Results 81 to 90 of about 31,296 (289)

シロイヌナズナアクチンアイソフォームの分子細胞生物学的研究 [PDF]

open access: yes, 2018
この博士論文は内容の要約のみの公開(または一部非公開)になっています筑波大学 (University of Tsukuba ...
KIJIMA Saku, 貴嶋 紗久
core   +1 more source

Relaxed and active thin filament structures; a new structural basis for the regulatory mechanism [PDF]

open access: yes, 2017
The structures of muscle thin filaments reconstituted using skeletal actin and cardiac troponin and tropomyosin have been determined with and without bound Ca2+ using electron microscopy and reference-free single particle analysis.
Morris, Edward   +2 more
core   +2 more sources

Actin droplet machine [PDF]

open access: yesRoyal Society Open Science, 2019
The actin droplet machine is a computer model of a three-dimensional network of actin bundles developed in a droplet of a physiological solution, which implements mappings of sets of binary strings. The actin bundle network is conductive to travelling excitations, i.e. impulses.
Andrew Adamatzky   +2 more
openaire   +5 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Dynamic Mechanisms of Cell Rigidity Sensing: Insights from a Computational Model of Actomyosin Networks [PDF]

open access: yes, 2012
Cells modulate themselves in response to the surrounding environment like substrate elasticity, exhibiting structural reorganization driven by the contractility of cytoskeleton. The cytoskeleton is the scaffolding structure of eukaryotic cells, playing a
A Engler   +47 more
core   +4 more sources

Actin, actin-binding proteins, and actin-related proteins in the nucleus [PDF]

open access: yesHistochemistry and Cell Biology, 2016
Extensive research in the past decade has significantly broadened our view about the role actin plays in the life of the cell and added novel aspects to actin research. One of these new aspects is the discovery of the existence of nuclear actin which became evident only recently.
Kristó, Ildikó   +4 more
openaire   +3 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Dipotassium 4,4′-(hexane-3,4-diyl)bis(benzenesulfonate) dihydrate

open access: yesActa Crystallographica Section E, 2008
The anion of the title compound, also called sygethin dihydrate, 2K+·C18H20O6S22−·2H2O, has crystallographic inversion symmetry. The K+ cation is surrounded by eight O atoms in a distorted cubic coordination geometry, forming extended K ...
Liana Orola   +3 more
doaj   +1 more source

Geometric pumping induced by shear flow in dilute liquid crystalline polymer solutions [PDF]

open access: yes, 2014
We investigate nonlinear rheology of dilute liquid crystalline polymer solutions under time dependent two-directional shear flow. We analyze the Smoluchowski equation, which describes the dynamics of the orientation of a liquid crystalline polymer, by ...
de Gennes P. G.   +4 more
core   +2 more sources

Actin Microridges [PDF]

open access: yesThe Anatomical Record, 2018
ABSTRACTMicroridges are highly distinctive “fingerprint”‐patterned structures situated on the outer surface of superficial layer cells of the epithelium. An F‐actin‐based cytoskeleton is the underlying core structural component of microridges. The basis for much of what is known about microridges has been provided by in vivo and in vitro fish ...
openaire   +2 more sources

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