Results 1 to 10 of about 7,192,504 (245)

Activated: Decentering activism in and with academia [PDF]

open access: yesCompanion Publication of the 2021 Conference on Computer Supported Cooperative Work and Social Computing, 2021
Who is an activist? With the advent of activism-related scholarship in HCI and CSCW, the current challenge involves thinking about what activism is, who an activist is, and the opportunities and limitations of activism. Recently, researchers in academia and industry, such as Timnit Gebru, demonstrate a commitment to stay activated for the structural ...
Lee, Minha   +4 more
openaire   +2 more sources

Buffy Coat Processing Impacts on Monocytes’ Capacity to Present Lipid Antigens

open access: yesBiomedicines, 2023
Buffy Coats, generated from a blood donor’s whole blood bag unit, are commonly used in biomedical research as a source of leukocytes due to the high number of cells that can be recovered from each Buffy Coat.
Inês Mondragão-Rodrigues   +1 more
doaj   +1 more source

To Activate or Not to Activate [PDF]

open access: yesCirculation Research, 2013
In a recent study, Watanabe et al identify a novel enhancer in the fgf10 locus that is necessary and sufficient for expression in anterior second heart field. Their results suggest a competitive mechanism in which Isl1 and Nkx2-5 bind the enhancer to activate or repress this enhancer, respectively.
Cornelis J, Boogerd, Sylvia M, Evans
openaire   +2 more sources

Detection of Glycosylated Markers From Cancer Stem Cells With ColoSTEM Dx Kit for Earlier Prediction of Colon Cancer Aggressiveness

open access: yesFrontiers in Oncology, 2022
Nowadays, colon cancer prognosis still difficult to predict, especially in the early stages. Recurrences remain elevated, even in the early stages after curative surgery.
Sabrina Blondy   +16 more
doaj   +1 more source

Dance as an agency of change in an age of totalitarianism

open access: yesApproaching Religion, 2022
This article identifies two different paths where the amnesia described by Hannah- Arendt and the fragmentation identified by Willie James Jennings of our historical past has distorted how people today view dan-cing.
Laura Hellsten
doaj   +1 more source

Development of a novel light-up probe for detection of G-quadruplexes in stress granules

open access: yesScientific Reports, 2022
G-quadruplexes (G4s) regulate various biological processes in cells. However, cellular imaging of dynamically forming G4s in biomolecular condensates using small molecules has been poorly investigated. Herein, we present a fluorescent light-up probe with
Keisuke Iida   +4 more
doaj   +1 more source

A Label-Free Cell Sorting Approach to Highlight the Impact of Intratumoral Cellular Heterogeneity and Cancer Stem Cells on Response to Therapies

open access: yesCells, 2022
Cancer stem cells play a crucial role in tumor initiation, metastasis, and resistance to treatment. Cellular heterogeneity and plasticity complicate the isolation of cancer stem cells.
Céline Hervieu   +8 more
doaj   +1 more source

The M1 and M2 paradigm of macrophage activation: time for reassessment

open access: yesF1000Prime Reports, 2014
Macrophages are endowed with a variety of receptors for lineage-determining growth factors, T helper (Th) cell cytokines, and B cell, host, and microbial products.
F. Martínez, S. Gordon
semanticscholar   +1 more source

Inherited immunodeficiencies associated with proximal and distal defects in T cell receptor signaling and co-signaling

open access: yesBiomedical Journal, 2022
T lymphocytes are central cells of adaptive immunity. Activation of T lymphocytes by the antigen receptor of T cells (TCR) and co-stimulatory molecules involve specific signaling components and cascades.
Sylvain Latour
doaj   +1 more source

The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation

open access: yesInternational Journal of Molecular Sciences, 2019
The NLRP3 inflammasome is a critical component of the innate immune system that mediates caspase-1 activation and the secretion of proinflammatory cytokines IL-1β/IL-18 in response to microbial infection and cellular damage.
N. Kelley   +3 more
semanticscholar   +1 more source

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