Results 191 to 200 of about 1,854,011 (302)
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Discovering Cardiac Action Potential Model Equations Using Sparse Identification of Nonlinear Dynamics. [PDF]
Welch CS, Cherry EM.
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Impact of Evoked Compound Action Potential (ECAP)-Controlled Closed-Loop Spinal Cord Stimulation in Refractory Lumbar Radiculopathy: A Case Report. [PDF]
Soin A +4 more
europepmc +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Adaptations of the axon initial segment in fast-spiking interneurons of the human neocortex support low action potential thresholds. [PDF]
Bakos E +13 more
europepmc +1 more source

