Results 81 to 90 of about 240,879 (374)
Proceedings of the National Academy of Sciences of the United States of America, 1978 Muscle and cytoplasmic actins from several species have been compared by extensive fingerprint analysis and by partial amino acid sequence determination with the known amino acid sequence of rabbit muscle actin.
J. Vandekerckhove, K. Weber
semanticscholar +1 more source
FEBS Letters, EarlyView.Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt +4 more
wiley +1 more source
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source
Actin dynamics: Assembly and disassembly of actin networks [PDF]
Current Biology, 2000 Assembly of branched actin filament networks at the leading edge of migrating cells requires stimulation of the Arp2/3 complex by WASp proteins, in concert with the WASp activators Cdc42, PIP(2) and profilin. Network disassembly and debranching appears to be linked to actin-bound ATP hydrolysis as filaments age.
Martin A. Wear +2 more
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Conservation of conformational dynamics across prokaryotic actins.
PLoS Computational Biology, 2019 The actin family of cytoskeletal proteins is essential to the physiology of virtually all archaea, bacteria, and eukaryotes. While X-ray crystallography and electron microscopy have revealed structural homologies among actin-family proteins, these ...
Natalie Ng +3 more
doaj +1 more source
The origins of phagocytosis and eukaryogenesis
Biology Direct, 2009 Background Phagocytosis, that is, engulfment of large particles by eukaryotic cells, is found in diverse organisms and is often thought to be central to the very origin of the eukaryotic cell, in particular, for the acquisition of bacterial endosymbionts
Wolf Yuri I +3 more
doaj +1 more source
HIV Infection of T Cells: Actin-in and Actin-out [PDF]
Science Signaling, 2009 The coordinated activities of various actin-binding proteins facilitate entry of HIV into T cells.
Liu, Y., Belkina, N. V., Shaw, S.
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Septin filament organization in Saccharomyces cerevisiae. [PDF]
, 2012 Septins are a family of GTP-binding, membrane-interacting cytoskeletal proteins, highly conserved and essential in all eukaryotes (with the exception of plants). Septins play important roles in a number of cellular events that involve membrane remodeling
Bertin, Aurélie, NOGALES, Eva
core +1 more source
Purification tags markedly affect self‐aggregation of CPEB3
FEBS Letters, EarlyView.Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito +6 more
wiley +1 more source
Biophysical Journal, 2014 The protein actin exists as both a monomer (G-actin) and polymer (F-actin). There have been more than 80 different crystal structures of G-actin and related homologs over the years, and at least 4 different structures/models for F-actin have been proposed using a combination of techniques.
David Sept +2 more
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