Measuring Direct Oral Anticoagulant (DOAC) Levels: Applications, Limitations, and Future Directions
ABSTRACT Introduction There are important challenges with the measurement and interpretation of direct oral anticoagulant (DOAC) anticoagulant effect including a lack of therapeutic ranges, inaccuracy of routinely available coagulation assays, lack of established thresholds for clinically significant effect, and uncertainty about how to apply the ...
Siraj Mithoowani+2 more
wiley +1 more source
Prolonged Activated Partial Thromboplastin Time in Patients with Antiphospholipid Antibody Syndrome
James R. Dyer, Tilak Raj
openalex +2 more sources
From Activated Partial Thromboplastin Time to Antifactor Xa and Back Again. [PDF]
May JE+4 more
europepmc +1 more source
Classification of Platelet‐Activating Anti‐Platelet Factor 4 Disorders
ABSTRACT Introduction The prototypic anti‐platelet factor 4 (PF4) disorder—heparin‐induced thrombocytopenia and thrombosis (HITT)—features immunoglobulin G (IgG) class antibodies that activate platelets, monocytes, and neutrophils in a mainly heparin‐dependent fashion via Fcγ receptor‐dependent cellular activation.
Theodore E. Warkentin
wiley +1 more source
Changes in Some Haemostatic Parameters Among Patients with Chronic Kidney Disease in Kano Metropolis
It has long been accepted that Chronic Kidney Disease (CKD) causes alterations in haemostatic parameters. These changes have not been reported in our community.
Usman, M. D., *Garba, N., Danladi, S.B., Isah, S.Y., Audu, A., Dakata A.M., and Jelani, I.
doaj
Combined deficiency of factor V and factor VIII in a pediatric patient: a case report
Background Combined deficiency of factors V and VIII is a rare autosomal recessive disorder associated with an increased risk of bleeding. We present an unusual case of a 7-year-old Moroccan child with no history of consanguinity who was hospitalized ...
Yasmine Bendarkawi+4 more
doaj +1 more source
Predictive value of immunoglobulin G, activated partial thromboplastin time, platelet, and indirect bilirubin for delayed viral clearance in patients infected with the Omicron variant. [PDF]
Zhang L+10 more
europepmc +1 more source
Age-associated developmental changes in the activated partial thromboplastin time (APTT) and causes of prolonged APTT values in healthy Chinese children [PDF]
Jianxin Li+7 more
openalex +1 more source