Results 161 to 170 of about 11,119 (186)

Activation-Induced Cytidine Deaminase Expression in Human B Cell Precursors Is Essential for Central B Cell Tolerance. [PDF]

Immunity, 2015
Cantaert T, Schickel JN, Bannock JM, Ng YS, Massad C, Oe T, Wu R, Lavoie A, Walter JE, Notarangelo LD, Al-Herz W, Kilic SS, Ochs HD, Nonoyama S, Durandy A, Meffre E.   +15 more
europepmc   +1 more source

Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic mice

, 2007
Ai Kotani, Naoki Kakazu, Tatsuaki Tsuruyama, Il‐mi Okazaki, Masamichi Muramatsu, Kazuo Kinoshita, Hitoshi Nagaoka, Daisuke Yabe, Tasuku Honjo   +8 more
openalex   +1 more source

Activation-induced cytidine deaminase prevents pro-B cell acute lymphoblastic leukemia by functioning as a negative regulator in Rag1 deficient pro-B cells. [PDF]

Oncotarget, 2017
Auer F, Ingenhag D, Pinkert S, Kracker S, Hacein-Bey-Abina S, Cavazzana M, Gombert M, Martin-Lorenzo A, Lin MH, Vicente-Dueñas C, Sánchez-García I, Borkhardt A, Hauer J.   +12 more
europepmc   +1 more source

Critical role of activation induced cytidine deaminase in experimental autoimmune encephalomyelitis. [PDF]

Autoimmunity, 2013
Sun Y, Peng I, Senger K, Hamidzadeh K, Reichelt M, Baca M, Yeh R, Lorenzo MN, Sebrell A, Dela Cruz C, Tam L, Corpuz R, Wu J, Sai T, Roose-Girma M, Warming S, Balazs M, Gonzalez LC, Caplazi P, Martin F, Devoss J, Zarrin AA.   +21 more
europepmc   +1 more source

RAD51 homolog (RAD51); activation-induced cytidine deaminase (AICDA; AID) [PDF]

Science-Business eXchange, 2013
openaire   +1 more source

Deaminase Modulation Driving a New Era in Drug Development. [PDF]

Int J Mol Sci
Lindley RA.
europepmc   +1 more source

Synthetic Pentatricopeptide Repeat Proteins: Building a Toolkit for Precise RNA Control. [PDF]

Int J Mol Sci
Lombana JM, Hanson MR, Bentolila S.
europepmc   +1 more source

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Activation-induced cytidine deaminase and active cytidine demethylation

Trends in Biochemical Sciences, 2015
The regulation of demethylation in vertebrates has begun to be elucidated in the past decade. However, a possible involvement of activation-induced cytidine deaminase (AID) in this process remains uncertain. We survey the data supporting or casting doubt on such a role, and propose that there is no strong evidence for an involvement of AID in genome ...
Almudena R, Ramiro, Vasco M, Barreto
openaire   +2 more sources

Molecular characterization of Pleurodeles waltl activation-induced cytidine deaminase☆

Molecular Immunology, 2010
Activation-induced cytidine deaminase (AID) is involved in immunoglobulin affinity maturation, gene conversion and class switch recombination. This protein is therefore a major actor in the creation of the antibody repertoire. We have isolated, for the first time, the AID mRNA from a urodele amphibian, Pleurodeles waltl.
Matthieu, Bascove, Jean-Pol, Frippiat
openaire   +2 more sources

The role of activation-induced cytidine deaminase in lymphomagenesis

Current Opinion in Hematology, 2012
Activation-induced cytidine deaminase (AID) is expressed in germinal center B cells and initiates the events that lead to somatic hypermutation and class switch recombination of immunoglobulin genes. In addition to this fundamental role in immune diversification, aberrant targeting of AID activity contributes to point mutations and translocations of ...
Xiwen, Gu, Velizar, Shivarov, Matthew P, Strout   +2 more
openaire   +2 more sources