Results 111 to 120 of about 243,847 (379)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Claudins

European Journal of Histochemistry, 2012
I am pretty sure that I don’t have to spend a single word to talk about the role played by tight junctions in biological processes and in keeping alive the cellular bases of life !
Carlo Alberto Redi
doaj   +1 more source

SUMOylation of nuclear actin [PDF]

, 2009
Actin, a major component of the cytoplasm, is also abundant in the nucleus. Nuclear actin is involved in a variety of nuclear processes including transcription, chromatin remodeling, and intranuclear transport.
Alessandro Arduini, Aslan, Ball, Camacho, Camacho, Carlos J. Camacho, Chik, Chuang, Comeau, Comeau, Dantan-Gonzalez, Dignam, dos Remedios, Dundr, Field, Frances V. Fuller-Pace, Hay, Hofmann, Hofmann, Jacobs, James L. Lessard, Jockusch, Johnson, Kalderon, Karakozova, Kozakov, Kudo, Kudryashova, Lin, Lorenz, Louvet, Mandell, Matic, Matsuzaki, McDonald, Panse, Pendleton, Pestic-Dragovich, Posern, Primal de Lanerolle, Reverter, Rodriguez, Rosas-Acosta, Samantha M. Nicol, Schoenenberger, Schoenenberger, Stuven, Thom, Vertegaal, Wada, Wang, Westphal, Wilma A. Hofmann   +52 more
core   +5 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Epithelial Protein Lost in Neoplasm α (Eplin-α) is transcriptionally regulated by G-actin and MAL/MRTF coactivators

Molecular Cancer, 2010
Epithelial Protein Lost in Neoplasm α is a novel cytoskeleton-associated tumor suppressor whose expression inversely correlates with cell growth, motility, invasion and cancer mortality.
Hoffmann Reinhard, Descot Arnaud, Shaposhnikov Dmitry, Leitner Laura, Posern Guido   +4 more
doaj   +1 more source

Automatic human action recognition from video using Hidden Markov model [PDF]

, 2015
Posture classification is a key process for evaluating the behaviors of human being. Computer vision techniques can play a vital role in automating the overall process, however, occlusions, cluttered environment and illumination changes can make the ...
Afsar, Palwasha, Cortez, Paulo, Santos, Henrique   +2 more
core   +1 more source

An antiactin antibody that distinguishes between cytoplasmic and skeletal muscle actins

Journal of Cell Biology, 1980
We elicited antibodies in rabbits to actin purified from body wall muscle of the marine mollusc, Aplysia californica. We found that this antiactin has an unusual specificity: in addition to reacting with the immunogen, it recognizes cytoplasmic ...
B. Lubit, J. H. Schwartz
semanticscholar   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

The actin multigene family of Paramecium tetraurelia

BMC Genomics, 2007
Background A Paramecium tetraurelia pilot genome project, the subsequent sequencing of a Megabase chromosome as well as the Paramecium genome project aimed at gaining insight into the genome of Paramecium.
Wagner Erika, Reiner Christoph, Mansfeld Jörg, Sehring Ivonne M, Plattner Helmut, Kissmehl Roland   +5 more
doaj   +1 more source