Results 11 to 20 of about 45,871 (227)

Effect of SDS Micelles on Actinomycin D – DNA Complexes

Acta Chimica Slovenica, 2022
DNA thermal denaturation was evaluated as a measure of the effect of antitumor drug actinomycin D on the stability of the double helix and also the effect of SDS micelles on actinomycin D – DNA complexes.
Ana Maria Toader, Izabella Dascalu, Mirela Enache   +2 more
doaj   +1 more source

Molecular Details of Actinomycin D-Treated MRSA Revealed via High-Dimensional Data

Marine Drugs, 2022
Methicillin-resistant Staphylococcus aureus (MRSA) is highly concerning as a principal infection pathogen. The investigation of higher effective natural anti-MRSA agents from marine Streptomyces parvulus has led to the isolation of actinomycin D, that ...
Xuewei Xia, Jun Liu, Li Huang, Xiaoyong Zhang, Yunqin Deng, Fengming Li, Zhiyuan Liu, Riming Huang   +7 more
doaj   +1 more source

Identification and characterization of Streptomyces flavogriseus NJ-4 as a novel producer of actinomycin D and holomycin [PDF]

PeerJ, 2017
This paper is the first public report that Streptomyces flavogriseus can produce both actinomycin D and holomycin. The actinomycete strain NJ-4 isolated from the soil of Nanjing Agricultural University was identified as S. flavogriseus.
Zhaohui Wei, Chao Xu, Juan Wang, Fengxia Lu, Xiaomei Bie, Zhaoxin Lu   +5 more
doaj   +2 more sources

Isolation, characterization, anti-MRSA evaluation, and in-silico multi-target anti-microbial validations of actinomycin X2 and actinomycin D produced by novel Streptomyces smyrnaeus UKAQ_23

Scientific Reports, 2021
Streptomyces smyrnaeus UKAQ_23, isolated from the mangrove-sediment, collected from Jubail,Saudi Arabia, exhibited substantial antimicrobial activity against methicillin-resistant Staphylococcus aureus (MRSA), including non-MRSA Gram-positive test ...
Kamal A. Qureshi, Avinash D. Bholay, Pankaj K. Rai, Hamdoon A. Mohammed, Riaz A. Khan, Faizul Azam, Mariusz Jaremko, Abdul-Hamid Emwas, Piotr Stefanowicz, Mateusz Waliczek, Monika Kijewska, Ehab A. Ragab, Medhat Rehan, Gamal O. Elhassan, Md Jamir Anwar, Dinesh K. Prajapati   +15 more
doaj   +1 more source

Apoptosis of neuronal cells in the brains of postembryonic silkworms Bombyx mori (Lepidoptera: Bombycidae)

European Journal of Entomology, 2009
The pattern and signal transduction of neuronal apoptosis in the brain of the silk moth, Bombyx mori, during postembryonic life, were characterized. Peak numbers of apoptotic neurons were detected in 4 day old 4th instar larvae, 9 day old 5th instar ...
Mi Young KIM, Kang Kim MIN, Chang Ok CHOI, Hwa Young SONG, Chang Lee SEOK, Bong Woo KIM, Pil Don KANG, Soung Hoo JEON, Byung Pil CHO, Yeon Jae BAE, Young-Gyo KO, Bong Lee HEE   +11 more
doaj   +1 more source

Involvement of Reactive Oxygen Species in the Hepatorenal Toxicity of Actinomycin V In Vitro and In Vivo

Marine Drugs, 2020
The high toxicity of actinomycin D (Act D) severely limits its use as a first-line chemotherapeutic agent in the clinic. Actinomycin V (Act V), an analog of Act D, exhibited strong anticancer activity in our previous studies.
Fu-juan Jia, Zhuo Han, Jia-hui Ma, Shi-qing Jiang, Xing-ming Zhao, Hang Ruan, Wei-dong Xie, Xia Li   +7 more
doaj   +1 more source

Biocontrol of strawberry gray mold caused by Botrytis cinerea with the termite associated Streptomyces sp. sdu1201 and actinomycin D

Frontiers in Microbiology, 2022
Strawberry gray mold caused by Botrytis cinerea is one of the most severe diseases in pre- and post-harvest periods. Although fungicides have been an effective way to control this disease, they can cause serious “3R” problems (Resistance, Resurgence and ...
Daojing Yong, Daojing Yong, Yue Li, Kai Gong, Yingying Yu, Shuai Zhao, Qiong Duan, Cailing Ren, Aiying Li, Jun Fu, Jinfeng Ni, Youming Zhang, Youming Zhang, Ruijuan Li   +13 more
doaj   +1 more source

Anti-Oxidative and Anti-Apoptotic Effects of Apigenin on Number of Viable and Apoptotic Blastomeres, Zona Pellucida Thickness and Hatching Rate of Mouse Embryos [PDF]

International Journal of Fertility and Sterility, 2018
Background Apigenin is a plant-derived compound belonging to the flavonoids category and bears protective effects on different cells. The aim of this study was to evaluate the effect of apigenin on the number of viable and apoptotic blastomeres, the ...
Manouchehr Safari, Houman Parsaie, Hamid Reza Sameni, Mohammad Reza Aldaghi, Sam Zarbakhsh   +4 more
doaj   +1 more source

Comparing biweekly single-dose actinomycin D with multiday methotrexate therapy for low-risk gestational trophoblastic neoplasia (FIGO Score 0–4): study protocol for a prospective, multicentre, randomized trial

BMC Cancer, 2023
Background Single-agent chemotherapy using methotrexate or actinomycin D is the first-line treatment for patients with low-risk gestational trophoblastic neoplasia.
Fang Jiang, Ming-yi Mao, Yang Xiang, Xin Lu, Chong-li Guan, Lan-zhou Jiao, Xi-Run Wan, Feng-Zhi Feng, Tong Ren, Jun-Jun Yang, Jun Zhao   +10 more
doaj   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source