Results 121 to 130 of about 75,213 (335)
A novel microfluidic flow-cytometry for counting numbers of single-cell β-actins
Nanotechnology and Precision Engineering, 2020 As a house keeping protein with stable expressions, β-actin is used as a loading control in normalization of western blotting. However, the actual numbers of β-actins at the single-cell level remain elusive.
Lixing Liu +6 more
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Atomic view into Plasmodium actin polymerization, ATP hydrolysis, and fragmentation.
PLoS Biology, 2019 Plasmodium actins form very short filaments and have a noncanonical link between ATP hydrolysis and polymerization. Long filaments are detrimental to the parasites, but the structural factors constraining Plasmodium microfilament lengths have remained ...
Esa-Pekka Kumpula +4 more
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Multiple essential functions of Plasmodium falciparum actin-1 during malaria blood-stage development
BMC Biology, 2017 Background The phylum Apicomplexa includes intracellular parasites causing immense global disease burden, the deadliest of them being the human malaria parasite Plasmodium falciparum, which invades and replicates within erythrocytes.
Sujaan Das +4 more
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Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
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Cell Reports, 2019 Summary: The unicellular green alga Chlamydomonas reinhardtii is a biflagellated cell with two actin genes: one encoding a conventional actin (IDA5) and the other encoding a divergent novel actin-like protein (NAP1).
Brittany Jack +4 more
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Communications ChemistryActin filament assembly and the regulation of its mechanical properties are fundamental processes essential for eukaryotic cell function. Residue E167 in vertebrate actins forms an inter-subunit salt bridge with residue K61 of the adjacent subunit ...
Xiao-Ping Xu +8 more
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Molecular Oncology, EarlyView.Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo +11 more
wiley +1 more source
Frontiers in Microbiology, 2016 Histones are small polycationic proteins located in the cell nucleus. Together, DNA and histones are integral constituents of the nucleosomes. Upon apoptosis, necrosis and infection - induced cell death, histones are released from the cell.
Asaf Sol +4 more
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Action of Cortisone on the Polymerization of Actin [PDF]
, 1953 J. B. COWLE, R. H. Thorp
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