolymerizing factor interactions with phosphoinositides. [PDF]
J Biol ChemAbstract Malaria is caused by protozoan parasites, Plasmodium spp., that belong to the phylum Apicomplexa. The life cycle of these parasites depends on two different hosts; the definitive host, or vector, is a mosquito, and the intermediate host is a vertebrate, such as human ...
Lasiwa D, Kursula I.
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Actin filament remodeling by actin depolymerization factor/cofilin [PDF]
Proceedings of the National Academy of Sciences, 2010 We investigate, using molecular dynamics, how the severing protein, actin depolymerization factor (ADF)/cofilin, modulates the structure, conformational dynamics, and mechanical properties of actin filaments. The actin and cofilactin filament bending stiffness and corresponding persistence lengths obtained from all-atom simulations are comparable to ...
Jim, Pfaendtner +2 more
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Actin depolymerizing factor and the organization and distribution of actin in astrocytomas and meningiomas [PDF]
British Journal of Cancer, 1983 Actin depolymerizing factor and the organization and distribution of actin in astrocytomas and ...
Harmer, J. H. +5 more
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Structure of the actin-depolymerizing factor homology domain in complex with actin [PDF]
The Journal of Cell Biology, 2008 Actin dynamics provide the driving force for many cellular processes including motility and endocytosis. Among the central cytoskeletal regulators are actin-depolymerizing factor (ADF)/cofilin, which depolymerizes actin filaments, and twinfilin, which sequesters actin monomers and caps filament barbed ends.
Paavilainen, Ville O. +3 more
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APlasmodiumActin-depolymerizing Factor That Binds Exclusively to Actin Monomers [PDF]
Molecular Biology of the Cell, 2005 ADF/cofilins (AC) are essential F- and G-actin binding proteins that modulate microfilament turnover. The genome of Plasmodium falciparum, the parasite causing malaria, contains two members of the AC family. Interestingly, P. falciparum ADF1 lacks the F-actin binding residues of the AC consensus.
Herwig, Schüler +2 more
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Isolation and characterization of a regulated form of actin depolymerizing factor [PDF]
The Journal of cell biology, 1993 Actin depolymerizing factor (ADF) is an 18.5-kD protein with pH-dependent reciprocal F-actin binding and severing/depolymerizing activities. We previously showed developing muscle down-regulates ADF (J. R. Bamburg and D. Bray. 1987. J. Cell Biol. 105: 2817-2825).
T E, Morgan +4 more
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Crop Journal, 2022 Fiber productivity and quality of cotton are severely affected by abiotic stresses. In this study, we identified the role of GhADF1, an actin depolymerizing factor, in cotton response to drought stress.
Lixia Qin +6 more
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Coactosin Promotes F-Actin Protrusion in Growth Cones Under Cofilin-Related Signaling Pathway
Frontiers in Cell and Developmental Biology, 2021 During brain development, axon outgrowth and its subsequent pathfinding are reliant on a highly motile growth cone located at the tip of the axon. Actin polymerization that is regulated by actin-depolymerizing factors homology (ADF-H) domain-containing ...
Xubin Hou +5 more
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Stem Cell Research, 2015 Remodeling of the actin cytoskeleton through actin dynamics is involved in a number of biological processes, but its role in human stromal (skeletal) stem cells (hMSCs) differentiation is poorly understood.
Li Chen +6 more
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Actin depolymerization enhances adipogenic differentiation in human stromal stem cells
Stem Cell Research, 2018 Human stromal stem cells (hMSCs) differentiate into adipocytes that play a role in skeletal tissue homeostasis and whole body energy metabolism. During adipocyte differentiation, hMSCs exhibit significant changes in cell morphology suggesting changes in ...
Li Chen +4 more
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